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5XIX
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BU of 5xix by Molmil
The canonical domain of human asparaginyl-tRNA synthetase
分子名称: Asparagine--tRNA ligase, cytoplasmic, GLYCEROL
著者Park, J.S, Han, B.W.
登録日2017-04-28
公開日2018-05-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity.
Int. J. Biol. Macromol., 120, 2018
3TD5
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BU of 3td5 by Molmil
Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with L-Ala-gamma-D-Glu-m-DAP-D-Ala-D-Ala
分子名称: CHLORIDE ION, Outer membrane protein omp38, peptide(L-Ala-gamma-D-Glu-m-DAP-D-Ala-D-Ala)
著者Park, J.S, Lee, W.C, Song, J.H, Kim, H.Y.
登録日2011-08-10
公開日2011-10-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Faseb J., 26, 2012
3TD4
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BU of 3td4 by Molmil
Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with diaminopimelate
分子名称: 2,6-DIAMINOPIMELIC ACID, Outer membrane protein omp38
著者Park, J.S, Lee, W.C, Song, J.H, Kim, H.Y.
登録日2011-08-10
公開日2011-10-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Faseb J., 26, 2012
3TD3
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BU of 3td3 by Molmil
Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with glycine
分子名称: GLYCINE, Outer membrane protein omp38
著者Park, J.S, Lee, W.C, Song, J.H, Kim, H.Y.
登録日2011-08-10
公開日2011-10-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Faseb J., 26, 2012
4ZYA
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BU of 4zya by Molmil
The N-terminal extension domain of human asparaginyl-tRNA synthetase
分子名称: Asparagine--tRNA ligase, cytoplasmic, CHLORIDE ION, ...
著者Park, J.S, Park, M.C, Goughnour, P, Kim, H.S, Kim, S.J, Kim, H.J, Kim, S.H, Han, B.W.
登録日2015-05-21
公開日2016-05-25
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity.
Int. J. Biol. Macromol., 120, 2018
7TYD
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BU of 7tyd by Molmil
Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder in P21 space group
分子名称: Binder, Fibroblast growth factor receptor 4
著者Park, J.S, Lee, S.
登録日2022-02-12
公開日2022-11-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein.
Cell Rep, 41, 2022
6K8C
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BU of 6k8c by Molmil
Crystal structure of Helicobacter pylori folylpolyglutamate synthetase
分子名称: CITRIC ACID, Folylpolyglutamate synthase (FolC), GLYCEROL
著者Park, J.S, Han, B.W.
登録日2019-06-11
公開日2019-11-06
実験手法X-RAY DIFFRACTION (1.95174968 Å)
主引用文献Structural Analyses of Helicobacter Pylori FolC Conducting Glutamation in Folate Metabolism.
Crystals, 2019
6A0H
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BU of 6a0h by Molmil
Crystal structure of human protein N-terminal asparagine amidohydrolase (NTAN1) C75S mutant with Asn-Leu-Ala-Ala-Arg peptide
分子名称: 5-mer peptide ASN-LEU-ALA-ALA-ARG, GLYCEROL, PHOSPHATE ION, ...
著者Park, J.S, Han, B.W.
登録日2018-06-05
公開日2019-12-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.185 Å)
主引用文献Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway.
Biomolecules, 10, 2020
6A0F
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BU of 6a0f by Molmil
Crystal structure of human protein N-terminal asparagine amidohydrolase (NTAN1) C75S mutant with Asn-Phe-Ala-Ala-Arg peptide
分子名称: 5-mer peptide Asn-Phe-Ala-Ala-Arg, GLYCEROL, PHOSPHATE ION, ...
著者Park, J.S, Han, B.W.
登録日2018-06-05
公開日2019-12-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.384 Å)
主引用文献Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway.
Biomolecules, 10, 2020
6A0E
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BU of 6a0e by Molmil
Crystal structure of human protein N-terminal asparagine amidohydrolase (NTAN1)
分子名称: GLYCEROL, PHOSPHATE ION, Protein N-terminal asparagine amidohydrolase
著者Park, J.S, Han, B.W.
登録日2018-06-05
公開日2019-12-11
最終更新日2020-06-24
実験手法X-RAY DIFFRACTION (1.947 Å)
主引用文献Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway.
Biomolecules, 10, 2020
6A0I
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BU of 6a0i by Molmil
Crystal structure of human protein N-terminal asparagine amidohydrolase (NTAN1) C75S mutant
分子名称: GLYCEROL, PHOSPHATE ION, Protein N-terminal asparagine amidohydrolase
著者Park, J.S, Han, B.W.
登録日2018-06-05
公開日2019-12-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Structural Analyses on the Deamidation of N-Terminal Asn in the Human N-Degron Pathway.
Biomolecules, 10, 2020
2BGG
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BU of 2bgg by Molmil
The structure of a Piwi protein from Archaeoglobus fulgidus complexed with a 16nt siRNA duplex.
分子名称: 5'-R(*GP*UP*CP*GP*AP*AP*UP*UP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*GP*CP)-3', MANGANESE (II) ION, ...
著者Parker, J.S, Roe, S.M, Barford, D.
登録日2004-12-22
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Insights Into Mrna Recognition from a Piwi Domain-Sirna Guide Complex
Nature, 434, 2005
2W42
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BU of 2w42 by Molmil
THE STRUCTURE OF A PIWI PROTEIN FROM ARCHAEOGLOBUS FULGIDUS COMPLEXED WITH A 16NT DNA DUPLEX.
分子名称: 5'-D(*GP*TP*CP*GP*AP*AP*TP*TP)-3', 5'-D(*TP*TP*CP*GP*AP*CP*GP*CP)-3', MANGANESE (II) ION, ...
著者Parker, J.S, Roe, S.M, Barford, D.
登録日2008-11-19
公開日2008-12-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Enhancement of the Seed-Target Recognition Step in RNA Silencing by a Piwi-Mid Domain Protein
Mol.Cell, 33, 2009
1W9H
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BU of 1w9h by Molmil
The Structure of a Piwi protein from Archaeoglobus fulgidus.
分子名称: CADMIUM ION, CHLORIDE ION, HYPOTHETICAL PROTEIN AF1318, ...
著者Parker, J.S, Roe, S.M, Barford, D.
登録日2004-10-13
公開日2005-01-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of a Piwi Protein Suggests Mechanisms for Sirna Recognition and Slicer Activity
Embo J., 23, 2004
8H53
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BU of 8h53 by Molmil
Human asparaginyl-tRNA synthetase in complex with asparagine-AMP
分子名称: 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparagine--tRNA ligase, cytoplasmic, ...
著者Park, J.S, Han, B.W.
登録日2022-10-12
公開日2023-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
7N1J
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BU of 7n1j by Molmil
Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder
分子名称: Binder, Fibroblast growth factor receptor 4
著者Park, J.S, Lee, S.
登録日2021-05-27
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7N1K
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BU of 7n1k by Molmil
Crystal structure of a de novo-designed mini-protein targeting FGFR
分子名称: Binder
著者Park, J.S, Lee, S.
登録日2021-05-27
公開日2022-04-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
6VL4
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BU of 6vl4 by Molmil
Crystal Structure of mPGES-1 bound to DG-031
分子名称: (2R)-cyclopentyl{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid, Prostaglandin E synthase, TETRAETHYLENE GLYCOL, ...
著者Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H.
登録日2020-01-22
公開日2020-12-02
最終更新日2020-12-16
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP).
Biochim Biophys Acta Gen Subj, 1865, 2020
6VGI
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BU of 6vgi by Molmil
Crystal Structures of FLAP bound to MK-866
分子名称: 3-[3-(tert-butylsulfanyl)-1-[(4-chlorophenyl)methyl]-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid, 5-lipoxygenase-activating protein, SULFATE ION
著者Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H.
登録日2020-01-08
公開日2020-12-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP).
Biochim Biophys Acta Gen Subj, 1865, 2020
6VGC
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BU of 6vgc by Molmil
Crystal Structures of FLAP bound to DG-031
分子名称: (2R)-cyclopentyl{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid, 5-lipoxygenase-activating protein, CALCIUM ION, ...
著者Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H.
登録日2020-01-07
公開日2020-12-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP).
Biochim Biophys Acta Gen Subj, 1865, 2020
4G4W
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BU of 4g4w by Molmil
Crystal structure of peptidoglycan-associated lipoprotein from Acinetobacter baumannii
分子名称: ALANINE, GLYCEROL, Peptidoglycan-associated lipoprotein, ...
著者Lee, W.C, Song, J.H, Park, J.S, Kim, H.Y.
登録日2012-07-16
公開日2013-07-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Enantiomer-dependent amino acid binding affinity of OmpA-like domains from Acinetobacter baumannii peptidoglycan-associated lipoprotein and OmpA
to be published
4G4V
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BU of 4g4v by Molmil
Crystal structure of peptidoglycan-associated lipoprotein from Acinetobacter baumannii
分子名称: 2,6-DIAMINOPIMELIC ACID, Peptidoglycan-associated lipoprotein
著者Lee, W.C, Song, J.H, Park, J.S, Kim, H.Y.
登録日2012-07-16
公開日2013-07-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Enantiomer-dependent amino acid binding affinity of OmpA-like domains from Acinetobacter baumannii peptidoglycan-associated lipoprotein and OmpA
To be Published
4G4Y
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BU of 4g4y by Molmil
Crystal structure of OmpA peptidoglycan-binding domain from Acinetobacter baumannii
分子名称: ALANINE, Outer membrane protein Omp38, SULFATE ION
著者Lee, W.C, Song, J.H, Park, J.S, Kim, H.Y.
登録日2012-07-16
公開日2013-07-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Enantiomer-dependent amino acid binding affinity of OmpA-like domains from Acinetobacter baumannii peptidoglycan-associated lipoprotein and OmpA
To be Published
4G4X
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BU of 4g4x by Molmil
Crystal structure of peptidoglycan-associated lipoprotein from Acinetobacter baumannii
分子名称: D-ALANINE, GLYCEROL, Peptidoglycan-associated lipoprotein, ...
著者Lee, W.C, Song, J.H, Park, J.S, Kim, H.Y.
登録日2012-07-16
公開日2013-07-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Enantiomer-dependent amino acid binding affinity of OmpA-like domains from Acinetobacter baumannii peptidoglycan-associated lipoprotein and OmpA
To be Published
4G88
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BU of 4g88 by Molmil
Crystal structure of OmpA peptidoglycan-binding domain from Acinetobacter baumannii
分子名称: 2,6-DIAMINOPIMELIC ACID, Outer membrane protein Omp38, S,R MESO-TARTARIC ACID
著者Lee, W.C, Song, J.H, Park, J.S, Kim, H.Y.
登録日2012-07-22
公開日2013-07-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Enantiomer-dependent amino acid binding affinity of OmpA-like domains from Acinetobacter baumannii peptidoglycan-associated lipoprotein and OmpA
to be published

 

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