8QUL
| Hexameric HIV-1 CA in complex with DDD00100555 | 分子名称: | 3-(BENZYLOXY)PYRIDIN-2-AMINE, Spacer peptide 1 | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-16 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QUY
| Hexameric HIV-1 CA in complex with DDD01728501 | 分子名称: | 1,2-ETHANEDIOL, 4-[(4-methylphenyl)methyl]-1~{H}-quinoxaline-2,3-dione, Spacer peptide 1 | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-17 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QUI
| Hexameric HIV-1 CA in complex with DDD00024969 | 分子名称: | Spacer peptide 1, ethyl (3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetate | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-16 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QUW
| Hexameric HIV-1 CA in complex with DDD01044153 | 分子名称: | (4~{R})-7-oxidanyl-4-phenyl-3,4-dihydro-1~{H}-quinolin-2-one, 1,2-ETHANEDIOL, Spacer peptide 1 | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-17 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QVA
| Hexameric HIV-1 CA in complex with DDD01829894 | 分子名称: | 1,2-ETHANEDIOL, 7-azanyl-3-(phenylmethyl)-1~{H}-benzimidazol-2-one, Spacer peptide 1 | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-17 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QV9
| Hexameric HIV-1 CA in complex with DDD01829021 | 分子名称: | 1,2-ETHANEDIOL, 7-bromanyl-3-(phenylmethyl)-1~{H}-benzimidazol-2-one, Spacer peptide 1 | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-17 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QUB
| Hexameric HIV-1 CA in complex with DDD00074110 | 分子名称: | (1~{S})-1-phenyl-2,4-dihydro-1~{H}-isoquinolin-3-one, Spacer peptide 1 | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-16 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QUJ
| Hexameric HIV-1 CA in complex with DDD00100452 | 分子名称: | 1,2-ETHANEDIOL, 3-(phenylmethyl)-1~{H}-imidazol-2-one, Spacer peptide 1 | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-16 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QV4
| Hexameric HIV-1 CA in complex with DDD01728503 | 分子名称: | 1,2-ETHANEDIOL, Spacer peptide 1, ethyl 2-(3-oxidanylidene-2,4-dihydroquinoxalin-1-yl)ethanoate | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-17 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QUH
| Hexameric HIV-1 CA in complex with DDD00057456 | 分子名称: | 4-methylquinolin-2-ol, Spacer peptide 1 | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-16 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QUK
| Hexameric HIV-1 CA in complex with DDD00100439 | 分子名称: | (phenylmethyl) 3-oxidanylidenepiperazine-1-carboxylate, 1,2-ETHANEDIOL, Spacer peptide 1 | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-16 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QUX
| Hexameric HIV-1 CA in complex with DDD00100333 | 分子名称: | 1,2-ETHANEDIOL, 4-benzyl-3,4-dihydroquinoxalin-2(1H)-one, Spacer peptide 1 | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-17 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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8QV1
| Hexameric HIV-1 CA in complex with DDD01728505 | 分子名称: | Spacer peptide 1, methyl 2-(2-oxidanylidene-1~{H}-quinolin-4-yl)ethanoate | 著者 | Petit, A.P, Fyfe, P.K. | 登録日 | 2023-10-17 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments. Chemmedchem, 2024
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4XH9
| CRYSTAL STRUCTURE OF HUMAN RHOA IN COMPLEX WITH DH/PH FRAGMENT OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR NET1 | 分子名称: | Neuroepithelial cell-transforming gene 1 protein, Transforming protein RhoA | 著者 | Garcia, C, Petit, P, Boutin, J.A, Ferry, G, Vuillard, L. | 登録日 | 2015-01-05 | 公開日 | 2015-01-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A structural study of the complex between neuroepithelial cell transforming gene 1 (Net1) and RhoA reveals a potential anticancer drug hot spot. J. Biol. Chem., 293, 2018
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4GMJ
| Structure of human NOT1 MIF4G domain co-crystallized with CAF1 | 分子名称: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ... | 著者 | Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E. | 登録日 | 2012-08-16 | 公開日 | 2012-10-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex Nucleic Acids Res., 40, 2012
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4GML
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5E8J
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5E9J
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5E9W
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8SDC
| Crystal structure of fluoroacetate dehalogenase Daro3835 apoenzyme | 分子名称: | Alpha/beta hydrolase fold protein, CHLORIDE ION | 著者 | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | 登録日 | 2023-04-06 | 公開日 | 2023-09-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases. Febs J., 290, 2023
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8SDD
| Crystal structure of fluoroacetate dehalogenase Daro3835 H274N mutant with D107-glycolyl intermediate | 分子名称: | Alpha/beta hydrolase fold protein | 著者 | Stogios, P.J, Skarina, T, Khusnutdinova, A, Iakounine, A, Savchenko, A. | 登録日 | 2023-04-06 | 公開日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases. Febs J., 290, 2023
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