4UHU
 
 | | W229D mutant of the last common ancestor of Gram-negative bacteria (GNCA) beta-lactamase class A | | 分子名称: | ACETATE ION, FORMIC ACID, GNCA LACTAMASE W229D | | 著者 | Gavira, J.A, Risso, V.A, Martinez-Rodriguez, S, Sanchez-Ruiz, J.M. | | 登録日 | 2015-03-25 | | 公開日 | 2016-04-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.305 Å) | | 主引用文献 | De novo active sites for resurrected Precambrian enzymes.
Nat Commun, 8, 2017
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3VCY
 | | Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase), from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin. | | 分子名称: | GLYCEROL, PHOSPHATE ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, ... | | 著者 | Bensen, D.C, Rodriguez, S, Nix, J, Cunningham, M.L, Tari, L.W. | | 登録日 | 2012-01-04 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.925 Å) | | 主引用文献 | Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase) from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin.
Acta Crystallogr.,Sect.F, 68, 2012
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3N5F
 | | Crystal Structure of L-N-carbamoylase from Geobacillus stearothermophilus CECT43 | | 分子名称: | CACODYLATE ION, COBALT (II) ION, ISOPROPYL ALCOHOL, ... | | 著者 | Garcia-Pino, A, Martinez-Rodriguez, S, Gavira, J.A. | | 登録日 | 2010-05-25 | | 公開日 | 2011-05-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Mutational and structural analysis of L-N-carbamoylase reveals new insights into a peptidase m20/m25/m40 family member.
J.Bacteriol., 194, 2012
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3DC8
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6YC5
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6YBI
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6YBO
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6YBX
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6YBR
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6YBF
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3EBA
 | | CAbHul6 FGLW mutant (humanized) in complex with human lysozyme | | 分子名称: | CAbHul6, Lysozyme C, SULFATE ION | | 著者 | Loris, R, Vincke, C, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K. | | 登録日 | 2008-08-27 | | 公開日 | 2008-12-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold
J.Biol.Chem., 284, 2009
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3EAK
 | | NbBCII10 humanized (FGLA mutant) | | 分子名称: | NbBCII10-FGLA, SULFATE ION | | 著者 | Vincke, C, Loris, R, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K. | | 登録日 | 2008-08-26 | | 公開日 | 2008-12-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold.
J.Biol.Chem., 2008
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8QME
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4HX3
 | | Crystal structure of Streptomyces caespitosus sermetstatin in complex with S. caespitosus snapalysin | | 分子名称: | Extracellular small neutral protease, GLYCEROL, Neutral proteinase inhibitor ScNPI, ... | | 著者 | Trillo-Muyo, S, Martinez-Rodriguez, S, Arolas, J.L, Gomis-Ruth, F.X. | | 登録日 | 2012-11-09 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Mechanism of action of a Janus-faced single-domain protein inhibitor simultaneously targeting two peptidase classes
CHEM SCI, 4, 2013
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3DIE
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6YRS
 | | Structure of a new variant of GNCA ancestral beta-lactamase | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Gavira, J.A, Risso, V, Martinez-Rodriguez, S, Sanchez-Ruiz, J.M, Modi, T, Ozkan, S.B. | | 登録日 | 2020-04-20 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Hinge-shift mechanism as a protein design principle for the evolution of beta-lactamases from substrate promiscuity to specificity.
Nat Commun, 12, 2021
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4HX2
 | | Crystal structure of Streptomyces caespitosus sermetstatin in complex with Bacillus licheniformis subtilisin | | 分子名称: | (2R,2'R)-3,3'-oxydipropane-1,2-diol, ACETATE ION, CACODYLATE ION, ... | | 著者 | Trillo-Muyo, S, Martinez-Rodriguez, S, Arolas, J.L, Gomis-Ruth, F.X. | | 登録日 | 2012-11-09 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Mechanism of action of a Janus-faced single-domain protein inhibitor simultaneously targeting two peptidase classes
CHEM SCI, 4, 2013
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4HWX
 | | Crystal structure of Streptomyces caespitosus sermetstatin | | 分子名称: | ACETATE ION, GLYCEROL, Neutral proteinase inhibitor ScNPI | | 著者 | Trillo-Muyo, S, Martinez-Rodriguez, S, Arolas, J.L, Gomis-Ruth, F.X. | | 登録日 | 2012-11-09 | | 公開日 | 2012-12-05 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanism of action of a Janus-faced single-domain protein inhibitor simultaneously targeting two peptidase classes
CHEM SCI, 4, 2013
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7PTH
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7APN
 | | Structure of Lipase TL from bulk agarose grown crystal | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Lipase, ... | | 著者 | Gavira, J.A, Martinez-Rodriguez, S, Fernande-Penas, R, Verdugo-Escamilla, C. | | 登録日 | 2020-10-19 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Production of Cross-Linked Lipase Crystals at a Preparative Scale.
Cryst.Growth Des., 21, 2021
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7APP
 | | Structure of Lipase TL from capillary grown crystal in the presence of agarose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FORMIC ACID, Lipase, ... | | 著者 | Gavira, J.A, Martinez-Rodriguez, S, Fernande-Penas, R, Verdugo-Escamilla, C. | | 登録日 | 2020-10-19 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Production of Cross-Linked Lipase Crystals at a Preparative Scale.
Cryst.Growth Des., 21, 2021
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7A6G
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5FQM
 | | Last common ancestor of Gram Negative Bacteria (GNCA) Class A beta- lactamase | | 分子名称: | GLYCEROL, GNCA BETA LACTAMASE, SULFATE ION | | 著者 | Martinez Rodriguez, S, Gavira, J.A, Risso, V.A, Sanchez Ruiz, J.M. | | 登録日 | 2015-12-12 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | De novo active sites for resurrected Precambrian enzymes.
Nat Commun, 8, 2017
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7PTJ
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6G5Z
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