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2X7L
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BU of 2x7l by Molmil
Implications of the HIV-1 Rev dimer structure at 3.2A resolution for multimeric binding to the Rev response element
分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN, PROTEIN REV
著者DiMattia, M.A, Watts, N.R, Stahl, S.J, Rader, C, Wingfield, P.T, Stuart, D.I, Steven, A.C, Grimes, J.M.
登録日2010-03-01
公開日2010-03-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Implications of the HIV-1 Rev Dimer Structure at 3. 2 A Resolution for Multimeric Binding to the Rev Response Element.
Proc.Natl.Acad.Sci.USA, 107, 2010
7TUS
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BU of 7tus by Molmil
Sculpting a uniquely reactive cysteine residue for site-specific antibody conjugation
分子名称: Antibody Heavy Chain, Antibody Light Chain, DI(HYDROXYETHYL)ETHER, ...
著者Park, H, Rader, C.
登録日2022-02-03
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation.
Bioconjug.Chem., 33, 2022
6U85
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BU of 6u85 by Molmil
Site-specific lysine arylation as an alternative bioconjugation strategy for chemically programmed antibodies and antibody-drug conjugates
分子名称: Antibody Fab heavy chain, GLYCEROL, antibody Fab Light chain
著者Park, H, Rader, C.
登録日2019-09-04
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates.
Bioconjug.Chem., 30, 2019
6BA5
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BU of 6ba5 by Molmil
Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1
分子名称: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain Heavy chain, antibody R11, ...
著者Park, H, Rader, C.
登録日2017-10-12
公開日2018-06-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BAN
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BU of 6ban by Molmil
Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1
分子名称: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain R11 Heavy chain, Variable domain of R11 Light Chain
著者Park, H, Rader, C.
登録日2017-10-14
公開日2018-06-13
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6OSV
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BU of 6osv by Molmil
Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2
分子名称: Antibody heavy chain variable region, Antibody light chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2
著者Park, H, Rader, C.
登録日2019-05-02
公開日2020-04-01
最終更新日2020-05-13
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications.
J.Biol.Chem., 295, 2020
6OSN
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BU of 6osn by Molmil
Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2
分子名称: ACETATE ION, Tyrosine-protein kinase transmembrane receptor ROR2
著者Park, H, Rader, C.
登録日2019-05-01
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.083 Å)
主引用文献Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications.
J.Biol.Chem., 295, 2020
6OSH
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BU of 6osh by Molmil
Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2
分子名称: Antibody Light chain variable region, Antibody heavy chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2
著者Park, H, Rader, C.
登録日2019-05-01
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.117 Å)
主引用文献Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications.
J.Biol.Chem., 295, 2020
6DZR
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BU of 6dzr by Molmil
Crystal structure of h38C2 K99R mutation
分子名称: CITRATE ANION, SULFATE ION, h38c2 heavy chain, ...
著者Park, H, Rader, C.
登録日2018-07-05
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues.
Cell Chem Biol, 26, 2019
2PYP
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BU of 2pyp by Molmil
PHOTOACTIVE YELLOW PROTEIN, PHOTOSTATIONARY STATE, 50% GROUND STATE, 50% BLEACHED
分子名称: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
著者Genick, U.K, Borgstahl, G.E.O, Ng, K, Ren, Z, Pradervand, C, Burke, P, Srajer, V, Teng, T, Schildkamp, W, Mcree, D.E, Moffat, K, Getzoff, E.D.
登録日1997-02-03
公開日1998-04-29
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a protein photocycle intermediate by millisecond time-resolved crystallography.
Science, 275, 1997
2PYR
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BU of 2pyr by Molmil
PHOTOACTIVE YELLOW PROTEIN, 1 NANOSECOND INTERMEDIATE (287K)
分子名称: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN
著者Perman, B, Srajer, V, Ren, Z, Teng, T.Y, Pradervand, C, Ursby, T, Bourgeois, D, Schotte, F, Wulff, M, Kort, R, Hellingwerf, K, Moffat, K.
登録日1998-03-04
公開日1999-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Energy transduction on the nanosecond time scale: early structural events in a xanthopsin photocycle.
Science, 279, 1998
6CLX
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BU of 6clx by Molmil
Crystal structure of TnmH in complex with SAM
分子名称: O-methyltransferase, S-ADENOSYLMETHIONINE
著者Chang, C.Y, Annaval, T, Adhikari, A, Yan, X, Shen, B.
登録日2018-03-02
公開日2019-03-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Characterization of TnmH as anO-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody-Tiancimycin Conjugates.
J.Med.Chem., 63, 2020
6CLW
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BU of 6clw by Molmil
Crystal structure of TnmH
分子名称: O-methyltransferase
著者Chang, C.Y, Annaval, T, Adhikari, A, Yan, X, Shen, B.
登録日2018-03-02
公開日2019-03-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Characterization of TnmH as anO-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody-Tiancimycin Conjugates.
J.Med.Chem., 63, 2020
7BET
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BU of 7bet by Molmil
Structure of Ribonucleotide reductase R2 from Escherichia coli collected by femtosecond serial crystallography on a COC membrane
分子名称: FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta
著者Aurelius, O, John, J, Martiel, I, Marsh, M, Vera, L, Huang, C.Y, Olieric, V, Leonarski, P, Nass, K, Padeste, C, Karpik, A, Hogbom, M, Wang, M, Pedrini, B.
登録日2020-12-24
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Commissioning results from the SwissMX instrument for fixed target macromolecular crystallography at SwissFEL
To Be Published
7AT6
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BU of 7at6 by Molmil
Structure of thaumatin collected by femtosecond serial crystallography on a COC membrane
分子名称: L(+)-TARTARIC ACID, R-1,2-PROPANEDIOL, SODIUM ION, ...
著者Martiel, I, Marsh, M, Vera, L, Huang, C.Y, Olieric, V, Leonarski, P, Nass, K, Padeste, C, Karpik, A, Wang, M, Pedrini, B.
登録日2020-10-29
公開日2021-11-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Commissioning results from the SwissMX instrument for fixed target macromolecular crystallography at SwissFEL
To Be Published

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件を2024-08-28に公開中

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