3KTR

Structural basis of ataxin-2 recognition by poly(A)-binding protein

Summary for 3KTR

Entry DOI	10.2210/pdb3ktr/pdb
Related	3KTP
Descriptor	Polyadenylate-binding protein 1, Ataxin-2, CADMIUM ION, ... (5 entities in total)
Functional Keywords	protein-protein complex, acetylation, alternative splicing, cytoplasm, methylation, mrna processing, mrna splicing, nucleus, phosphoprotein, rna-binding, spliceosome, neurodegeneration, parkinsonism, polymorphism, spinocerebellar ataxia, triplet repeat expansion, protein binding
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P11940 Cytoplasm (By similarity): Q99700
Total number of polymer chains	2
Total formula weight	11665.54
Authors	Kozlov, G.,Gehring, K. (deposition date: 2009-11-25, release date: 2010-02-23, Last modification date: 2023-09-06)
Primary citation	Kozlov, G.,Safaee, N.,Rosenauer, A.,Gehring, K. Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein. J.Biol.Chem., 285:13599-13606, 2010 Cited by PubMed: 20181956 DOI: 10.1074/jbc.M109.089540 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation