4QRA

Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation

Summary for 4QRA

• Entry DOI: 10.2210/pdb4qra/pdb
• Related: 4QR7 4QRB
• Descriptor: L,d-transpeptidase LdtB, CALCIUM ION (3 entities in total)
• Functional Keywords: structural genomics, enzyme function initiative, center for structural genomics of infectious diseases, csgid, l-d-transpeptidase; d-d-transpeptidase; single anomalous diffraction; imipenem; meropenem;, hydrolase
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cell membrane ; Lipid-anchor : I6Y9J2
• Total number of polymer chains: 2
• Total formula weight: 75397.77

Authors

Gokulan, K.,Varughese, K.I. (deposition date: 2014-06-30, release date: 2015-12-23, Last modification date: 2024-02-28)

• Primary citation: Gokulan, K.,Khare, S.,Cerniglia, C.E.,Foley, S.L.,Varughese, K.I.; Structure and specificity of L-D-Transpeptidase from Mycobacterium tuberculosis and antibiotic resistance: Calcium binding promotes dimer formation; To be Published,

Experimental method

X-RAY DIFFRACTION (2.29 Å)