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1YS5
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BU of 1ys5 by Molmil
Solution structure of the antigenic domain of GNA1870 of Neisseria meningitidis
分子名称: lipoprotein
著者Cantini, F, Savino, S, Masignani, V, Pizza, M, Scarselli, M, Swennen, E, Romagnoli, G, Veggi, D, Banci, L, Rappuoli, R.
登録日2005-02-07
公開日2006-02-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis
J.Biol.Chem., 281, 2006
4E9L
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BU of 4e9l by Molmil
FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections
分子名称: Attaching and effacing protein, pathogenesis factor
著者Spraggon, G, Nesta, B, Alteri, C, Gomes Moriel, D, Rosini, R, Veggi, D, Smith, S, Bertoldi, I, Pastorello, I, Ferlenghi, I, Fontana, M.R, Frankel, G, Mobley, H.L.T, Rappuoli, R, Pizza, M, Serino, L, Soriana, M.
登録日2012-03-21
公開日2012-04-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections.
MBio, 3, 2012
2KXI
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BU of 2kxi by Molmil
Solution NMR structure of the apoform of NarE (NMB1343)
分子名称: Uncharacterized protein
著者Koehler, C, Carlier, L, Veggi, D, Soriani, M, Pizza, M, Boelens, R, Bonvin, A.M.J.J.
登録日2010-05-06
公開日2011-03-02
最終更新日2018-08-08
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the apoform of NarE (NMB1343)
To be Published
2KC0
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BU of 2kc0 by Molmil
Solution structure of the factor H binding protein
分子名称: lipoprotein
著者Cantini, F, Veggi, D, Dragonetti, S, Savino, S, Scarselli, M, Romagnoli, G, Pizza, M, Banci, L, Rappuoli, R.
登録日2008-12-13
公開日2009-02-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidis
J.Biol.Chem., 284, 2009
2LFU
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BU of 2lfu by Molmil
The structure of a N. meningitides protein targeted for vaccine development
分子名称: Gna2132
著者Esposito, V, Musi, V, De Chiara, C, Kelly, G, Veggi, D, Pizza, M, Pastore, A.
登録日2011-07-15
公開日2011-10-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the C-terminal Domain of Neisseria Heparin Binding Antigen (NHBA), One of the Main Antigens of a Novel Vaccine against Neisseria meningitidis.
J.Biol.Chem., 286, 2011
1HTL
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BU of 1htl by Molmil
MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
分子名称: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B
著者Merritt, E.A, Hol, W.G.J.
登録日1995-02-15
公開日1995-04-20
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli.
Nat.Struct.Biol., 2, 1995
1LTG
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BU of 1ltg by Molmil
THE ARG7LYS MUTANT OF HEAT-LABILE ENTEROTOXIN EXHIBITS GREAT FLEXIBILITY OF ACTIVE SITE LOOP 47-56 OF THE A SUBUNIT
分子名称: HEAT-LABILE ENTEROTOXIN
著者Van Den Akker, F, Hol, W.G.J.
登録日1995-06-13
公開日1995-09-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
Biochemistry, 34, 1995
1LT4
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BU of 1lt4 by Molmil
HEAT-LABILE ENTEROTOXIN MUTANT S63K
分子名称: HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Van Den Akker, F, Hol, W.G.J.
登録日1997-04-14
公開日1997-06-16
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
Protein Sci., 6, 1997
4CJD
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BU of 4cjd by Molmil
Crystal structure of Neisseria meningitidis trimeric autotransporter and vaccine antigen NadA
分子名称: IODIDE ION, NADA
著者Malito, E, Biancucci, M, Spraggon, G, Bottomley, M.J.
登録日2013-12-19
公開日2014-11-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.056 Å)
主引用文献Structure of the Meningococcal Vaccine Antigen Nada and Epitope Mapping of a Bactericidal Antibody.
Proc.Natl.Acad.Sci.USA, 111, 2014
7NRU
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BU of 7nru by Molmil
Structure of a natural chimera of meningococcal factor H binding protein belonging to NL096 strain
分子名称: Factor H binding protein variant 1-2,3.x, SULFATE ION
著者Veggi, D, Malito, E, Bottomley, M.J.
登録日2021-03-04
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.21998358 Å)
主引用文献Structural characterization of a cross-protective natural chimera of factor H binding protein from meningococcal serogroup B strain NL096.
Comput Struct Biotechnol J, 20, 2022
6XZW
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BU of 6xzw by Molmil
Crystal structure of the meningococcal vaccine antigen fHbp in complex with a cross-reactive human Fab.
分子名称: 1,2-ETHANEDIOL, Fab 4B3 (heavy chain), Fab 4B3 (light chain), ...
著者Veggi, D, Cozzi, R.
登録日2020-02-05
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp.
Plos Pathog., 16, 2020
2Y7S
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BU of 2y7s by Molmil
Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity
分子名称: FACTOR H BINDING PROTEIN
著者Malito, E, Spraggon, G, Bottomley, M.J.
登録日2011-02-01
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity.
Sci.Transl.Med, 3, 2011
5UR8
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BU of 5ur8 by Molmil
Human antibody fragment (Fab) to meningococcal Factor H binding protein
分子名称: human immunoglobulin gamma, heavy chain Fd fragment, kappa light chain
著者Beernink, P.T.
登録日2017-02-09
公開日2018-02-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75500226 Å)
主引用文献Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp.
Nat Commun, 9, 2018
2YPV
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BU of 2ypv by Molmil
Crystal structure of the Meningococcal vaccine antigen factor H binding protein in complex with a bactericidal antibody
分子名称: 1,2-ETHANEDIOL, FAB 12C1, LIPOPROTEIN
著者Malito, E, Veggi, D, Bottomley, M.J.
登録日2012-11-01
公開日2013-02-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Defining a Protective Epitope on Factor H Binding Protein, a Key Meningococcal Virulence Factor and Vaccine Antigen.
Proc.Natl.Acad.Sci.USA, 110, 2013
5O14
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BU of 5o14 by Molmil
Co-crystal structure of a cross-reactive bactericidal human antibody targeting meningococcal vaccine antigen factor H binding protein
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Fab 1A12 Heavy Chain, ...
著者Lopez-Sagaseta, J.
登録日2017-05-18
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.195 Å)
主引用文献Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp.
Nat Commun, 9, 2018
6EUN
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BU of 6eun by Molmil
Crystal structure of Neisseria meningitidis vaccine antigen NadA variant 3
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, ...
著者Dello Iacono, L, Liguori, A, Malito, E, Bottomley, M.J.
登録日2017-10-30
公開日2018-10-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies.
MBio, 9, 2018
6EUP
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BU of 6eup by Molmil
Crystal structure of Neisseria meningitidis NadA variant 3 double mutant A33I-I38L
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Adhesin A, ...
著者Dello Iacono, L, Liguori, A, Malito, E, Bottomley, M.J.
登録日2017-10-31
公開日2018-10-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies.
MBio, 9, 2018
5AIQ
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BU of 5aiq by Molmil
Crystal structure of ligand-free NadR
分子名称: TRANSCRIPTIONAL REGULATOR, MARR FAMILY
著者Liguori, A, Malito, E, Bottomley, M.J.
登録日2015-02-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.716 Å)
主引用文献Molecular Basis of Ligand-Dependent Regulation of Nadr, the Transcriptional Repressor of Meningococcal Virulence Factor Nada.
Plos Pathog., 12, 2016
5AIP
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BU of 5aip by Molmil
Crystal structure of NadR in complex with 4-hydroxyphenylacetate
分子名称: 4-HYDROXYPHENYLACETATE, TRANSCRIPTIONAL REGULATOR, MARR FAMILY
著者Liguori, A, Malito, E, Bottomley, M.J.
登録日2015-02-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Basis of Ligand-Dependent Regulation of Nadr, the Transcriptional Repressor of Meningococcal Virulence Factor Nada.
Plos Pathog., 12, 2016
7B62
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BU of 7b62 by Molmil
Crystal structure of SARS-CoV-2 spike protein N-terminal domain in complex with biliverdin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, DI(HYDROXYETHYL)ETHER, ...
著者Pye, V.E, Rosa, A, Roustan, C, Cherepanov, P.
登録日2020-12-07
公開日2021-04-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.
Sci Adv, 7, 2021
7NT9
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BU of 7nt9 by Molmil
Trimeric SARS-CoV-2 spike ectodomain in complex with biliverdin (closed conformation)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ...
著者Rosa, A, Pye, V.E, Nans, A, Cherepanov, P.
登録日2021-03-09
公開日2021-04-28
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.
Sci Adv, 7, 2021
7NTA
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BU of 7nta by Molmil
Trimeric SARS-CoV-2 spike ectodomain in complex with biliverdin (one RBD erect)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ...
著者Rosa, A, Pye, V.E, Nans, A, Cherepanov, P.
登録日2021-03-09
公開日2021-04-28
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.
Sci Adv, 7, 2021
7NTC
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BU of 7ntc by Molmil
Trimeric SARS-CoV-2 spike ectodomain bound to P008_056 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ...
著者Rosa, A, Pye, V.E, Nans, A, Cherepanov, P.
登録日2021-03-09
公開日2021-04-28
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.
Sci Adv, 7, 2021
6SP2
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BU of 6sp2 by Molmil
CryoEM structure of SERINC from Drosophila melanogaster
分子名称: CARDIOLIPIN, Lauryl Maltose Neopentyl Glycol, Membrane protein TMS1d, ...
著者Pye, V.E, Nans, A, Cherepanov, P.
登録日2019-08-30
公開日2020-01-01
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献A bipartite structural organization defines the SERINC family of HIV-1 restriction factors.
Nat.Struct.Mol.Biol., 27, 2020

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