8QUW

Hexameric HIV-1 CA in complex with DDD01044153

Summary for 8QUW

Entry DOI	10.2210/pdb8quw/pdb
Related	5HGM 8QUB 8QUH 8QUI 8QUJ 8QUK 8QUL
Descriptor	Spacer peptide 1, (4~{R})-7-oxidanyl-4-phenyl-3,4-dihydro-1~{H}-quinolin-2-one, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	capsid, viral protein
Biological source	Human immunodeficiency virus 1
Total number of polymer chains	1
Total formula weight	25762.61
Authors	Petit, A.P.,Fyfe, P.K. (deposition date: 2023-10-17, release date: 2024-03-27, Last modification date: 2024-07-10)
Primary citation	Lang, S.,Fletcher, D.A.,Petit, A.P.,Luise, N.,Fyfe, P.,Zuccotto, F.,Porter, D.,Hope, A.,Bellany, F.,Kerr, C.,Mackenzie, C.J.,Wyatt, P.G.,Gray, D.W. Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV-CA Binding Fragments. Chemmedchem, 19:e202400025-e202400025, 2024 Cited by PubMed: 38581280 DOI: 10.1002/cmdc.202400025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.02 Å)

Structure validation