5A6I
 
 | | V122I Transthyretin structure in complex with Tolcalpone | | 分子名称: | TRANSTHYRETIN, Tolcapone | | 著者 | Reverter, D, Gallego, P, Santana, R, Ventura, S. | | 登録日 | 2015-06-26 | | 公開日 | 2016-02-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Repositioning Tolcapone as a Potent Inhibitor of Transthyretin Amyloidogenesis and its Associated Cellular Toxicity
Nat.Commun., 7, 2016
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6RO9
 | | Human spectrin SH3 domain D48G, E7V, K60V | | 分子名称: | Spectrin alpha, non-erythrocytic 1 | | 著者 | Reverter, D, Navarro, S, Ventura, S. | | 登録日 | 2019-05-10 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.814 Å) | | 主引用文献 | Human spectrin SH3 domain D48G, E7V, K60V
To Be Published
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7AL8
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8OI3
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1DTV
 | | NMR STRUCTURE OF THE LEECH CARBOXYPEPTIDASE INHIBITOR (LCI) | | 分子名称: | CARBOXYPEPTIDASE INHIBITOR | | 著者 | Reverter, D, Fernandez-Catalan, C, Bode, W, Holak, T.A, Aviles, F.X. | | 登録日 | 2000-01-13 | | 公開日 | 2000-07-19 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Nat.Struct.Biol., 7, 2000
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1DTD
 | | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE LEECH CARBOXYPEPTIDASE INHIBITOR AND THE HUMAN CARBOXYPEPTIDASE A2 (LCI-CPA2) | | 分子名称: | CARBOXYPEPTIDASE A2, GLUTAMIC ACID, METALLOCARBOXYPEPTIDASE INHIBITOR, ... | | 著者 | Reverter, D, Fernandez-Catalan, C, Bode, W, Holak, T.A, Aviles, F.X. | | 登録日 | 2000-01-12 | | 公開日 | 2000-07-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Nat.Struct.Biol., 7, 2000
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1Z5S
 | | Crystal structure of a complex between UBC9, SUMO-1, RANGAP1 and NUP358/RANBP2 | | 分子名称: | Ran GTPase-activating protein 1, Ran-binding protein 2, Ubiquitin-conjugating enzyme E2 I, ... | | 著者 | Reverter, D, Lima, C.D. | | 登録日 | 2005-03-19 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex.
Nature, 435, 2005
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1XT9
 | | Crystal Structure of Den1 in complex with Nedd8 | | 分子名称: | Neddylin, Sentrin-specific protease 8 | | 著者 | Reverter, D, Wu, K, Erdene, T.G, Pan, Z.Q, Wilkinson, K.D, Lima, C.D. | | 登録日 | 2004-10-21 | | 公開日 | 2004-12-21 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a Complex between Nedd8 and the Ulp/Senp Protease Family Member Den1.
J.Mol.Biol., 345, 2005
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1TGZ
 | | Structure of human Senp2 in complex with SUMO-1 | | 分子名称: | SULFATE ION, Sentrin-specific protease 2, Ubiquitin-like protein SMT3C | | 著者 | Reverter, D, Lima, C.D. | | 登録日 | 2004-05-31 | | 公開日 | 2004-09-14 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A basis for SUMO protease specificity provided by analysis of human Senp2 and a
Senp2-SUMO complex
Structure, 12, 2004
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1TH0
 | | Structure of human Senp2 | | 分子名称: | Sentrin-specific protease 2 | | 著者 | Reverter, D, Lima, C.D. | | 登録日 | 2004-05-31 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A basis for SUMO protease specificity provided by analysis of human Senp2 and a
Senp2-SUMO complex
Structure, 12, 2004
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2IO3
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2IO1
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2IO0
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2IO2
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7R2E
 | | Structure of human Senp7 with SUMO2 | | 分子名称: | Sentrin-specific protease 7, Small ubiquitin-related modifier 3, prop-2-en-1-amine | | 著者 | Reverter, D, Li, Y. | | 登録日 | 2022-02-04 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structural Basis for the SUMO2 Isoform Specificity of SENP7.
J.Mol.Biol., 434, 2022
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7P99
 | | Structure of human USPL1 in complex with SUMO2 | | 分子名称: | SUMO-specific isopeptidase USPL1, Small ubiquitin-related modifier, ZINC ION | | 著者 | Reverter, D, Ying, L. | | 登録日 | 2021-07-26 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for the SUMO protease activity of the atypical ubiquitin-specific protease USPL1.
Nat Commun, 13, 2022
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5O71
 | | Crystal structure of human USP25 | | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 25 | | 著者 | Reverter, D, Liu, B. | | 登録日 | 2017-06-07 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.283 Å) | | 主引用文献 | A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25.
Nat Commun, 9, 2018
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1UWY
 | | Crystal structure of human carboxypeptidase M | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE M, ZINC ION | | 著者 | Maskos, K, Reverter, D, Bode, W. | | 登録日 | 2004-02-17 | | 公開日 | 2004-04-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal Structure of Human Carboxypeptidase M, a Membrane-Bound Enzyme that Regulates Peptide Hormone Activity
J.Mol.Biol., 338, 2004
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6EOA
 | | Crystal Structure of HAL3 from Cryptococcus neoformans | | 分子名称: | FLAVIN MONONUCLEOTIDE, Phosphopantothenoylcysteine decarboxylase | | 著者 | Reverter, D, Zhang, C, Molero, C, Arino, J. | | 登録日 | 2017-10-09 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Characterization of the atypical Ppz/Hal3 phosphatase system from the pathogenic fungus Cryptococcus neoformans.
Mol.Microbiol., 111, 2019
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4D7B
 | | Structure of human transthyretin in complex with Tolcapone | | 分子名称: | TRANSTHYRETIN, Tolcapone | | 著者 | Gallego, P, Sant'anna, R.O, Ventura, S, Reverter, D. | | 登録日 | 2014-11-21 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Repositioning Tolcapone as a Potent Inhibitor of Transthyretin Amyloidogenesis and its Associated Cellular Toxicity
Nat.Commun., 7, 2016
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1AYE
 | | HUMAN PROCARBOXYPEPTIDASE A2 | | 分子名称: | PROCARBOXYPEPTIDASE A2, ZINC ION | | 著者 | Garcia-Saez, I, Reverte, D, Vendrell, J, Aviles, F.X, Coll, M. | | 登録日 | 1997-11-03 | | 公開日 | 1999-01-13 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen.
EMBO J., 16, 1997
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7ZQ7
 | | Structure of RpF-1 | | 分子名称: | Crotonase/enoyl-CoA hydratase family protein | | 著者 | Sanchez-Alba, L, Reverter, D, Conchillo, O, Yero, D, Daura, X, Gibert, I. | | 登録日 | 2022-04-29 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of RpF-1
To Be Published
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6TXW
 | | V30G Transthyretin structure in complex with Tolcalpone | | 分子名称: | Tolcapone, Transthyretin | | 著者 | Varejao, N, Reverter, D, Pinheiro, F, Pallares, I, Ventura, S. | | 登録日 | 2020-01-14 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.153 Å) | | 主引用文献 | Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis.
Febs J., 288, 2021
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6TXV
 | | A25T Transthyretin structure in complex with Tolcalpone | | 分子名称: | Tolcapone, Transthyretin | | 著者 | Varejao, N, Reverter, D, Pinheiro, F, Pallares, I, Ventura, S. | | 登録日 | 2020-01-14 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis.
Febs J., 288, 2021
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7P47
 | | Structure of the E3 ligase Smc5/Nse2 in complex with Ubc9-SUMO thioester mimetic | | 分子名称: | E3 SUMO-protein ligase MMS21, SUMO-conjugating enzyme UBC9, Structural maintenance of chromosomes protein 5, ... | | 著者 | Lascorz, J, Varejao, N, Reverter, D. | | 登録日 | 2021-07-09 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.314 Å) | | 主引用文献 | Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs.
Nat Commun, 12, 2021
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