2FTK
 
 | | berylloflouride Spo0F complex with Spo0B | | 分子名称: | MAGNESIUM ION, Sporulation initiation phosphotransferase B, Sporulation initiation phosphotransferase F | | 著者 | Varughese, K.I. | | 登録日 | 2006-01-24 | | 公開日 | 2006-07-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | The Crystal Structure of Beryllofluoride Spo0F in Complex with the Phosphotransferase Spo0B Represents a Phosphotransfer Pretransition State.
J.Bacteriol., 188, 2006
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1DHR
 | | CRYSTAL STRUCTURE OF RAT LIVER DIHYDROPTERIDINE REDUCTASE | | 分子名称: | DIHYDROPTERIDINE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Varughese, K.I, Skinner, M.M, Whiteley, J.M, Matthews, D.A, Xuong, N.H. | | 登録日 | 1992-03-30 | | 公開日 | 1993-07-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of rat liver dihydropteridine reductase.
Proc.Natl.Acad.Sci.USA, 89, 1992
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1AEC
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1QYY
 | | Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 2.8 Angstrom Resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PLATINUM (II) ION, Platelet glycoprotein Ib alpha chain, ... | | 著者 | Varughese, K.I, Ruggeri, Z.M, Celikel, R. | | 登録日 | 2003-09-12 | | 公開日 | 2004-03-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Platinum-induced space-group transformation in crystals of the platelet glycoprotein Ib alpha N-terminal domain.
Acta Crystallogr.,Sect.D, 60, 2004
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1IXM
 | | CRYSTAL STRUCTURE OF SPOOB FROM BACILLUS SUBTILIS | | 分子名称: | PROTEIN (SPORULATION RESPONSE REGULATORY PROTEIN) | | 著者 | Varughese, K.I. | | 登録日 | 1998-11-06 | | 公開日 | 1998-11-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Formation of a novel four-helix bundle and molecular recognition sites by dimerization of a response regulator phosphotransferase.
Mol.Cell, 2, 1998
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3PMH
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1FNS
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1DIR
 | | CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER | | 分子名称: | DIHYDROPTERIDINE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Varughese, K.I, Su, Y, Skinner, M.M, Matthews, D.A, Whitely, J.M, Xuong, N.H. | | 登録日 | 1994-04-18 | | 公開日 | 1994-07-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of a monoclinic form of dihydropteridine reductase from rat liver.
Acta Crystallogr.,Sect.D, 50, 1994
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1OOK
 | | Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Human Alpha Thrombin, ... | | 著者 | Varughese, K.I, Celikel, R, Ruggeri, Z.M. | | 登録日 | 2003-03-03 | | 公開日 | 2003-07-22 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Modulation of alpha-thrombin function by distinct interactions with platelet
glycoprotein Ibalpha
Science, 301, 2003
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1P9A
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1HDR
 | | THE CRYSTALLOGRAPHIC STRUCTURE OF A HUMAN DIHYDROPTERIDINE REDUCTASE NADH BINARY COMPLEX EXPRESSED IN ESCHERICHIA COLI BY A CDNA CONSTRUCTED FROM ITS RAT HOMOLOGUE | | 分子名称: | DIHYDROPTERIDINE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Varughese, K.I, Su, Y, Xuong, N.H, Whiteley, J.M. | | 登録日 | 1993-08-18 | | 公開日 | 1994-08-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystallographic structure of a human dihydropteridine reductase NADH binary complex expressed in Escherichia coli by a cDNA constructed from its rat homologue.
J.Biol.Chem., 268, 1993
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2ZKZ
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4GQP
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1SRR
 | | CRYSTAL STRUCTURE OF A PHOSPHATASE RESISTANT MUTANT OF SPORULATION RESPONSE REGULATOR SPO0F FROM BACILLUS SUBTILIS | | 分子名称: | CALCIUM ION, SPORULATION RESPONSE REGULATORY PROTEIN | | 著者 | Madhusudan, Whiteley, J.M, Hoch, J.A, Zapf, J, Xuong, N.H, Varughese, K.I. | | 登録日 | 1996-04-10 | | 公開日 | 1997-04-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of a phosphatase-resistant mutant of sporulation response regulator Spo0F from Bacillus subtilis.
Structure, 4, 1996
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1OAK
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3GM0
 | | Anti-methamphetamine single chain Fv in complex with MDMA | | 分子名称: | (2S)-1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine, anti-methamphetamine single chain Fv | | 著者 | Celikel, R, Peterson, E.C, Owens, M, Varughese, K.I. | | 登録日 | 2009-03-12 | | 公開日 | 2009-10-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of a therapeutic single chain antibody in complex with two drugs of abuse-Methamphetamine and 3,4-methylenedioxymethamphetamine.
Protein Sci., 18, 2009
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3SL2
 | | ATP Forms a Stable Complex with the Essential Histidine Kinase WalK (YycG) Domain | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Sensor histidine kinase yycG | | 著者 | Celikel, R, Veldore, V.H, Mathews, I, Devine, K, Varughese, K.I. | | 登録日 | 2011-06-23 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | ATP forms a stable complex with the essential histidine kinase WalK (YycG) domain.
Acta Crystallogr.,Sect.D, 68, 2012
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3GKZ
 | | Crystal structures of a therapeutic single chain antibody in complex methamphetamine | | 分子名称: | (2S)-N-methyl-1-phenylpropan-2-amine, anti-methamphetamine single chain Fv | | 著者 | Celikel, R, Peterson, E.C, Owens, M, Varughese, K.I. | | 登録日 | 2009-03-11 | | 公開日 | 2009-10-06 | | 最終更新日 | 2019-09-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of a therapeutic single chain antibody in complex with two drugs of abuse-Methamphetamine and 3,4-methylenedioxymethamphetamine.
Protein Sci., 18, 2009
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4QRA
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4QRB
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4QR7
 | | Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation | | 分子名称: | (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, GLCNAC(BETA1-4)-MURNAC(1,6-ANHYDRO)-L-ALA-GAMMA-D-GLU-MESO-A2PM-D-ALA, L,d-transpeptidase LdtB | | 著者 | Gokulan, K, Varughese, K.I. | | 登録日 | 2014-06-30 | | 公開日 | 2015-07-29 | | 最終更新日 | 2022-02-02 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation
To be Published
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4QTF
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7XMP
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2FGT
 | | Crystal Structure of YycH from Bacillus subtilis | | 分子名称: | Two-component system yycF/yycG regulatory protein yycH | | 著者 | Szurmant, H, Zhao, H, Mohan, M.A, James, H.A, Varughese, K.I. | | 登録日 | 2005-12-22 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The crystal structure of YycH involved in the regulation of the essential YycFG two-component system in Bacillus subtilis reveals a novel tertiary structure.
Protein Sci., 15, 2006
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1LQ1
 | | DNA Complexed Structure of the Key Transcription Factor Initiating Development in Sporulation Bacteria | | 分子名称: | 5'-D(*AP*CP*AP*AP*AP*AP*TP*TP*CP*GP*AP*CP*AP*CP*GP*A)-3', 5'-D(*TP*TP*CP*GP*TP*GP*TP*CP*GP*AP*AP*TP*TP*TP*TP*G)-3', Stage 0 sporulation protein A | | 著者 | Zhao, H, Msadek, T, Zapf, J, Madhusudan, Hoch, J.A, Varughese, K.I. | | 登録日 | 2002-05-08 | | 公開日 | 2002-08-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | DNA complexed structure of the key transcription factor initiating development in sporulating bacteria.
Structure, 10, 2002
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