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1JBE
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BU of 1jbe by Molmil
1.08 A Structure of apo-Chey reveals meta-active conformation
分子名称: Chemotaxis protein CheY, GLYCEROL, SULFATE ION
著者Simonovic, M, Volz, K.
登録日2001-06-04
公開日2001-08-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献A distinct meta-active conformation in the 1.1-A resolution structure of wild-type ApoCheY.
J.Biol.Chem., 276, 2001
1M93
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BU of 1m93 by Molmil
1.65 A Structure of Cleaved Viral Serpin CRMA
分子名称: PHOSPHATE ION, Serine proteinase inhibitor 2
著者Simonovic, M, Gettins, P.G.W, Volz, K.
登録日2002-07-26
公開日2003-08-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition
Protein Sci., 9, 2000
1IMV
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BU of 1imv by Molmil
2.85 A crystal structure of PEDF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PIGMENT EPITHELIUM-DERIVED FACTOR
著者Simonovic, M, Gettins, P.G.W, Volz, K.
登録日2001-05-11
公開日2001-09-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor.
Proc.Natl.Acad.Sci.USA, 98, 2001
1J8E
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BU of 1j8e by Molmil
Crystal structure of ligand-binding repeat CR7 from LRP
分子名称: CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1
著者Simonovic, M, Dolmer, K, Huang, W, Strickland, D.K, Volz, K, Gettins, P.G.W.
登録日2001-05-21
公開日2001-12-19
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. Comparison with related domains from the LRP and the LDL receptor.
Biochemistry, 40, 2001
3CME
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BU of 3cme by Molmil
The Structure of CA and CCA-PHE-CAP-BIO Bound to the Large Ribosomal Subunit of Haloarcula Marismortui
分子名称: 50S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Simonovic, M, Steitz, T.A.
登録日2008-03-21
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
3CMA
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BU of 3cma by Molmil
The structure of CCA and CCA-Phe-Cap-Bio bound to the large ribosomal subunit of Haloarcula marismortui
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Simonovic, M, Steitz, T.A.
登録日2008-03-21
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
1C8O
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BU of 1c8o by Molmil
2.9 A STRUCTURE OF CLEAVED VIRAL SERPIN CRMA
分子名称: ICE INHIBITOR
著者Simonovic, M, Gettins, P.G.W, Volz, K.
登録日2000-06-01
公開日2000-09-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition.
Protein Sci., 9, 2000
2FOT
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BU of 2fot by Molmil
Crystal structure of the complex between calmodulin and alphaII-spectrin
分子名称: CALCIUM ION, Calmodulin, alpha-II spectrin Spectrin
著者Simonovic, M, Zhang, Z, Cianci, C.D, Steitz, T.A, Morrow, J.S.
登録日2006-01-13
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of the calmodulin alphaII-spectrin complex provides insight into the regulation of cell plasticity.
J.Biol.Chem., 281, 2006
3EDU
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BU of 3edu by Molmil
Crystal structure of the ankyrin-binding domain of human erythroid spectrin
分子名称: Spectrin beta chain, erythrocyte
著者Simonovic, M, Stabach, P, Simonovic, I, Steitz, T.A, Morrow, J.S.
登録日2008-09-03
公開日2009-02-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of the ankyrin-binding site of {beta}-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties
Blood, 113, 2009
4EO4
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BU of 4eo4 by Molmil
Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex with seryl sulfamoyl adenylate
分子名称: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, Threonine--tRNA ligase, mitochondrial, ...
著者Peterson, K.M, Ling, J, Simonovic, I, Soll, D, Simonovic, M.
登録日2012-04-13
公開日2012-07-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献The mechanism of pre-transfer editing in yeast mitochondrial threonyl-tRNA synthetase.
J.Biol.Chem., 287, 2012
4ZDO
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BU of 4zdo by Molmil
The crystal structure of T325S mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, PHOSPHATE ION, ...
著者French, R.L, Simonovic, M.
登録日2015-04-17
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
4ZDL
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BU of 4zdl by Molmil
The crystal structure of the T325S mutant of the human holo SepSecS
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, CITRATE ANION, O-phosphoseryl-tRNA(Sec) selenium transferase
著者French, R.L, Simonovic, M.
登録日2015-04-17
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.
Sci Rep, 6, 2016
5M11
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BU of 5m11 by Molmil
Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.
分子名称: CACODYLATE ION, CALCIUM ION, CHLORIDE ION, ...
著者Lasica, A.M, Goulas, T, Mizgalska, D, Zhou, X, Ksiazek, M, Madej, M, Guo, Y, Guevara, T, Nowak, M, Potempa, B, Goel, A, Sztukowska, M, Prabhakar, A.T, Bzowska, M, Widziolek, M, Thogersen, I.B, Enghild, J.J, Simonian, M, Kulczyk, A.W, Nguyen, K.-A, Potempa, J, Gomis-Ruth, F.X.
登録日2016-10-07
公開日2016-11-09
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.
Sci Rep, 6, 2016
5IZL
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BU of 5izl by Molmil
The crystal structure of human eEFSec in complex with GDPCP
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Selenocysteine-specific elongation factor
著者Dobosz-Bartoszek, M, Simonovic, M.
登録日2016-03-25
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
5IZM
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BU of 5izm by Molmil
The crystal structure of human eEFSec in complex with GDPNP
分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Selenocysteine-specific elongation factor
著者Dobosz-Bartoszek, M, Otwinowski, Z, Simonovic, M.
登録日2016-03-25
公開日2016-10-12
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
5IZK
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The crystal structure of human eEFSec in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Selenocysteine-specific elongation factor
著者Dobosz-Bartoszek, M, Simonovic, M.
登録日2016-03-25
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
8G9Z
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BU of 8g9z by Molmil
High-resolution crystal structure of the human selenomethionine-derived SepSecS-tRNASec complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, ...
著者Puppala, A, Simonovic, M, Castillo Suchkou, J.
登録日2023-02-22
公開日2023-04-05
最終更新日2023-05-17
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans.
Nucleic Acids Res., 51, 2023
7ZJX
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BU of 7zjx by Molmil
Rabbit 80S ribosome programmed with SECIS and SBP2
分子名称: 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ...
著者Hilal, T, Simonovic, M, Spahn, C.M.T.
登録日2022-04-12
公開日2022-09-07
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Science, 376, 2022
6O0X
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Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium
分子名称: 3' product of target strand DNA, 5' product of target strand DNA, CRISPR-associated endonuclease Cas9/Csn1, ...
著者Zhu, X, Clarke, R, Puppala, A.K, Chittori, S, Merk, A, Merrill, B.J, Simonovic, M, Subramaniam, S.
登録日2019-02-17
公開日2019-07-10
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Nat.Struct.Mol.Biol., 26, 2019
6O0Z
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BU of 6o0z by Molmil
Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium
分子名称: CRISPR-associated endonuclease Cas9/Csn1, non-target strand DNA, single guide RNA, ...
著者Zhu, X, Clarke, R, Puppala, A.K, Chittori, S, Merk, A, Merrill, B.J, Simonovic, M, Subramaniam, S.
登録日2019-02-17
公開日2019-07-10
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Nat.Struct.Mol.Biol., 26, 2019
6O0Y
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BU of 6o0y by Molmil
Conformational states of Cas9-sgRNA-DNA ternary complex in the presence of magnesium
分子名称: 3' product of target strand DNA, 5' product of target strand DNA, CRISPR-associated endonuclease Cas9/Csn1, ...
著者Zhu, X, Clarke, R, Puppala, A.K, Chittori, S, Merk, A, Merrill, B.J, Simonovic, M, Subramaniam, S.
登録日2019-02-17
公開日2019-07-10
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Nat.Struct.Mol.Biol., 26, 2019
7ZJW
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BU of 7zjw by Molmil
Rabbit 80S ribosome as it decodes the Sec-UGA codon
分子名称: 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ...
著者Hilal, T, Simonovic, M, Spahn, C.M.T.
登録日2022-04-12
公開日2022-10-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Science, 376, 2022
3UGQ
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Crystal structure of the apo form of the yeast mitochondrial threonyl-tRNA synthetase determined at 2.1 Angstrom resolution
分子名称: POTASSIUM ION, SULFATE ION, Threonyl-tRNA synthetase, ...
著者Peterson, K.M, Ling, J, Simonovic, I, Cho, C, Soll, D, Simonovic, M.
登録日2011-11-02
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UH0
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Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex with threonyl sulfamoyl adenylate
分子名称: 5'-O-(N-(L-THREONYL)-SULFAMOYL)ADENOSINE, SULFATE ION, Threonyl-tRNA synthetase, ...
著者Peterson, K.M, Ling, J, Simonovic, I, Cho, C, Soll, D, Simonovic, M.
登録日2011-11-03
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UGT
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Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase - orthorhombic crystal form
分子名称: Threonyl-tRNA synthetase, mitochondrial, ZINC ION
著者Peterson, K.M, Ling, J, Simonovic, I, Cho, C, Soll, D, Simonovic, M.
登録日2011-11-02
公開日2012-02-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment.
Proc.Natl.Acad.Sci.USA, 109, 2012

 

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