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3UGB
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BU of 3ugb by Molmil
UbcH5c~Ubiquitin Conjugate
分子名称: GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3
著者Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S.
登録日2011-11-02
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.
Biochemistry, 51, 2012
3RGH
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BU of 3rgh by Molmil
Structure of filamin A immunoglobulin-like repeat 10 from Homo sapiens
分子名称: ACETATE ION, Filamin-A
著者Page, R.C, Clark, J, Misra, S.
登録日2011-04-08
公開日2011-08-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structure of filamin A immunoglobulin-like repeat 10 from Homo sapiens.
Acta Crystallogr.,Sect.F, 67, 2011
3TGD
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BU of 3tgd by Molmil
Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b
分子名称: Ubiquitin-conjugating enzyme E2 D2
著者Page, R.C, Amick, J, Misra, S.
登録日2011-08-17
公開日2011-08-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the human ubiquitin-conjugating enzyme (E2) UbcH5b
To be Published
2K3M
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BU of 2k3m by Molmil
Rv1761c
分子名称: Rv1761c, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
著者Page, R.C, Moore, J.D, Lee, S, Opella, S.J, Cross, T.A.
登録日2008-05-14
公開日2009-01-06
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Backbone structure of a small helical integral membrane protein: A unique structural characterization.
Protein Sci., 18, 2009
4GKY
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BU of 4gky by Molmil
Crystal structure of a carbohydrate-binding domain
分子名称: CALCIUM ION, GLYCEROL, Protein ERGIC-53, ...
著者Page, R.C, Zheng, C, Nix, J.C, Misra, S, Zhang, B.
登録日2012-08-13
公開日2013-06-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4201 Å)
主引用文献Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII).
J.Biol.Chem., 288, 2013
4GKX
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BU of 4gkx by Molmil
Crystal structure of a carbohydrate-binding domain
分子名称: CALCIUM ION, GLYCEROL, Protein ERGIC-53, ...
著者Page, R.C, Zheng, C, Nix, J.C, Misra, S, Zhang, B.
登録日2012-08-13
公開日2013-06-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Characterization of Carbohydrate Binding by LMAN1 Protein Provides New Insight into the Endoplasmic Reticulum Export of Factors V (FV) and VIII (FVIII).
J.Biol.Chem., 288, 2013
3R6B
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BU of 3r6b by Molmil
Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3
分子名称: 1,2-ETHANEDIOL, Thrombospondin-1
著者Page, R.C, Klenotic, P.A, Misra, S, Silverstein, R.L.
登録日2011-03-21
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.
Protein Expr.Purif., 80, 2011
6OP7
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BU of 6op7 by Molmil
Structure of oxidized VIM-20
分子名称: ACETATE ION, Metallo-beta-lactamase VIM-20, ZINC ION
著者Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C.
登録日2019-04-24
公開日2019-10-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Mbio, 10, 2019
4KBQ
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BU of 4kbq by Molmil
Structure of the CHIP-TPR domain in complex with the Hsc70 Lid-Tail domains
分子名称: E3 ubiquitin-protein ligase CHIP, Heat shock cognate 71 kDa protein
著者Page, R.C, Amick, J, Nix, J.C, Misra, S.
登録日2013-04-23
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献A Bipartite Interaction between Hsp70 and CHIP Regulates Ubiquitination of Chaperoned Client Proteins.
Structure, 23, 2015
6CQS
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BU of 6cqs by Molmil
Sediminispirochaeta smaragdinae SPS-1 metallo-beta-lactamase
分子名称: Beta-lactamase, ZINC ION
著者Page, R.C, VanPelt, J, Cheng, Z, Crowder, M.W.
登録日2018-03-16
公開日2018-08-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Noncanonical Metal Center Drives the Activity of the Sediminispirochaeta smaragdinae Metallo-beta-lactamase SPS-1.
Biochemistry, 57, 2018
6NHK
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BU of 6nhk by Molmil
Mortalin nucleotide binding domain in the ADP-bound state
分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Page, R.C, Moseng, M.A, Nix, J.C.
登録日2018-12-23
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.777 Å)
主引用文献Biophysical Consequences of EVEN-PLUS Syndrome Mutations for the Function of Mortalin.
J.Phys.Chem.B, 123, 2019
6OP6
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BU of 6op6 by Molmil
Structure of VIM-20 in the reduced state
分子名称: Metallo-beta-lactamase VIM-20, SODIUM ION, ZINC ION
著者Page, R.C, Shurina, B.A, Montgomery, J.S, Orischak, M.G, Nix, J.C.
登録日2019-04-24
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Mbio, 10, 2019
4NQ2
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BU of 4nq2 by Molmil
Structure of Zn(II)-bound metallo-beta-lactamse VIM-2 from Pseudomonas aeruginosa
分子名称: ACETATE ION, Beta-lactamase class B VIM-2, ZINC ION
著者Aitha, M, Nix, J.C, Crowder, M.W, Page, R.C.
登録日2013-11-23
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Biochemical, Mechanistic, and Spectroscopic Characterization of Metallo-beta-lactamase VIM-2.
Biochemistry, 53, 2014
6P2U
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BU of 6p2u by Molmil
Structure of Mortalin-NBD with N6-propargyladenosine-5'-diphosphate
分子名称: 9-{5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-alpha-D-ribofuranosyl}-N-(prop-2-yn-1-yl)-9H-purin-6-amine, MAGNESIUM ION, PHOSPHATE ION, ...
著者Moseng, M.A, Page, R.C.
登録日2019-05-22
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献2- and N6-functionalized adenosine-5'-diphosphate analogs for the inhibition of mortalin.
Febs Lett., 593, 2019
6PMT
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BU of 6pmt by Molmil
Structure of Mortalin-NBD with adenosine-5'-monophosphate and thiodiphosphate
分子名称: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Stress-70 protein, ...
著者Moseng, M.A, Nix, J.C, Page, R.C.
登録日2019-07-02
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the mortalin nucleotide binding domain in complex with adenosine monophosphate
to be published
5F16
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BU of 5f16 by Molmil
CTA-modified hen egg-white lysozyme
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者McGlone, C, Nix, J.C, Page, R.C.
登録日2015-11-30
公開日2016-02-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates.
Biomacromolecules, 17, 2016
5F14
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BU of 5f14 by Molmil
Structure of native hen egg-white lysozyme
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者McGlone, C, Nix, J.C, Page, R.C.
登録日2015-11-30
公開日2016-02-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.148 Å)
主引用文献Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates.
Biomacromolecules, 17, 2016
2KNC
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BU of 2knc by Molmil
Platelet integrin ALFAIIB-BETA3 transmembrane-cytoplasmic heterocomplex
分子名称: Integrin alpha-IIb, Integrin beta-3
著者Yang, J, Ma, Y, Page, R.C, Misra, S, Plow, E.F, Qin, J.
登録日2009-08-20
公開日2009-09-29
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.
Proc.Natl.Acad.Sci.USA, 106, 2009
5WIH
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BU of 5wih by Molmil
Structure of New Delhi Metallo-Beta-lactamase 12 (NDM-12)
分子名称: Metallo-beta-lactamase NDM-12, ZINC ION
著者VanPelt, J, Williams, C, Page, R.C.
登録日2017-07-19
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Clinical Variants of New Delhi Metallo-beta-Lactamase Are Evolving To Overcome Zinc Scarcity.
Acs Infect Dis., 3, 2017
5WIG
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BU of 5wig by Molmil
Structure of New Delhi Metallo-Beta-lactamase 4 (NDM-4)
分子名称: NDM-4, ZINC ION
著者VanPelt, J, Williams, C, Page, R.C.
登録日2017-07-19
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Clinical Variants of New Delhi Metallo-beta-Lactamase Are Evolving To Overcome Zinc Scarcity.
Acs Infect Dis., 3, 2017
4JS9
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BU of 4js9 by Molmil
Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, Mesoheme, Nitric oxide synthase, ...
著者Hannibal, L, Page, R.C, Bolisetty, K, Yu, Z, Misra, S, Stuehr, D.J.
登録日2013-03-22
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.784 Å)
主引用文献Kinetic and Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme
To be Published
3DWJ
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BU of 3dwj by Molmil
Heme-proximal W188H mutant of inducible nitric oxide synthase
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, AMMONIUM ION, Nitric oxide synthase, ...
著者Tejero, J, Biswas, A, Wang, Z.-Q, Haque, M.M, Hemann, C, Zweier, J.L, Page, R.C, Misra, S, Stuehr, D.J.
登録日2008-07-22
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Stabilization and Characterization of a Heme-Oxy Reaction Intermediate in Inducible Nitric-oxide Synthase
J.Biol.Chem., 283, 2008
4KBO
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BU of 4kbo by Molmil
Crystal structure of the human Mortalin (GRP75) ATPase domain in the apo form
分子名称: SODIUM ION, Stress-70 protein, mitochondrial
著者Amick, J, Page, R.C, Nix, J.C, Misra, S.
登録日2013-04-23
公開日2014-04-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone.
Protein Sci., 23, 2014
8SUV
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BU of 8suv by Molmil
CHIP-TPR in complex with the C-terminus of CHIC2
分子名称: Cysteine-rich hydrophobic domain-containing protein 2, E3 ubiquitin-protein ligase CHIP, SULFATE ION
著者Cupo, A.R, McDermott, L.E, DeSilva, A.R, Callahan, M, Nix, J.C, Gestwicki, J.E, Page, R.C.
登録日2023-05-13
公開日2024-03-20
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Interaction with the membrane-anchored protein CHIC2 constrains the ubiquitin ligase activity of CHIP
Biorxiv, 2023
3ISW
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BU of 3isw by Molmil
Crystal structure of filamin-A immunoglobulin-like repeat 21 bound to an N-terminal peptide of CFTR
分子名称: Cystic fibrosis transmembrane conductance regulator, Filamin-A
著者Xu, Z, Page, R, Qin, J, Ithychanda, S.S, Liu, J.M, Misra, S.
登録日2009-08-27
公開日2010-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Biochemical basis of the interaction between cystic fibrosis transmembrane conductance regulator and immunoglobulin-like repeats of filamin.
J.Biol.Chem., 285, 2010

 

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