3VCY

Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase), from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	polymer	430	45800.2	4	UniProt (B5F9P4) Pfam (PF00275)	Vibrio fischeri	Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT
2	E, J, O, T (A, B, C, D)	[(1R)-1-hydroxypropyl]phosphonic acid	non-polymer		140.1	4	Chemie (FFQ)
3	F, I, M, Q (A, B, C, D)	URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE	non-polymer		607.4	4	Chemie (UD1)
4	G, K, N, R (A, B, C, D)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
5	H, L, P, S (A, B, C, D)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
6	U, V, W, X (A, B, C, D)	water	water		18.0	1171	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 422 (UniProt: B5F9P4)

PDB	External Database	Details
Asp 2	Tyr 2	SEE REMARK 999
Leu 423	-	expression tag
Glu 424	-	expression tag
His 425	-	expression tag
His 426	-	expression tag
His 427	-	expression tag
His 428	-	expression tag
His 429	-	expression tag
His 430	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	183200.8
Non-Polymers*	Number of molecules	16
	Total formula weight	3738.0
All*	Total formula weight	186938.8

*Water molecules are not included.