8ONT
 
 | | Structure of Setaria italica NRAT in complex with a nanobody | | 分子名称: | DIUNDECYL PHOSPHATIDYL CHOLINE, NRAMP related aluminium transporter, Nanobody1 | | 著者 | Ramanadane, K, Liziczai, M, Markovic, D, Straub, M.S, Rosalen, G.T, Udovcic, A, Dutzler, R, Manatschal, C. | | 登録日 | 2023-04-03 | | 公開日 | 2023-04-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | | 主引用文献 | Structural and functional properties of a plant NRAMP-related aluminum transporter.
Elife, 12, 2023
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7QIA
 | | Structure of apo-EleNRMT in complex with two nanobodies at 3.5A | | 分子名称: | Divalent metal cation transporter, Nanobody 1, Nanobody 2 | | 著者 | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | 登録日 | 2021-12-14 | | 公開日 | 2021-12-29 | | 最終更新日 | 2022-02-02 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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7QIC
 | | Structure of magnesium-bound EleNRMT in complex with two nanobodies at 4.1A | | 分子名称: | Divalent metal cation transporter, MAGNESIUM ION, Nanobody 1, ... | | 著者 | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | 登録日 | 2021-12-14 | | 公開日 | 2021-12-29 | | 最終更新日 | 2022-02-02 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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7QJI
 | | X-Ray Structure of apo-EleNRMT in complex with two Nanobodies at 4.1A | | 分子名称: | Divalent metal cation transporter, Elen-Nanobody-complex | | 著者 | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | 登録日 | 2021-12-16 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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7QJJ
 | | X-Ray Structure of a Mn2+ soak of EleNRMT in complex with two Nanobodies at 4.6A | | 分子名称: | Divalent metal cation transporter, Elen-Nb1-Nb2, MANGANESE (II) ION | | 著者 | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | 登録日 | 2021-12-16 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (4.6 Å) | | 主引用文献 | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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8DEA
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8DG6
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8D95
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8DNN
 | | Crystal structure of neutralizing antibody 80 in complex with SARS-CoV-2 receptor binding domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 80 FAB HEAVY CHAIN, 80 FAB LIGHT CHAIN, ... | | 著者 | Muthuraman, K, Kucharska, I, Ivanochko, D, Julien, J.P. | | 登録日 | 2022-07-11 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo.
Sci Transl Med, 15, 2023
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1ZW8
 | | Solution structure of a ZAP1 zinc-responsive domain provides insights into metalloregulatory transcriptional repression in Saccharomyces cerevisiae | | 分子名称: | ZINC ION, Zinc-responsive transcriptional regulator ZAP1 | | 著者 | Wang, Z, Feng, L.S, Venkataraman, K, Matskevich, V.A, Parasuram, P, Laity, J.H. | | 登録日 | 2005-06-03 | | 公開日 | 2006-01-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a Zap1 zinc-responsive domain provides insights into metalloregulatory transcriptional repression in Saccharomyces cerevisiae.
J.Mol.Biol., 357, 2006
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8Y4Z
 | | Monomeric HERC5 HECT c-lobe structure in solution | | 分子名称: | E3 ISG15--protein ligase HERC5 | | 著者 | Dag, C, Lambert, M, Kahraman, K, Lohn, F, Lee, W, Gocenler, O, Guntert, P, Dotsch, V. | | 登録日 | 2024-01-31 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Monomeric HERC5 HECT c-lobe structure in solution
To Be Published
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4GC5
 | | Crystal structure of murine TFB1M | | 分子名称: | ACETATE ION, Dimethyladenosine transferase 1, mitochondrial | | 著者 | Guja, K.E, Yakubovskaya, E, Shi, H, Mejia, E, Hambardjieva, E, Venkataraman, K, Karzai, A.W, Garcia-Diaz, M. | | 登録日 | 2012-07-29 | | 公開日 | 2013-07-10 | | 最終更新日 | 2013-10-02 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Structural basis for S-adenosylmethionine binding and methyltransferase activity by mitochondrial transcription factor B1.
Nucleic Acids Res., 41, 2013
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4GC9
 | | Crystal structure of murine TFB1M in complex with SAM | | 分子名称: | ACETATE ION, Dimethyladenosine transferase 1, mitochondrial, ... | | 著者 | Guja, K.E, Yakubovskaya, E, Shi, H, Mejia, E, Hambardjieva, E, Venkataraman, K, Karzai, A.W, Garcia-Diaz, M. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | | 主引用文献 | Structural basis for S-adenosylmethionine binding and methyltransferase activity by mitochondrial transcription factor B1.
Nucleic Acids Res., 41, 2013
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4ACP
 | | Deactivation of human IgG1 Fc by endoglycosidase treatment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG GAMMA-1 CHAIN C REGION | | 著者 | Raman, K, Bowden, T.A, Krishna, B.A, Dwek, R.A, Crispin, M, Scanlan, C.N. | | 登録日 | 2011-12-16 | | 公開日 | 2012-04-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Selective Deactivation of Serum Igg: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions.
J.Mol.Biol., 420, 2012
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2EC9
 | | Crystal structure analysis of human Factor VIIa , Souluble tissue factor complexed with BCX-3607 | | 分子名称: | 1,5-anhydro-D-glucitol, 2'-((5-CARBAMIMIDOYLPYRIDIN-2-YLAMINO)METHYL)-4-(ISOBUTYLCARBAMOYL)-4'-VINYLBIPHENYL-2-CARBOXYLIC ACID, CALCIUM ION, ... | | 著者 | Raman, K, Yarlagadda, B. | | 登録日 | 2007-02-13 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Probing the S2 site of factor VIIa to generate potent and selective inhibitors: the structure of BCX-3607 in complex with tissue factor-factor VIIa.
Acta Crystallogr.,Sect.D, 63, 2007
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3CBO
 | | SET7/9-ER-AdoHcy complex | | 分子名称: | BETA-MERCAPTOETHANOL, Estrogen receptor, GLYCEROL, ... | | 著者 | Cheng, X, Jia, D. | | 登録日 | 2008-02-22 | | 公開日 | 2008-05-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.
Mol.Cell, 30, 2008
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3CBM
 | | SET7/9-ER-AdoMet complex | | 分子名称: | BETA-MERCAPTOETHANOL, Estrogen receptor, Histone-lysine N-methyltransferase SETD7, ... | | 著者 | Cheng, X, Jia, D. | | 登録日 | 2008-02-22 | | 公開日 | 2008-05-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.
Mol.Cell, 30, 2008
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3CBP
 | | Set7/9-ER-Sinefungin complex | | 分子名称: | BETA-MERCAPTOETHANOL, Estrogen receptor, GLYCEROL, ... | | 著者 | Cheng, X, Jia, D. | | 登録日 | 2008-02-22 | | 公開日 | 2008-05-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase.
Mol.Cell, 30, 2008
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7N7X
 | | Crystal structure of BCX7353(ORLADEYO) in complex with human plasma kallikrein serine protease domain at 2.1 angstrom resolution | | 分子名称: | Orladeyo, PHOSPHATE ION, Plasma kallikrein light chain | | 著者 | Krishnan, R, Yarlagadda, B.S, Kotian, P, Polach, K.J, Zhang, W. | | 登録日 | 2021-06-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | | 主引用文献 | Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE).
J.Med.Chem., 64, 2021
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4TTH
 | | Crystal structure of a CDK6/Vcyclin complex with inhibitor bound | | 分子名称: | 9-cyclopentyl-N-(5-piperazin-1-ylpyridin-2-yl)pyrido[4,5]pyrrolo[1,2-d]pyrimidin-2-amine, Cyclin homolog, Cyclin-dependent kinase 6 | | 著者 | Piper, D.E, Walker, N, Wang, Z. | | 登録日 | 2014-06-20 | | 公開日 | 2014-08-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3.
J.Med.Chem., 57, 2014
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7K9Z
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with the Fab fragments of neutralizing antibodies 298 and 52 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 298 Fab Heavy Chain, 298 Fab Light Chain, ... | | 著者 | Newton, J.C, Kucharska, I, Rujas, E, Cui, H, Julien, J.P. | | 登録日 | 2020-09-29 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers.
Nat Commun, 12, 2021
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5C2C
 | | GWS1B RubisCO: Form II RubisCO derived from uncultivated Gallionellacea species (unliganded form) | | 分子名称: | CHLORIDE ION, Form II RubisCO, MAGNESIUM ION | | 著者 | Arbing, M.A, Varaljay, V.A, Satagopan, S, Tabita, F.R. | | 登録日 | 2015-06-15 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Functional metagenomic selection of ribulose 1, 5-bisphosphate carboxylase/oxygenase from uncultivated bacteria.
Environ.Microbiol., 18, 2016
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7L3N
 | | SARS-CoV 2 Spike Protein bound to LY-CoV555 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LY-CoV555 Fab heavy chain, ... | | 著者 | Goldsmith, J.A, McLellan, J.S. | | 登録日 | 2020-12-18 | | 公開日 | 2021-02-03 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection.
Biorxiv, 2020
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7KMG
 | | LY-CoV555 neutralizing antibody against SARS-CoV-2 | | 分子名称: | GLYCEROL, LY-CoV555 Fab heavy chain, LY-CoV555 Fab light chain, ... | | 著者 | Hendle, J, Pustilnik, A, Sauder, J.M, Coleman, K.A, Boyles, J.S, Dickinson, C.D. | | 登録日 | 2020-11-02 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates.
Sci Transl Med, 13, 2021
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7KMH
 | | LY-CoV488 neutralizing antibody against SARS-CoV-2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, LY-CoV488 Fab heavy chain, ... | | 著者 | Hendle, J, Pustilnik, A, Sauder, J.M, Boyles, J.S, Dickinson, C.D, Coleman, K.A. | | 登録日 | 2020-11-02 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates.
Sci Transl Med, 13, 2021
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