6MHE
 
 | | Galphai3 co-crystallized with KB752 | | 分子名称: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(k) subunit alpha, ... | | 著者 | Rees, S.D, Kalogriopoulos, N.A, Ngo, T, Kopcho, N, Ilatovskiy, A, Sun, N, Komives, E, Chang, G, Ghosh, P, Kufareva, I. | | 登録日 | 2018-09-17 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for GPCR-independent activation of heterotrimeric Gi proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6MHF
 | | Galphai3 co-crystallized with GIV/Girdin | | 分子名称: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, Girdin, ... | | 著者 | Rees, S.D, Kalogriopoulos, N.A, Ngo, T, Kopcho, N, Ilatovskiy, A, Sun, N, Komives, E, Chang, G, Ghosh, P, Kufareva, I. | | 登録日 | 2018-09-17 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for GPCR-independent activation of heterotrimeric Gi proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6MNJ
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7MHU
 | | Sialidase24 apo | | 分子名称: | Exo-alpha-sialidase | | 著者 | Rees, S.D, Chang, G.A. | | 登録日 | 2021-04-15 | | 公開日 | 2022-02-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Computational models in the service of X-ray and cryo-electron microscopy structure determination.
Proteins, 89, 2021
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9NLP
 | | HIV-1 Reverse Transcriptase with New Non-Nucleoside Reverse Transcriptase Inhibitor 12126065 | | 分子名称: | 4-({5-amino-1-[6-(2-cyanoethyl)naphthalene-1-sulfonyl]-1H-1,2,4-triazol-3-yl}amino)-2-chlorobenzonitrile, Reverse transcriptase p51 subunit, Reverse transcriptase p66 subunit | | 著者 | Young, M.A, Lane, T.R, Raman, R, Nelson, J.A.E, Riabova, O, Kazakova, E, Monakhova, N, Tsedilin, A, Rees, S.D, Quinnell, D, Chang, G, Ekins, S. | | 登録日 | 2025-03-03 | | 公開日 | 2025-05-07 | | 最終更新日 | 2025-05-21 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Cryo-EM Structure of HIV-1 Reverse Transcriptase with N -Phenyl-1-(phenylsulfonyl)-1 H -1,2,4-triazol-3-amine: A New HIV-1 Non-nucleoside Inhibitor.
Acs Infect Dis., 11, 2025
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4XWK
 | | P-glycoprotein co-crystallized with BDE-100 | | 分子名称: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, Multidrug resistance protein 1A | | 著者 | McGrath, A.P, Rees, S.D, Chang, G. | | 登録日 | 2015-01-28 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure.
Sci Adv, 2, 2016
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6MRV
 | | Sialidase26 co-crystallized with DANA | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Sialidase26 | | 著者 | Zaramela, L.S, Martino, C, Alisson-Silva, F, Rees, S.D, Diaz, S.L, Chuzel, L, Ganatra, M.B, Taron, C.H, Zuniga, C, Chang, G, Varki, A, Zengler, K. | | 登録日 | 2018-10-15 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 4, 2019
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6MYV
 | | Sialidase26 co-crystallized with DANA-Gc | | 分子名称: | 2,6-anhydro-3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-L-altro-non-2-enonic acid, Sialidase26 | | 著者 | Zaramela, L.S, Martino, C, Alisson-Silva, F, Rees, S.D, Diaz, S.L, Chuzel, L, Ganatra, M.B, Taron, C.H, Zuniga, C, Huang, J, Siegel, D, Chang, G, Varki, A, Zengler, K. | | 登録日 | 2018-11-02 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 4, 2019
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6MRX
 | | Sialidase26 apo | | 分子名称: | Sialidase26 | | 著者 | Zaramela, L.S, Martino, C, Alisson-Silva, F, Rees, S.D, Diaz, S.L, Chuzel, L, Ganatra, M.B, Taron, C.H, Zuniga, C, Chang, G, Varki, A, Zengler, K. | | 登録日 | 2018-10-15 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 4, 2019
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9NFK
 | | Tuna P-glycoprotein Apo Conformation 3 | | 分子名称: | Permeability Glycoprotein (P-gp) | | 著者 | Young, M.A, Rees, S.D, Nicklisch, S.C.T, Stowell, M, Hamdoun, A, Chang, G. | | 登録日 | 2025-02-21 | | 公開日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | | 主引用文献 | Cryo-EM Structures of Apo and DDT-Bound P-Glycoprotein in Yellowfin Tuna.
Environ Sci Technol., 2025
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9NFL
 | | Tuna P-glycoprotein Apo Conformation 4 | | 分子名称: | Permeability Glycoprotein (P-gp) | | 著者 | Young, M.A, Rees, S.D, Nicklisch, S.C.T, Stowell, M, Hamdoun, A, Chang, G. | | 登録日 | 2025-02-21 | | 公開日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | | 主引用文献 | Cryo-EM Structures of Apo and DDT-Bound P-Glycoprotein in Yellowfin Tuna.
Environ Sci Technol., 2025
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9NFM
 | | Tuna P-glycoprotein bound to DDT | | 分子名称: | 1-chloranyl-4-[2,2,2-tris(chloranyl)-1-(4-chlorophenyl)ethyl]benzene, Permeability Glycoprotein (P-gp) | | 著者 | Young, M.A, Rees, S.D, Nicklisch, S.C.T, Stowell, M, Hamdoun, A, Chang, G. | | 登録日 | 2025-02-21 | | 公開日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Cryo-EM Structures of Apo and DDT-Bound P-Glycoprotein in Yellowfin Tuna.
Environ Sci Technol., 2025
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9NFJ
 | | Tuna P-glycoprotein Apo Conformation 2 | | 分子名称: | Permeability Glycoprotein (P-gp) | | 著者 | Young, M.A, Rees, S.D, Nicklisch, S.C.T, Stowell, M, Hamdoun, A, Chang, G. | | 登録日 | 2025-02-21 | | 公開日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | | 主引用文献 | Cryo-EM Structures of Apo and DDT-Bound P-Glycoprotein in Yellowfin Tuna.
Environ Sci Technol., 2025
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9NFI
 | | Tuna P-glycoprotein Apo Conformation 1 | | 分子名称: | Permeability Glycoprotein (P-gp) | | 著者 | Young, M.A, Rees, S.D, Nicklisch, S.C.T, Stowell, M, Hamdoun, A, Chang, G, Center for Structures of Membrane Proteins (CSMP) | | 登録日 | 2025-02-21 | | 公開日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | | 主引用文献 | Cryo-EM Structures of Apo and DDT-Bound P-Glycoprotein in Yellowfin Tuna.
Environ Sci Technol., 2025
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4Q9H
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4Q9J
 | | P-glycoprotein cocrystallised with QZ-Val | | 分子名称: | Multidrug resistance protein 1A, N-{[5-AMINO-1-(5-O-PHOSPHONO-BETA-D-ARABINOFURANOSYL)-1H-IMIDAZOL-4-YL]CARBONYL}-L-ASPARTIC ACID | | 著者 | McGrath, A.P, Szewczyk, P, Chang, G. | | 登録日 | 2014-05-01 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
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4Q9K
 | | P-glycoprotein cocrystallised with QZ-Leu | | 分子名称: | (30F)L(30F)L(30F)L Peptide, Multidrug resistance protein 1A | | 著者 | McGrath, A.P, Szewczyk, P, Chang, G. | | 登録日 | 2014-05-01 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
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4Q9I
 | | P-glycoprotein cocrystallised with QZ-Ala | | 分子名称: | (30F)A(30F)A(30F)A Peptide, Multidrug resistance protein 1A | | 著者 | McGrath, A.P, Szewczyk, P, Chang, G. | | 登録日 | 2014-05-01 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (3.781 Å) | | 主引用文献 | Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
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4Q9L
 | | P-glycoprotein cocrystallised with QZ-Phe | | 分子名称: | (30F)F(30F)F(30F)F Peptide, Multidrug resistance protein 1A | | 著者 | McGrath, A.P, Szewczyk, P, Chang, G. | | 登録日 | 2014-05-01 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr.,Sect.D, 71, 2015
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6OCE
 | | Structure of the rice hyperosmolality-gated ion channel OSCA1.2 | | 分子名称: | stress-gated cation channel 1.2 | | 著者 | Maity, K, Heumann, J.M, McGrath, A.P, Chang, G, Stowell, M.H. | | 登録日 | 2019-03-23 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Cryo-EM structure of OSCA1.2 fromOryza sativaelucidates the mechanical basis of potential membrane hyperosmolality gating.
Proc.Natl.Acad.Sci.USA, 116, 2019
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