5ZF2
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3O39
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6LQZ
| Solution structure of Taf14ET-Sth1EBMC | 分子名称: | Nuclear protein STH1/NPS1, Transcription initiation factor TFIID subunit 14 | 著者 | Wu, B, Chen, G, Chen, Y. | 登録日 | 2020-01-15 | 公開日 | 2020-08-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Taf14 recognizes a common motif in transcriptional machineries and facilitates their clustering by phase separation. Nat Commun, 11, 2020
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5ZUU
| Crystal structure of AtCPSF30 YTH domain in complex with 10mer m6A-modified RNA | 分子名称: | 30-kDa cleavage and polyadenylation specificity factor 30, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Wu, B, Nie, H, Li, S, Patel, D.J. | 登録日 | 2018-05-08 | 公開日 | 2019-05-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis. Mol Plant, 2021
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6BJF
| NMR Structural and biophysical functional analysis of intracellular loop 5 of the NHE1 isoform of the Na+/H+ exchanger. | 分子名称: | GLY-LEU-THR-TRP-PHE-ILE-ASN-LYS-PHE-ARG-ILE-VAL-LYS | 著者 | McKay, R, Wong, K, Towle, K, Fliegel, L. | 登録日 | 2017-11-06 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Diverse residues of intracellular loop 5 of the Na+/H+exchanger modulate proton sensing, expression, activity and targeting. Biochim Biophys Acta Biomembr, 1861, 2019
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5WO1
| Chaperone Spy H96L bound to Im7 L18A L19A L37A (Im7 un-modeled) | 分子名称: | CHLORIDE ION, GLUTAMIC ACID, IMIDAZOLE, ... | 著者 | Horowitz, S, Koldewey, P, Martin, R, Bardwell, J.C.A. | 登録日 | 2017-08-01 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Visualizing chaperone-assisted protein folding. Nat. Struct. Mol. Biol., 23, 2016
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5WO2
| Chaperone Spy bound to Casein Fragment (Casein un-modeled) | 分子名称: | CHLORIDE ION, IMIDAZOLE, Periplasmic chaperone Spy, ... | 著者 | Horowitz, S, Koldewey, P, Martin, R, Bardwell, J.C.A. | 登録日 | 2017-08-01 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.769 Å) | 主引用文献 | Visualizing chaperone-assisted protein folding. Nat. Struct. Mol. Biol., 23, 2016
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5WNW
| Chaperone Spy bound to Im7 6-45 ensemble | 分子名称: | CHLORIDE ION, Colicin-E7 immunity protein, IMIDAZOLE, ... | 著者 | Horowitz, S, Salmon, L, Koldewey, P, Ahlstrom, L.S, Martin, R, Xu, Q, Afonine, P.V, Trievel, R.C, Brooks, C.L, Bardwell, J.C.A. | 登録日 | 2017-08-01 | 公開日 | 2017-08-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Visualizing chaperone-assisted protein folding. Nat. Struct. Mol. Biol., 23, 2016
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5WO3
| Chaperone Spy bound to Im7 (Im7 un-modeled) | 分子名称: | CHLORIDE ION, IMIDAZOLE, Periplasmic chaperone Spy, ... | 著者 | Horowitz, S, Koldewey, P, Martin, R, Bardwell, J.C.A. | 登録日 | 2017-08-01 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Visualizing chaperone-assisted protein folding. Nat. Struct. Mol. Biol., 23, 2016
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5YWL
| SsCR_L211H | 分子名称: | Protein induced by osmotic stress | 著者 | Shang, Y.P, Chen, Q, Li, A.T, Yu, H.L, Xu, J.H. | 登録日 | 2017-11-29 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | 主引用文献 | Attenuated substrate inhibition of a haloketone reductase via structure-guided loop engineering. J.Biotechnol., 308, 2020
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5YWN
| SsCR_L211H-NADP+ | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Protein induced by osmotic stress | 著者 | Shang, Y.P, Chen, Q, Yu, H.L, Xu, J.H. | 登録日 | 2017-11-29 | 公開日 | 2019-03-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.039 Å) | 主引用文献 | Attenuated substrate inhibition of a haloketone reductase via structure-guided loop engineering. J.Biotechnol., 308, 2020
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5YW4
| Structure-Guided Engineering of Reductase: Efficient Attenuating Substrate Inhibition in Asymmetric Catalysis | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Protein induced by osmotic stress | 著者 | Shang, Y.P, Chen, Q, Li, A.T, Yu, H.L, Xu, J.H. | 登録日 | 2017-11-28 | 公開日 | 2019-03-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.047 Å) | 主引用文献 | Attenuated substrate inhibition of a haloketone reductase via structure-guided loop engineering. J.Biotechnol., 308, 2020
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7SVM
| DPP8 IN COMPLEX WITH LIGAND ICeD-2 | 分子名称: | (2S)-2-amino-1-(1,3-dihydro-2H-isoindol-2-yl)-2-[(1r,4S)-4-(pyrrolidin-1-yl)cyclohexyl]ethan-1-one, Dipeptidyl peptidase 8, trimethylamine oxide | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | 登録日 | 2021-11-19 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells. Acs Chem.Biol., 17, 2022
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7SVN
| DPP9 IN COMPLEX WITH LIGAND ICeD-1 | 分子名称: | (2S,4S)-1-[(2S)-2-amino-2-cyclohexylacetyl]-4-fluoropyrrolidine-2-carbonitrile, Dipeptidyl peptidase 9 | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | 登録日 | 2021-11-19 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells. Acs Chem.Biol., 17, 2022
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7SVO
| DPP8 IN COMPLEX WITH LIGAND ICeD-1 | 分子名称: | (2S,4S)-1-[(2S)-2-amino-2-cyclohexylacetyl]-4-fluoropyrrolidine-2-carbonitrile, Dipeptidyl peptidase 8, trimethylamine oxide | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | 登録日 | 2021-11-19 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells. Acs Chem.Biol., 17, 2022
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7SVL
| DPP9 IN COMPLEX WITH LIGAND ICeD-2 | 分子名称: | (2S)-2-amino-1-(1,3-dihydro-2H-isoindol-2-yl)-2-[(1r,4S)-4-(pyrrolidin-1-yl)cyclohexyl]ethan-1-one, Dipeptidyl peptidase 9 | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | 登録日 | 2021-11-19 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells. Acs Chem.Biol., 17, 2022
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8WVB
| Crystal structure of Lsd18 mutant S195M | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Putative epoxidase LasC | 著者 | Liu, N, Xiao, H.L, Chen, X. | 登録日 | 2023-10-23 | 公開日 | 2023-12-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Simultaneous Improvement in the Thermostability and Catalytic Activity of Epoxidase Lsd18 for the Synthesis of Lasalocid A. Int J Mol Sci, 24, 2023
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8WVF
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7W6L
| The crystal structure of MLL3-RBBP5-ASH2L in complex with H3K4me0 peptide | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, ... | 著者 | Zhao, L, Li, Y, Chen, Y. | 登録日 | 2021-12-01 | 公開日 | 2022-09-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases. Mol.Cell, 82, 2022
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7W6A
| Crystal structure of the MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L complex | 分子名称: | Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Zhao, L, Li, Y, Chen, Y. | 登録日 | 2021-12-01 | 公開日 | 2022-09-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases. Mol.Cell, 82, 2022
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7W6I
| The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me1 peptide | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | 著者 | Zhao, L, Li, Y, Chen, Y. | 登録日 | 2021-12-01 | 公開日 | 2022-09-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases. Mol.Cell, 82, 2022
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7W67
| The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me0 peptide | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | 著者 | Zhao, L, Li, Y, Chen, Y. | 登録日 | 2021-12-01 | 公開日 | 2022-09-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases. Mol.Cell, 82, 2022
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7W6J
| The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me2 peptide | 分子名称: | Histone H3.3C, Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, ... | 著者 | Zhao, L, Li, Y, Chen, Y. | 登録日 | 2021-12-01 | 公開日 | 2022-09-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Structural basis for product specificities of MLL family methyltransferases. Mol.Cell, 82, 2022
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6AGH
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6AGJ
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