7PTJ

C54S mutant of choline-sulfatase from E. meliloti CECT4857 bound to HEPES

Summary for 7PTJ

Entry DOI	10.2210/pdb7ptj/pdb
Related	6G5Z 6G60
Descriptor	Choline sulfatase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, ... (6 entities in total)
Functional Keywords	choline, sulfatase, sulfate, hydrolase
Biological source	Rhizobium meliloti (Ensifer meliloti, Sinorhizobium meliloti)
Total number of polymer chains	4
Total formula weight	242148.46
Authors	Gavira, J.A.,Martinez-Rodriguez, S. (deposition date: 2021-09-27, release date: 2022-08-03, Last modification date: 2024-01-31)
Primary citation	Gavira, J.A.,Camara-Artigas, A.,Neira, J.L.,Torres de Pinedo, J.M.,Sanchez, P.,Ortega, E.,Martinez-Rodriguez, S. Structural insights into choline-O-sulfatase reveal the molecular determinants for ligand binding. Acta Crystallogr D Struct Biol, 78:669-682, 2022 Cited by PubMed: 35503214 DOI: 10.1107/S2059798322003709 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation