2IXF
 
 | | Crystal structure of the ATPase domain of TAP1 with ATP (D645Q, Q678H mutant) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ANTIGEN PEPTIDE TRANSPORTER 1, GLYCEROL, ... | | 著者 | Procko, E, Ferrin-O'Connell, I, Ng, S.-L, Gaudet, R. | | 登録日 | 2006-07-08 | | 公開日 | 2006-10-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric Abc Transporter.
Mol.Cell, 24, 2001
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2IXE
 | | Crystal structure of the ATPase domain of TAP1 with ATP (D645N mutant) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ANTIGEN PEPTIDE TRANSPORTER 1, MAGNESIUM ION, ... | | 著者 | Procko, E, Ferrin-O'Connell, I, Ng, S.-L, Gaudet, R. | | 登録日 | 2006-07-07 | | 公開日 | 2006-10-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric Abc Transporter.
Mol.Cell, 24, 2001
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2IXG
 | | Crystal structure of the ATPase domain of TAP1 with ATP (S621A, G622V, D645N mutant) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ANTIGEN PEPTIDE TRANSPORTER 1, GLYCEROL | | 著者 | Procko, E, Ferrin-O'Connell, I, Ng, S.-L, Gaudet, R. | | 登録日 | 2006-07-08 | | 公開日 | 2006-10-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric Abc Transporter.
Mol.Cell, 24, 2001
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4OYD
 | | Crystal structure of a computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein | | 分子名称: | 1,2-ETHANEDIOL, Apoptosis regulator BHRF1, Computationally designed Inhibitor | | 著者 | Shen, B, Procko, E, Baker, D, Stoddard, B. | | 登録日 | 2014-02-11 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A computationally designed inhibitor of an epstein-barr viral bcl-2 protein induces apoptosis in infected cells.
Cell, 157, 2014
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3VB8
 | | Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR43 | | 分子名称: | Engineered protein, SULFATE ION | | 著者 | Seetharaman, J, Su, M, Procko, E, Baker, D, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-12-31 | | 公開日 | 2012-06-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Computational design of a protein-based enzyme inhibitor.
J.Mol.Biol., 425, 2013
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5JSN
 | | Bcl2-inhibitor complex | | 分子名称: | Apoptosis regulator Bcl-2, Bcl2 inhibitor | | 著者 | Shen, B.W, Stoddard, B.L. | | 登録日 | 2016-05-09 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.
Elife, 5, 2016
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6NPR
 | | Crystal structure of H-2Dd with C84-C139 disulfide in complex with gp120 derived peptide P18-I10 | | 分子名称: | ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | | 著者 | Toor, J, McShan, A.C, Tripathi, S.M, Sgourakis, N.G. | | 登録日 | 2019-01-18 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5JSB
 | | Crystal structure of Mcl1-inhibitor complex | | 分子名称: | Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1 inhibitor | | 著者 | Shen, B.W, Stoddard, B.L. | | 登録日 | 2016-05-07 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.
Elife, 5, 2016
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7RNO
 | | Model of the Ac-6-FP/hpMR1/bB2m/TAPBPR complex from integrated docking, NMR and restrained MD | | 分子名称: | Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, N-(6-formyl-4-oxo-3,4-dihydropteridin-2-yl)acetamide, ... | | 著者 | McShan, A.C, Sgourakis, N.G. | | 登録日 | 2021-07-29 | | 公開日 | 2022-05-11 | | 最終更新日 | 2022-08-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules.
Nat.Chem.Biol., 18, 2022
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5E9D
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4J3O
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3SUI
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4DX2
 | | Crystal structure of the human TRPV4 ankyrin repeat domain | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Transient receptor potential cation channel subfamily V member 4, ... | | 著者 | Inada, H, Gaudet, R. | | 登録日 | 2012-02-27 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel.
Biochemistry, 51, 2012
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4DX1
 | | Crystal structure of the human TRPV4 ankyrin repeat domain | | 分子名称: | GLYCEROL, PHOSPHATE ION, Transient receptor potential cation channel subfamily V member 4 | | 著者 | Inada, H, Gaudet, R. | | 登録日 | 2012-02-27 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel.
Biochemistry, 51, 2012
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2NYJ
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2PNN
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