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6DQL
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BU of 6dql by Molmil
Crystal structure of Regulator of Proteinase B RopB complexed with SIP
分子名称: Regulator of Proteinase B RopB, SpeB-inducing peptide (SIP)
著者Do, H, Makthal, N, VanderWal, A.R, Olsen, R.J, Musser, J.M, Kumaraswami, M.
登録日2018-06-11
公開日2019-05-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Environmental pH and peptide signaling control virulence of Streptococcus pyogenes via a quorum-sensing pathway.
Nat Commun, 10, 2019
2AVW
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BU of 2avw by Molmil
Crystal structure of monoclinic form of streptococcus Mac-1
分子名称: GLYCEROL, IgG-degrading protease, SULFATE ION
著者Agniswamy, J, Nagiec, M.J, Liu, M, Schuck, P, Musser, J.M, Sun, P.D.
登録日2005-08-30
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of group a streptococcus mac-1: insight into dimer-mediated specificity for recognition of human IgG.
Structure, 14, 2006
2AU1
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BU of 2au1 by Molmil
Crystal Structure of group A Streptococcus MAC-1 orthorhombic form
分子名称: BETA-MERCAPTOETHANOL, IgG-degrading protease
著者Agniswamy, J, Nagiec, M.J, Liu, M, Schuck, P, Musser, J.M, Sun, P.D.
登録日2005-08-26
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of group a streptococcus mac-1: insight into dimer-mediated specificity for recognition of human IgG.
Structure, 14, 2006
1DKI
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BU of 1dki by Molmil
CRYSTAL STRUCTURE OF THE ZYMOGEN FORM OF STREPTOCOCCAL PYROGENIC EXOTOXIN B ACTIVE SITE (C47S) MUTANT
分子名称: PYROGENIC EXOTOXIN B ZYMOGEN, SULFATE ION
著者Kagawa, T.F, Cooney, J.C, Baker, H.M, McSweeney, S, Liu, M, Gubba, S, Musser, J.M, Baker, E.N.
登録日1999-12-07
公開日2000-03-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: an integrin-binding cysteine protease.
Proc.Natl.Acad.Sci.USA, 97, 2000
1P44
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BU of 1p44 by Molmil
Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data
分子名称: 5-{[4-(9H-FLUOREN-9-YL)PIPERAZIN-1-YL]CARBONYL}-1H-INDOLE, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kuo, M.R, Morbidoni, H.R, Alland, D, Sneddon, S.F, Gourlie, B.B, Staveski, M.M, Leonard, M, Gregory, J.S, Janjigian, A.D, Yee, C, Musser, J.M, Kreiswirth, B, Iwamoto, H, Perozzo, R, Jacobs Jr, W.R, Sacchettini, J.C, Fidock, D.A, TB Structural Genomics Consortium (TBSGC)
登録日2003-04-21
公開日2003-09-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data.
J.Biol.Chem., 278, 2003
1P45
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Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data
分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN
著者Kuo, M.R, Morbidoni, H.R, Alland, D, Sneddon, S.F, Gourlie, B.B, Staveski, M.M, Leonard, M, Gregory, J.S, Janjigian, A.D, Yee, C, Musser, J.M, Kreiswirth, B.N, Iwamoto, H, Perozzo, R, Jacobs Jr, W.R, Sacchettini, J.C, Fidock, D.A, TB Structural Genomics Consortium (TBSGC)
登録日2003-04-21
公開日2003-09-16
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data.
J.Biol.Chem., 278, 2003
8TMA
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BU of 8tma by Molmil
Antibody N3-1 bound to RBD in the up conformation
分子名称: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-07-29
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8TM1
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BU of 8tm1 by Molmil
Antibody N3-1 bound to RBDs in the up and down conformations
分子名称: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
著者Hsieh, C.-L, McLellan, J.S.
登録日2023-07-27
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
5DL2
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BU of 5dl2 by Molmil
Crystal Structure of RopB
分子名称: Regulator of protease B (RopB)
著者Kumaraswami, M.
登録日2015-09-04
公開日2016-01-20
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural and functional analysis of RopB: a major virulence regulator in Streptococcus pyogenes.
Mol.Microbiol., 99, 2016
6O5C
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BU of 6o5c by Molmil
X-ray crystal structure of metal-dependent transcriptional regulator MtsR
分子名称: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, Putative metal-dependent transcriptional regulator
著者Do, H, Kumaraswami, M.
登録日2019-03-01
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence.
Nucleic Acids Res., 47, 2019
4I7H
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BU of 4i7h by Molmil
Structural basis for peroxide sensing and gene regulation by PerR from Streptococcus pyogenes
分子名称: NICKEL (II) ION, ZINC ION, peroxide stress sensing regulator
著者Kumaraswami, M.
登録日2012-11-30
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Peroxide Stress Regulator from Streptococcus pyogenes Provides Functional Insights into the Mechanism of Oxidative Stress Sensing.
J.Biol.Chem., 288, 2013
3RJP
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BU of 3rjp by Molmil
Crystal structure of the DNA binding domain of CovR from Streptococcus pyogenes
分子名称: CovR
著者Horstmann, N.M, Brennan, R.G, Shelburne, S.A.
登録日2011-04-15
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the DNA binding domain of CovR from Streptococcus pyogenes
To be Published

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件を2024-08-14に公開中

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