3VCY

Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase), from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin.

Summary for 3VCY

Entry DOI	10.2210/pdb3vcy/pdb
Descriptor	UDP-N-acetylglucosamine 1-carboxyvinyltransferase, [(1R)-1-hydroxypropyl]phosphonic acid, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ... (6 entities in total)
Functional Keywords	mura, fosfomycin, peptidoglycan, amino sugar and nucleotide sugar metabolism, peptidoglycan biosynthesis, cytosol, transferase-antibiotic complex, transferase/antibiotic
Biological source	Vibrio fischeri
Cellular location	Cytoplasm (By similarity): B5F9P4
Total number of polymer chains	4
Total formula weight	186938.77
Authors	Bensen, D.C.,Rodriguez, S.,Nix, J.,Cunningham, M.L.,Tari, L.W. (deposition date: 2012-01-04, release date: 2012-04-11, Last modification date: 2023-09-13)
Primary citation	Bensen, D.C.,Rodriguez, S.,Nix, J.,Cunningham, M.L.,Tari, L.W. Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase) from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin. Acta Crystallogr.,Sect.F, 68:382-385, 2012 Cited by PubMed: 22505403 DOI: 10.1107/S1744309112006720 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.925 Å)

Structure validation