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4JRD
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BU of 4jrd by Molmil
Crystal structure of the parallel double-stranded helix of poly(A) RNA
分子名称: AMMONIUM ION, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
著者Safaee, N, Noronha, A.M, Kozlov, G, Rodionov, D, Wilds, C.J, Sheldrick, G.M, Gehring, K.
登録日2013-03-21
公開日2013-06-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structure of the parallel duplex of poly(A) RNA: evaluation of a 50 year-old prediction.
Angew.Chem.Int.Ed.Engl., 52, 2013
4F02
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BU of 4f02 by Molmil
Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A)
分子名称: Eukaryotic translation initiation factor 4 gamma 1, Polyadenylate-binding protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
著者Safaee, N, Kozlov, G, Gehring, K.B.
登録日2012-05-03
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4F26
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BU of 4f26 by Molmil
Crystal structure of the second RRM domain of human PABPC1 a pH 9.0
分子名称: Polyadenylate-binding protein 1
著者Kozlov, G, Safaee, N, Gehring, K.
登録日2012-05-07
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4F25
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BU of 4f25 by Molmil
Crystal structure of the second RRM domain of human PABPC1 at pH 6.0
分子名称: Polyadenylate-binding protein 1
著者Kozlov, G, Safaee, N, Gehring, K.
登録日2012-05-07
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
5VXQ
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BU of 5vxq by Molmil
X-Ray crystallography structure of the parallel stranded duplex formed by 5-rA5-dA-rA5
分子名称: AMMONIUM ION, DNA/RNA (5'-R(*AP*AP*AP*AP*A)-D(P*A)-R(P*AP*AP*AP*AP*A)-3')
著者Xie, J, Chen, Y, Wei, X, Kozlov, G, Gehring, K.
登録日2017-05-23
公開日2017-08-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.002 Å)
主引用文献Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA.
Nucleic Acids Res., 45, 2017
5TGG
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BU of 5tgg by Molmil
Solution structure of parallel stranded adenosine duplex
分子名称: RNA/DNA (5'-D(P*T)-R(*(A2M)P*(A2M)P*(A2M)P*(A2M))-D(P*A)-R(P*(A2M)P*(A2M)P*(A2M))-3')
著者Denisov, A, Noronha, A, Gehring, K, Wilds, C.
登録日2016-09-27
公開日2017-08-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA.
Nucleic Acids Res., 45, 2017
3KTR
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BU of 3ktr by Molmil
Structural basis of ataxin-2 recognition by poly(A)-binding protein
分子名称: Ataxin-2, CADMIUM ION, Polyadenylate-binding protein 1, ...
著者Kozlov, G, Gehring, K.
登録日2009-11-25
公開日2010-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein.
J.Biol.Chem., 285, 2010
3KTP
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BU of 3ktp by Molmil
Structural basis of GW182 recognition by poly(A)-binding protein
分子名称: Polyadenylate-binding protein 1, Trinucleotide repeat-containing gene 6C protein
著者Kozlov, G, Gehring, K.
登録日2009-11-25
公開日2010-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein.
J.Biol.Chem., 285, 2010
6BN8
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BU of 6bn8 by Molmil
Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET55 PROTAC.
分子名称: Bromodomain-containing protein 4, DNA damage-binding protein 1,DNA damage-binding protein 1, Protein cereblon, ...
著者Nowak, R.P, DeAngelo, S.L, Buckley, D, Bradner, J.E, Fischer, E.S.
登録日2017-11-16
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.990035 Å)
主引用文献Plasticity in binding confers selectivity in ligand-induced protein degradation.
Nat. Chem. Biol., 14, 2018
6BN9
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BU of 6bn9 by Molmil
Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET70 PROTAC
分子名称: Bromodomain-containing protein 4, DNA damage-binding protein 1,DNA damage-binding protein 1, Protein cereblon, ...
著者Nowak, R.P, DeAngelo, S.L, Buckley, D, Bradner, J.E, Fischer, E.S.
登録日2017-11-16
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.382 Å)
主引用文献Plasticity in binding confers selectivity in ligand-induced protein degradation.
Nat. Chem. Biol., 14, 2018
6BOY
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BU of 6boy by Molmil
Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET6 PROTAC.
分子名称: 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(8-{[({2-[(3S)-2,6-dioxopiperidin-3-yl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}oxy)acetyl]amino}octyl)acetamide, Bromodomain-containing protein 4, DNA damage-binding protein 1, ...
著者Nowak, R.P, DeAngelo, S.L, Buckley, D, Bradner, J.E, Fischer, E.S.
登録日2017-11-21
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.33 Å)
主引用文献Plasticity in binding confers selectivity in ligand-induced protein degradation.
Nat. Chem. Biol., 14, 2018
6BN7
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BU of 6bn7 by Molmil
Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET23 PROTAC.
分子名称: Bromodomain-containing protein 4, DNA damage-binding protein 1, Protein cereblon, ...
著者Nowak, R.P, DeAngelo, S.L, Buckley, D, Bradner, J.E, Fischer, E.S.
登録日2017-11-16
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.501 Å)
主引用文献Plasticity in binding confers selectivity in ligand-induced protein degradation.
Nat. Chem. Biol., 14, 2018
6BNB
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BU of 6bnb by Molmil
Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET57 PROTAC
分子名称: Bromodomain-containing protein 4, DNA damage-binding protein 1, Protein cereblon, ...
著者Nowak, R.P, DeAngelo, S.L, Buckley, D, Ishoey, M, He, Z, Zhang, T, Bradner, J.E, Fischer, E.S.
登録日2017-11-16
公開日2018-05-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (6.343 Å)
主引用文献Plasticity in binding confers selectivity in ligand-induced protein degradation.
Nat. Chem. Biol., 14, 2018

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