6YD6

SaFtsZ-UCM152 (comp.20)

Summary for 6YD6

Entry DOI	10.2210/pdb6yd6/pdb
Descriptor	Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, 2,6-bis(fluoranyl)-3-[[3-(trifluoromethyl)phenyl]methoxy]benzamide, ... (7 entities in total)
Functional Keywords	cell division protein, cell cycle
Biological source	Staphylococcus aureus
Total number of polymer chains	1
Total formula weight	32712.67
Authors	Fernandez-Tornero, C.,Ruiz, F.M.,Andreu, J.M. (deposition date: 2020-03-20, release date: 2021-07-28, Last modification date: 2024-01-24)
Primary citation	Huecas, S.,Araujo-Bazan, L.,Ruiz, F.M.,Ruiz-Avila, L.B.,Martinez, R.F.,Escobar-Pena, A.,Artola, M.,Vazquez-Villa, H.,Martin-Fontecha, M.,Fernandez-Tornero, C.,Lopez-Rodriguez, M.L.,Andreu, J.M. Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery. J.Med.Chem., 64:5730-5745, 2021 Cited by PubMed: 33908781 DOI: 10.1021/acs.jmedchem.0c02207 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation