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6UC5
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Fab397 in complex with NPNA peptide
分子名称: Fab397 heavy chain, Fab397 light chain, NPNA peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2019-09-13
公開日2020-01-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite Protein.
J.Mol.Biol., 432, 2020
6W05
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BU of 6w05 by Molmil
Crystal structure of Fab356 in complex with NPNA2 peptide from circumsporozoite protein
分子名称: Fab356 heavy chain, Fab356 light chain, NPNA2 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-02-29
公開日2020-07-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.516 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6W00
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Crystal structure of Fab239 in complex with NPNA2 peptide from circumsporozoite protein
分子名称: Fab239 heavy chain, Fab239 light chain, Immunoglobulin G-binding protein G, ...
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-02-28
公開日2020-07-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.853 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6WG1
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Crystal structure of Fab399 in complex with NPNA6 peptide from circumsporozoite protein
分子名称: Fab399 heavy chain, Fab399 light chain, NPNA6 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.086 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6WFZ
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Crystal structure of Fab399 in complex with NPNA3 peptide from circumsporozoite protein
分子名称: Fab399 heavy chain, Fab399 light chain, NPNA3 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6WFY
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Crystal structure of Fab224 in complex with NPNA4 peptide from circumsporozoite protein
分子名称: Fab224 heavy chain, Fab224 light chain, NPNA4 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.226 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6WG0
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Crystal structure of Fab366 in complex with NPNA3 peptide from circumsporozoite protein
分子名称: Fab366 heavy chain, Fab366 light chain, NPNA3 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6WFW
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Crystal structure of Fab364 in complex with NPNA2 peptide from circumsporozoite protein
分子名称: Fab364 heavy chain, Fab364 light chain, Immunoglobulin G-binding protein G, ...
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6WG2
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Crystal structure of Fab239 in complex with NPNA4 peptide from circumsporozoite protein
分子名称: Fab239 heavy chain, Fab239 light chain, NPNA4 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.534 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
6WFX
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Crystal structure of Fab395 in complex with NPNA2 peptide from circumsporozoite protein
分子名称: Fab395 heavy chain, Fab395 light chain, NPNA2 peptide
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun, 12, 2021
8TFQ
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Fab from C10-S66K antibody in complex with fentanyl
分子名称: Heavy chain from Fab of C10_S66K antibody, Light chain from Fab of C10_S66K antibody, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
著者Pholcharee, T, Wilson, I.A.
登録日2023-07-11
公開日2023-08-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
Acs Chem Neurosci, 14, 2023
8TFP
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Fab from C10-S66K antibody in complex with carfentanil
分子名称: Carfentanil, Heavy chain of Fab from C10-S66K antibody, Light chain of Fab from C10-S66K antibody
著者Pholcharee, T, Wilson, I.A.
登録日2023-07-11
公開日2023-08-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
Acs Chem Neurosci, 14, 2023
8TFR
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Apo Fab from C10-S66K antibody
分子名称: Heavy chain from Fab of C10_S66K antibody, Immunoglobulin G-binding protein G, Light chain from Fab of C10_S66K antibody
著者Pholcharee, T, Wilson, I.A.
登録日2023-07-11
公開日2023-08-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
Acs Chem Neurosci, 14, 2023
7K76
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BU of 7k76 by Molmil
Crystal structure of MAD2-6 IgG Fab in complex with PfCSP N-terminal peptide.
分子名称: Heavy chain of MAD2-6 IgG Fab, Light chain of MAD2-6 IgG Fab, PfCSP N-terminal peptide P17
著者Pholcharee, T, Wilson, I.A.
登録日2020-09-22
公開日2021-06-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Functional human IgA targets a conserved site on malaria sporozoites.
Sci Transl Med, 13, 2021
7K75
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Crystal structure of MAD2-6 IgA Fab in complex with PfCSP N-terminal peptide.
分子名称: Heavy chain of MAD2-6 IgA Fab, Light chain of MAD2-6 IgA Fab, PfCSP N-terminal peptide P17
著者Pholcharee, T, Wilson, I.A.
登録日2020-09-22
公開日2021-06-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Functional human IgA targets a conserved site on malaria sporozoites.
Sci Transl Med, 13, 2021
7RXJ
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Fab236 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab236 heavy chain, Fab236 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.345 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7S0X
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Fab352 in complex with the C-terminal alphaTSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab352 heavy chain, Fab352 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-31
公開日2022-03-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXI
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Fab234 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab234 heavy chain, Fab234 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXP
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Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.761 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXL
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Fab1488 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab1488 heavy chain, Fab1488 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.823 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
8A44
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Plasmodium vivax Duffy binding protein region II bound the DARC ectodomain and monoclonal antibody DB1
分子名称: Atypical chemokine receptor 1, Duffy binding protein, Heavy chain of monoclonal antibody DB1, ...
著者Moskovitz, R, Higgins, M.K.
登録日2022-06-10
公開日2023-06-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural basis for DARC binding in reticulocyte invasion by Plasmodium vivax.
Nat Commun, 14, 2023
6PBW
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Crystal structure of Fab667 complex
分子名称: Fab667 heavy chain, Fab667 light chain, GLYCEROL, ...
著者Oyen, D, Wilson, I.A.
登録日2019-06-14
公開日2020-03-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.058 Å)
主引用文献Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
6PBV
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Crystal structure of Fab668 complex
分子名称: 1,2-ETHANEDIOL, Fab668 heavy chain, Fab668 light chain, ...
著者Oyen, D, Wilson, I.A.
登録日2019-06-14
公開日2020-03-04
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.566 Å)
主引用文献Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
6UUD
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Crystal structure of antibody 5D5 in complex with PfCSP N-terminal peptide
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 5D5 Antibody Fab, ...
著者Thai, E, Scally, S.W, Julien, J.P.
登録日2019-10-30
公開日2020-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity.
J.Exp.Med., 217, 2020
8DYT
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Cryo-EM structure of 227 Fab in complex with (NPNA)8 peptide
分子名称: 227 Fab heavy chain, 227 Fab light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023

 

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件を2024-11-06に公開中

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