7Z3R
 
 | | Crystal structure of the mouse leptin:LepR-IgCRH2 complex to 2.95 A resolution. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor | | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N, Tsirigotaki, A. | | 登録日 | 2022-03-02 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.951 Å) | | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
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7Z3P
 | | Crystal structure of the mouse leptin:LepR-CRH2 encounter complex to 1.95 A resolution. | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Leptin, ... | | 著者 | Tsirigotaki, A, Verschueren, K, Savvides, S.N, Verstraete, K. | | 登録日 | 2022-03-02 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.943 Å) | | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
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7Z3Q
 | | Crystal structure of the human leptin:LepR-CRH2 encounter complex to 3.6 A resolution. | | 分子名称: | Leptin, Leptin receptor | | 著者 | Verstraete, K, Verschueren, K, Alexandra, T, Savvides, S.N. | | 登録日 | 2022-03-02 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.617 Å) | | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
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8P8T
 | | Ex vivo Ym2 crystal structure | | 分子名称: | Chitinase-like protein 4, GLYCEROL | | 著者 | Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, H, Savvides, S.N, Lambrecht, B.N. | | 登録日 | 2023-06-02 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
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8P8Q
 | | Recombinant Ym1 crystal structure | | 分子名称: | ACETATE ION, Chitinase-like protein 3, GLYCEROL | | 著者 | Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Aegerter, H, Smole, U, Savvides, S.N, Lambrecht, B.N. | | 登録日 | 2023-06-02 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | | 主引用文献 | Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
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8P8S
 | | Recombinant Ym2 crystal structure | | 分子名称: | 1,2-ETHANEDIOL, Chitinase-like protein 4 | | 著者 | Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, A, Savvides, S.N, Lambrecht, B.N. | | 登録日 | 2023-06-02 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
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8P8R
 | | Ex vivo Ym1 crystal structure | | 分子名称: | 1,2-ETHANEDIOL, Chitinase-like protein 3 | | 著者 | Verschueren, K.H.G, Verstraete, K, Heyndrickx, I, Smole, U, Aegerter, H, Savvides, S.N, Lambrecht, B.N. | | 登録日 | 2023-06-02 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Ym1 protein crystals promote type 2 immunity.
Elife, 12, 2024
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6QCL
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6QFB
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6GLX
 | | Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 4E8 | | 分子名称: | Fab 4E8 - Heavy chain, Fab 4E8 - Light chain, Galectin-10 | | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N. | | 登録日 | 2018-05-23 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.396 Å) | | 主引用文献 | Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
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6GKU
 | | Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 6F5 | | 分子名称: | CALCIUM ION, Fab 6F5 - Heavy Chain, Fab 6F5 - Light chain, ... | | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N. | | 登録日 | 2018-05-21 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
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6GLW
 | | Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 1D11 | | 分子名称: | ACETATE ION, Fab 1D11 - Heavy chain, Fab 1D11 - Light chain, ... | | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N. | | 登録日 | 2018-05-23 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
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6GKT
 | | X-ray structure of a non-autocrystallizing galectin-10 variant, Gal10-Tyr69Glu | | 分子名称: | Galectin-10, HEXAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... | | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N. | | 登録日 | 2018-05-21 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Protein crystallization promotes type 2 immunity and is reversible by antibody treatment.
Science, 364, 2019
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6GKS
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6GKQ
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6HXO
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6HXI
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6HXH
 | | Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase,Human ATP citrate lyase, CITRATE ANION, ... | | 著者 | Verstraete, K, Verschueren, K. | | 登録日 | 2018-10-17 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
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6HXL
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6HXP
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6HXN
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6HXQ
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6HXM
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6HXK
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6HXJ
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