6EU4
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5NJG
| Structure of an ABC transporter: part of the structure that could be built de novo | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... | 著者 | Taylor, N.M.I, Manolaridis, I, Jackson, S.M, Kowal, J, Stahlberg, H, Locher, K.P. | 登録日 | 2017-03-28 | 公開日 | 2017-06-07 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Structure of the human multidrug transporter ABCG2. Nature, 546, 2017
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5NJ3
| Structure of an ABC transporter: complete structure | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... | 著者 | Taylor, N.M.I, Manolaridis, I, Jackson, S.M, Kowal, J, Stahlberg, H, Locher, K.P. | 登録日 | 2017-03-28 | 公開日 | 2017-06-07 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Structure of the human multidrug transporter ABCG2. Nature, 546, 2017
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2YN2
| Huf protein - paralogue of the tau55 histidine phosphatase domain | 分子名称: | FORMIC ACID, UNCHARACTERIZED PROTEIN YNL108C | 著者 | Taylor, N.M.I, Glatt, S, Hennrich, M, von Scheven, G, Grotsch, H, Fernandez-Tornero, C, Rybin, V, Gavin, A.C, Kolb, P, Muller, C.W. | 登録日 | 2012-10-11 | 公開日 | 2013-04-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor Tfiiic. J.Biol.Chem., 288, 2013
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2YN0
| tau55 histidine phosphatase domain | 分子名称: | PHOSPHATE ION, TRANSCRIPTION FACTOR TAU 55 KDA SUBUNIT | 著者 | Taylor, N.M.I, Glatt, S, Hennrich, M, von Scheven, G, Grotsch, H, Fernandez-Tornero, C, Rybin, V, Gavin, A.C, Kolb, P, Muller, C.W. | 登録日 | 2012-10-11 | 公開日 | 2013-04-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor Iiic. J.Biol.Chem., 288, 2013
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4BJJ
| Sfc1-Sfc7 dimerization module | 分子名称: | MERCURY (II) ION, TRANSCRIPTION FACTOR TAU SUBUNIT SFC1, TRANSCRIPTION FACTOR TAU SUBUNIT SFC7 | 著者 | Taylor, N.M.I, Baudin, F, von Scheven, G, Muller, C.W. | 登録日 | 2013-04-18 | 公開日 | 2013-07-31 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | RNA Polymerase III-Specific General Transcription Factor Iiic Contains a Heterodimer Resembling Tfiif RAP30/RAP74. Nucleic Acids Res., 41, 2013
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4BJI
| Sfc1-DBD | 分子名称: | TRANSCRIPTION FACTOR TAU SUBUNIT SFC1 | 著者 | Taylor, N.M.I, Baudin, F, von Scheven, G, Muller, C.W. | 登録日 | 2013-04-18 | 公開日 | 2013-07-31 | 最終更新日 | 2013-11-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | RNA Polymerase III-Specific General Transcription Factor Iiic Contains a Heterodimer Resembling Tfiif RAP30/RAP74. Nucleic Acids Res., 41, 2013
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5LYE
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7B75
| Cryo-EM Structure of Human Thyroglobulin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thyroglobulin, ... | 著者 | Adaixo, R, Righetto, R, Steiner, E.M, Taylor, N.M.I, Stahlberg, H. | 登録日 | 2020-12-09 | 公開日 | 2021-12-29 | 最終更新日 | 2022-01-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of native human thyroglobulin. Nat Commun, 13, 2022
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6FFC
| Structure of an inhibitor-bound ABC transporter | 分子名称: | ATP-binding cassette sub-family G member 2, ~{tert}-butyl 3-[(2~{S},5~{S},8~{S})-14-cyclopentyloxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate | 著者 | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. | 登録日 | 2018-01-06 | 公開日 | 2018-04-11 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | 主引用文献 | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat. Struct. Mol. Biol., 25, 2018
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6HZM
| Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium (alternative placement of Magnesium into the cryo-EM density) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 2, MAGNESIUM ION | 著者 | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | 登録日 | 2018-10-23 | 公開日 | 2018-11-14 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states. Nature, 563, 2018
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6HIJ
| Cryo-EM structure of the human ABCG2-MZ29-Fab complex with cholesterol and PE lipids docked | 分子名称: | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ATP-binding cassette sub-family G member 2, CHOLESTEROL, ... | 著者 | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Taylor, N.M.I, Bause, M, Bauer, S, Bartholomaeus, R, Stahlberg, H, Bernhardt, G, Koenig, B, Buschauer, A, Altmann, K.H, Locher, K.P. | 登録日 | 2018-08-30 | 公開日 | 2018-09-19 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | 主引用文献 | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2. Nat.Struct.Mol.Biol., 25, 2018
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6HBU
| Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 2, MAGNESIUM ION | 著者 | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | 登録日 | 2018-08-13 | 公開日 | 2018-11-07 | 最終更新日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states. Nature, 563, 2018
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6HCO
| Cryo-EM structure of the ABCG2 E211Q mutant bound to estrone 3-sulfate and 5D3-Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ... | 著者 | Manolaridis, I, Jackson, S.M, Taylor, N.M.I, Kowal, J, Stahlberg, H, Locher, K.P. | 登録日 | 2018-08-15 | 公開日 | 2018-11-07 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states. Nature, 563, 2018
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6YKP
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6YKM
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6YKR
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6RTB
| cryo-em structure of alpha-synuclein fibril polymorph 2B | 分子名称: | Alpha-synuclein | 著者 | Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. | 登録日 | 2019-05-22 | 公開日 | 2019-06-26 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy. Elife, 8, 2019
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6RT0
| cryo-em structure of alpha-synuclein fibril polymorph 2A | 分子名称: | Alpha-synuclein | 著者 | Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. | 登録日 | 2019-05-22 | 公開日 | 2019-06-26 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy. Elife, 8, 2019
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8BRI
| VaPomAB MSP1D1 nanodisc | 分子名称: | Chemotaxis protein PomA, Flagellar motor protein | 著者 | Hu, H, Taylor, N.M.I. | 登録日 | 2022-11-23 | 公開日 | 2023-06-14 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit. Nat Commun, 14, 2023
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8BRD
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8BWO
| Cryo-EM structure of nanodisc-reconstituted human MRP4 with E1202Q mutation (outward-facing occluded conformation) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, MAGNESIUM ION | 著者 | Raj, I, Bloch, M, Pape, T.H, Taylor, N.M.I. | 登録日 | 2022-12-07 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4. Structure, 31, 2023
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8BJF
| Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (inward-facing conformation) | 分子名称: | ATP-binding cassette sub-family C member 4, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE | 著者 | Raj, I, Bloch, M, Pape, T.H, Taylor, N.M.I. | 登録日 | 2022-11-04 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4. Structure, 31, 2023
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8BWQ
| Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with topotecan) | 分子名称: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, ATP-binding cassette sub-family C member 4 | 著者 | Raj, I, Bloch, M, Pape, T.H, Taylor, N.M.I. | 登録日 | 2022-12-07 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4. Structure, 31, 2023
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8BWP
| Cryo-EM structure of nanodisc-reconstituted wildtype human MRP4 (in complex with methotrexate) | 分子名称: | ATP-binding cassette sub-family C member 4, METHOTREXATE | 著者 | Raj, I, Bloch, M, Pape, T.H, Taylor, N.M.I. | 登録日 | 2022-12-07 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural and mechanistic basis of substrate transport by the multidrug transporter MRP4. Structure, 31, 2023
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