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2L8C
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NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)2 Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1 - UU pair with zero hydrogen bond pairs
分子名称: RNA (5'-R(*CP*CP*GP*CP*UP*GP*CP*GP*G)-3')
著者Parkesh, R, Fountain, M.A, Disney, M.D.
登録日2011-01-07
公開日2011-02-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)(2) Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1.
Biochemistry, 50, 2011
2L8W
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r(CCGCUGCGG)2 UU Internal Loop Found in Myotonic Dystrophy Type 1 - UU pair with two hydrogen bond pairs
分子名称: RNA (5'-R(*CP*CP*GP*CP*UP*GP*CP*GP*G)-3')
著者Parkesh, R, Fountain, M, Disney, M.
登録日2011-01-26
公開日2011-02-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)(2) Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1.
Biochemistry, 50, 2011
2L8U
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NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)2 Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1 - UU pair with one hydrogen bond pair
分子名称: RNA (5'-R(*CP*CP*GP*CP*UP*GP*CP*GP*G)-3')
著者Parkesh, R, Fountain, M.A, Disney, M.D.
登録日2011-01-25
公開日2011-02-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Spectroscopy and Molecular Dynamics Simulation of r(CCGCUGCGG)(2) Reveal a Dynamic UU Internal Loop Found in Myotonic Dystrophy Type 1.
Biochemistry, 50, 2011
3SZX
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Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
分子名称: RNA (5'-R(P*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3')
著者Kumar, A, Park, H, Pengfei, F, Parkesh, R, Guo, M, Nettles, K.W, Disney, M.D.
登録日2011-07-19
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
3SYW
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Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
分子名称: PHOSPHATE ION, RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3')
著者Kumar, A, Park, H, Pengfei, F, Parkesh, R, Guo, M, Nettles, K.W, Disney, M.D.
登録日2011-07-18
公開日2012-04-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
5DD1
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Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN
著者Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.597 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
5DD0
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Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
分子名称: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB HEAVY LIGHT, oligo peptide
著者Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日2015-08-24
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.488 Å)
主引用文献Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016
4QF1
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Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
著者Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日2014-05-19
公開日2015-02-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
Immunity, 41, 2014
1Q67
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BU of 1q67 by Molmil
Crystal structure of Dcp1p
分子名称: Decapping protein involved in mRNA degradation-Dcp1p
著者She, M, Decker, C.J, Liu, Y, Chen, N, Parker, R, Song, H.
登録日2003-08-12
公開日2004-03-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Dcp1p and its functional implications in mRNA decapping
Nat.Struct.Mol.Biol., 11, 2004
2GJK
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BU of 2gjk by Molmil
Structural and functional insights into the human Upf1 helicase core
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Regulator of nonsense transcripts 1
著者Cheng, Z, Muhlrad, D, Parker, R, Song, H.
登録日2006-03-31
公開日2007-01-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and functional insights into the human Upf1 helicase core
Embo J., 26, 2007
2GK6
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BU of 2gk6 by Molmil
Structural and Functional insights into the human Upf1 helicase core
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Cheng, Z, Muhlrad, D, Parker, R, Song, H.
登録日2006-03-31
公開日2007-01-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and functional insights into the human Upf1 helicase core
Embo J., 26, 2007
2GK7
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BU of 2gk7 by Molmil
Structural and Functional insights into the human Upf1 helicase core
分子名称: PHOSPHATE ION, Regulator of nonsense transcripts 1
著者Cheng, Z, Muhlrad, D, Parker, R, Song, H.
登録日2006-03-31
公開日2007-01-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and functional insights into the human Upf1 helicase core
Embo J., 26, 2007
7UD6
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BU of 7ud6 by Molmil
Designed Enzyme SH3-588 (Catechol O-methyltransferase catalytic domain and Src homology 3 binding domain fusion)
分子名称: POTASSIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, Tyrosine-protein kinase Fyn,Catechol O-methyltransferase
著者Ongpipattanakul, C, Nair, S.K.
登録日2022-03-18
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Designer installation of a substrate recruitment domain to tailor enzyme specificity.
Nat.Chem.Biol., 19, 2023
7TC5
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BU of 7tc5 by Molmil
All Phe-Azurin variant - F15Y
分子名称: Azurin, COPPER (II) ION, NITRATE ION, ...
著者Fedoretz-Maxwell, B.P, Worrall, L.J, Strynadka, N.C.J, Warren, J.J.
登録日2021-12-22
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins.
Inorg.Chem., 61, 2022
7TC6
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All Phe-Azurin variant - F15W
分子名称: Azurin, COPPER (II) ION, NITRATE ION
著者Fedoretz-Maxwell, B.P, Worrall, L.J, Strynadka, N.C.J, Warren, J.J.
登録日2021-12-22
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins.
Inorg.Chem., 61, 2022
5IIE
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STRUCTURE OF THE UNLIGANDED ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3
分子名称: antibody DH501 FabH chain, antibody DH501 light chain
著者Nicely, N.I, Haynes, B.F.
登録日2016-03-01
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.
Cell Rep, 18, 2017
5T4Z
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BU of 5t4z by Molmil
STRUCTURE OF THE ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3 WITH FREE MAN9 GLYCAN
分子名称: CALCIUM ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, antibody DH501 Fab heavy chain, ...
著者Nicely, N.I, Haynes, B.F.
登録日2016-08-30
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates.
Cell Rep, 18, 2017
7TEI
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BU of 7tei by Molmil
SARS-CoV-2 Omicron 1-RBD up Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Stalls, V, Acharya, P.
登録日2022-01-05
公開日2022-02-16
最終更新日2023-04-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural diversity of the SARS-CoV-2 Omicron spike.
Mol.Cell, 82, 2022
7TF8
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SARS-CoV-2 Omicron 3-RBD down Spike Protein Trimer without the P986-P987 stabilizing mutations (S-GSAS-Omicron)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Stalls, V, Acharya, P.
登録日2022-01-06
公開日2022-02-16
最終更新日2023-04-12
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural diversity of the SARS-CoV-2 Omicron spike.
Mol.Cell, 82, 2022
5VL4
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Accidental minimum contact crystal lattice formed by a redesigned protein oligomer
分子名称: T33-53H-B
著者Cannon, K.A, Cascio, D, Sawaya, M.R, Park, R, Boyken, S, King, N, Yeates, T.
登録日2017-04-24
公開日2018-05-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering.
Protein Sci., 29, 2020
5CY5
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BU of 5cy5 by Molmil
Crystal structure of the T33-51H designed self-assembling protein tetrahedron
分子名称: T33-51H-A, T33-51H-B
著者Cannon, K.A, Cascio, D, Park, R, Boyken, S, King, N, Yeates, T.O.
登録日2015-07-30
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering.
Protein Sci., 29, 2020
4ZK7
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Crystal structure of rescued two-component self-assembling tetrahedral cage T33-31
分子名称: Chorismate mutase, Divalent-cation tolerance protein CutA
著者Liu, Y, Cascio, D, Sawaya, M.R, Bale, J, Collazo, M.J, Park, R, King, N, Baker, D, Yeates, T.
登録日2015-04-30
公開日2015-07-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression.
Protein Sci., 24, 2015
8SAN
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BU of 8san by Molmil
CryoEM structure of VRC01-CH848.0836.10
分子名称: CH848.0836.10 gp120, CH848.0836.10 gp41, VCR01 variable heavy chain, ...
著者Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日2023-04-01
公開日2023-04-19
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SAY
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BU of 8say by Molmil
CryoEM structure of DH270.3-CH848.10.17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ...
著者Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日2023-04-02
公開日2023-04-19
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SAU
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CryoEM structure of DH270.4-CH848.10.17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ...
著者Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
登録日2023-04-02
公開日2023-04-19
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023

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