8BWS
 
 | | Structure of yeast RNA Polymerase III elongation complex at 3.3 A | | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | 著者 | Nguyen, P.Q, Fernandez-Tornero, C. | | 登録日 | 2022-12-07 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
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1HKQ
 | | PPS10 plasmid DNA replication initiator protein RepA. Replication inactive, dimeric N-terminal domain. | | 分子名称: | BENZOIC ACID, MERCURY (II) ION, PHOSPHATE ION, ... | | 著者 | Giraldo, R, Fernandez-Tornero, C, Evans, P.R, Diaz-Orejas, R, Romero, A. | | 登録日 | 2003-03-11 | | 公開日 | 2003-05-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | A Conformational Switch between Transcriptional Repression and Replication Initiation in Repa Dimerization Domain
Nat.Struct.Biol., 10, 2003
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1HKN
 | | A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate | | 分子名称: | 5-AMINO-NAPHTALENE-2-MONOSULFONATE, HEPARIN-BINDING GROWTH FACTOR 1 | | 著者 | Fernandez-Tornero, C, Lozano, R.M, Gimenez-Gallego, G, Romero, A. | | 登録日 | 2003-03-10 | | 公開日 | 2004-03-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate
J.Biol.Chem., 278, 2003
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8RTH
 | | Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase | | 分子名称: | 3-methylcrotonyl-CoA carboxylase, putative, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ... | | 著者 | Ruiz, F.M, Plaza-Pegueroles, A, Fernandez-Tornero, C. | | 登録日 | 2024-01-26 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.37 Å) | | 主引用文献 | The cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase provides mechanistic and dynamic insights into its enzymatic function.
Structure, 32, 2024
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3NSU
 | | A Systematic Screen for Protein-Lipid Interactions in Saccharomyces cerevisiae | | 分子名称: | Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1, SULFATE ION | | 著者 | Gallego, O, Fernandez-Tornero, C, Aguilar-Gurrieri, C, Muller, C, Gavin, A.C. | | 登録日 | 2010-07-02 | | 公開日 | 2010-12-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae.
Mol. Syst. Biol., 6, 2010
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2BML
 | | Ofloxacin-like antibiotics inhibit pneumococcal cell wall degrading virulence factors | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AUTOLYSIN, DEXTROFLOXACINE, ... | | 著者 | Fernandez-Tornero, C, Gimenez-Gallego, G, Romero, A, Garcia, E, Pascual-Teresa, B.D, Lopez, R. | | 登録日 | 2005-03-15 | | 公開日 | 2005-03-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Ofloxacin-Like Antibiotics Inhibit Pneumococcal Cell Wall-Degrading Virulence Factors
J.Biol.Chem., 280, 2005
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2YN2
 | | Huf protein - paralogue of the tau55 histidine phosphatase domain | | 分子名称: | FORMIC ACID, UNCHARACTERIZED PROTEIN YNL108C | | 著者 | Taylor, N.M.I, Glatt, S, Hennrich, M, von Scheven, G, Grotsch, H, Fernandez-Tornero, C, Rybin, V, Gavin, A.C, Kolb, P, Muller, C.W. | | 登録日 | 2012-10-11 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor Tfiiic.
J.Biol.Chem., 288, 2013
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2YN0
 | | tau55 histidine phosphatase domain | | 分子名称: | PHOSPHATE ION, TRANSCRIPTION FACTOR TAU 55 KDA SUBUNIT | | 著者 | Taylor, N.M.I, Glatt, S, Hennrich, M, von Scheven, G, Grotsch, H, Fernandez-Tornero, C, Rybin, V, Gavin, A.C, Kolb, P, Muller, C.W. | | 登録日 | 2012-10-11 | | 公開日 | 2013-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor Iiic.
J.Biol.Chem., 288, 2013
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1GVM
 | | CHOLINE BINDING DOMAIN OF THE MAJOR AUTOLYSIN (C-LYTA) FROM STREPTOCOCCUS PNEUMONIAE | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AUTOLYSIN, CHOLINE ION, ... | | 著者 | Fernandez-Tornero, C, Lopez, R, Garcia, E, Gimenez-Gallego, G, Romero, A. | | 登録日 | 2002-02-15 | | 公開日 | 2002-08-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Two New Crystal Forms of the Choline-Binding Domain of the Major Pneumococcal Autolysin: Insights Into the Dynamics of the Active Dimeric
J.Mol.Biol., 321, 2002
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7Z0H
 | | Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40). | | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | 著者 | Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C. | | 登録日 | 2022-02-22 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
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7Z31
 | | Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore). | | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | 著者 | Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C. | | 登録日 | 2022-03-01 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
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7Z30
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7Z2Z
 | | Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A | | 分子名称: | (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | | 著者 | Nguyen, P.Q, Fernandez-Tornero, C. | | 登録日 | 2022-03-01 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
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2J04
 | | The tau60-tau91 subcomplex of yeast transcription factor IIIC | | 分子名称: | HYPOTHETICAL PROTEIN YPL007C, YDR362CP | | 著者 | Mylona, A, Fernandez-Tornero, C, Legrand, P, Muller, C.W. | | 登録日 | 2006-07-31 | | 公開日 | 2006-10-23 | | 最終更新日 | 2019-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of the Tau60/Deltatau91 Subcomplex of Yeast Transcription Factor Iiic: Insights Into Preinitiation Complex Assembly
Mol.Cell, 24, 2006
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6H68
 | | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) with fully-ordered A49 | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C. | | 登録日 | 2018-07-26 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis of RNA polymerase I stalling at UV light-induced DNA damage.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6H67
 | | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C. | | 登録日 | 2018-07-26 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of RNA polymerase I stalling at UV light-induced DNA damage.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5LMX
 | | Monomeric RNA polymerase I at 4.9 A resolution | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Torreira, E, Louro, J.A, Gil-Carton, D, Gallego, O, Calvo, O, Fernandez-Tornero, C. | | 登録日 | 2016-08-02 | | 公開日 | 2017-03-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | The dynamic assembly of distinct RNA polymerase I complexes modulates rDNA transcription.
Elife, 6, 2017
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6YD1
 | | SaFtsZ-DFMBA | | 分子名称: | 2,6-difluoro-3-methoxybenzamide, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | | 登録日 | 2020-03-20 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery.
J.Med.Chem., 64, 2021
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6YD6
 | | SaFtsZ-UCM152 (comp.20) | | 分子名称: | 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, 2,6-bis(fluoranyl)-3-[[3-(trifluoromethyl)phenyl]methoxy]benzamide, ... | | 著者 | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | | 登録日 | 2020-03-20 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery.
J.Med.Chem., 64, 2021
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6YD5
 | | SaFtsZ-UCM151 (comp. 18) | | 分子名称: | 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, 3-[(3-chlorophenyl)methoxy]-2,6-bis(fluoranyl)benzamide, ... | | 著者 | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | | 登録日 | 2020-03-20 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery.
J.Med.Chem., 64, 2021
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2BYM
 | | Histone fold heterodimer of the Chromatin Accessibility Complex | | 分子名称: | CADMIUM ION, CHRAC-14, CHRAC-16 | | 著者 | Fernandez-Tornero, C, Hartlepp, K.F, Grune, T, Eberharter, A, Becker, P.B, Muller, C.W. | | 登録日 | 2005-08-03 | | 公開日 | 2005-11-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The Histone Fold Subunits of Drosophila Chrac Facilitate Nucleosome Sliding Through Dynamic DNA Interactions.
Mol.Cell.Biol., 25, 2005
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2BYK
 | | Histone fold heterodimer of the Chromatin Accessibility Complex | | 分子名称: | CHRAC-14, CHRAC-16, SULFATE ION | | 著者 | Fernandez-Tornero, C, Hartlepp, K.F, Grune, T, Eberharter, A, Becker, P.B, Muller, C.W. | | 登録日 | 2005-08-03 | | 公開日 | 2005-11-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Histone Fold Subunits of Drosophila Chrac Facilitate Nucleosome Sliding Through Dynamic DNA Interactions.
Mol.Cell.Biol., 25, 2005
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1H8G
 | | C-terminal domain of the major autolysin (C-LytA) from Streptococcus pneumoniae | | 分子名称: | CHOLINE ION, MAJOR AUTOLYSIN | | 著者 | Fernandez-Tornero, C, Garcia, E, Lopez, R, Gimenez-Gallego, G, Romero, A. | | 登録日 | 2001-02-06 | | 公開日 | 2002-01-31 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A Novel Solenoid Fold in the Cell Wall Anchoring Domain of the Pneumococcal Virulence Factor Lyta
Nat.Struct.Biol., 8, 2001
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1HCX
 | | Choline binding domain of the major autolysin (C-LytA) from Streptococcus pneumoniae | | 分子名称: | 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride, CHOLINE ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, ... | | 著者 | Fernandez-Tornero, C, Lopez, R, Garcia, E, Gimenez-Gallego, G, Romero, A. | | 登録日 | 2001-05-10 | | 公開日 | 2001-11-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A Novel Solenoid Fold in the Cell Wall Anchoring Domain of the Pneumococcal Virulence Factor Lyta
Nat.Struct.Biol., 8, 2001
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1H8P
 | | Bull seminal plasma PDC-109 fibronectin type II module | | 分子名称: | PHOSPHOCHOLINE, SEMINAL PLASMA PROTEIN PDC-109 | | 著者 | Wah, D.A, Fernandez-Tornero, C, Calvete, J.J, Romero, A. | | 登録日 | 2001-02-14 | | 公開日 | 2002-04-12 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Sperm Coating Mechanism from the 1.8 A Crystal Structure of Pdc-109-Phosphorylcholine Complex
Structure, 10, 2002
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