2L2I
 
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1T95
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4PQP
 | | Crystal structure of human SNX14 PX domain in space group P43212 | | 分子名称: | GLYCEROL, Sorting nexin-14 | | 著者 | Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B. | | 登録日 | 2014-03-03 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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4PQO
 | | Structure of the human SNX14 PX domain in space group I41 | | 分子名称: | Sorting nexin-14 | | 著者 | Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B. | | 登録日 | 2014-03-03 | | 公開日 | 2014-09-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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5H5U
 | | Mechanistic insights into the alternative translation termination by ArfA and RF2 | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Ma, C, Kurita, D, Li, N, Chen, Y, Himeno, H, Gao, N. | | 登録日 | 2016-11-09 | | 公開日 | 2017-01-25 | | 最終更新日 | 2018-10-24 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanistic insights into the alternative translation termination by ArfA and RF2
Nature, 541, 2017
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4Z9E
 | | Alba from Thermoplasma volcanium | | 分子名称: | DNA/RNA-binding protein Alba | | 著者 | Ma, C, Lee, S.J, Pathak, C, Lee, B.J. | | 登録日 | 2015-04-10 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Alba from Thermoplasma volcanium belongs to alpha-NAT's: An insight into the structural aspects of Tv Alba and its acetylation by Tv Ard1.
Arch.Biochem.Biophys., 590, 2016
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1W70
 | | SH3 domain of p40phox complexed with C-terminal polyProline region of p47phox | | 分子名称: | NEUTROPHIL CYTOSOL FACTOR 1, NEUTROPHIL CYTOSOL FACTOR 4, SULFATE ION, ... | | 著者 | Massenet, C, Chenavas, S, Cohen-Addad, C, Dagher, M.-C, Brandolin, G, Pebay-Peyroula, E, Fieschi, F. | | 登録日 | 2004-08-26 | | 公開日 | 2005-01-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Effects of P47Phox C-Terminus Phosphorylation on Binding Interactions with P40Phox and P67Phox: Structural and Functional Comparison of P40Phox P67Phox SH3 Domains
J.Biol.Chem., 280, 2005
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1W6X
 | | SH3 domain of p40phox, component of the NADPH oxidase | | 分子名称: | NEUTROPHIL CYTOSOL FACTOR 4 | | 著者 | Massenet, C, Chenavas, S, Cohen-Addad, C, Dagher, M.-C, Brandolin, G, Pebay-Peyroula, E, Fieschi, F. | | 登録日 | 2004-08-24 | | 公開日 | 2005-01-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Effects of P47Phox C-Terminus Phosphorylation on Binding Interactions with P40Phox and P67Phox: Structural and Functional Comparison of P40Phox P67Phox SH3 Domains
J.Biol.Chem., 280, 2005
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2NTY
 | | Rop4-GDP-PRONE8 | | 分子名称: | Emb|CAB41934.1, GUANOSINE-5'-DIPHOSPHATE, Rac-like GTP-binding protein ARAC5 | | 著者 | Thomas, C, Fricke, I, Scrima, A, Berken, A, Wittinghofer, A. | | 登録日 | 2006-11-08 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Evidence for a Common Intermediate in Small G Protein-GEF Reactions
Mol.Cell, 25, 2007
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6K6U
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5H4P
 | | Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1 | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Ma, C, Wu, S, Li, N, Chen, Y, Yan, K, Li, Z, Zheng, L, Lei, J, Woolford, J.L, Gao, N. | | 登録日 | 2016-11-01 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1
Nat. Struct. Mol. Biol., 24, 2017
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3BWD
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2WBL
 | | Three-dimensional structure of a binary ROP-PRONE complex | | 分子名称: | RAC-LIKE GTP-BINDING PROTEIN ARAC2, RHO OF PLANTS GUANINE NUCLEOTIDE EXCHANGE FACTOR 8 | | 著者 | Thomas, C, Fricke, I, Weyand, M, Berken, A. | | 登録日 | 2009-03-02 | | 公開日 | 2009-04-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | 3D Structure of a Binary Rop-Prone Complex: The Final Intermediate for a Complete Set of Molecular Snapshots of the Ropgef Reaction.
Biol.Chem., 390, 2009
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3SE4
 | | human IFNw-IFNAR ternary complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon alpha/beta receptor 1, Interferon alpha/beta receptor 2, ... | | 著者 | Thomas, C, Garcia, K.C. | | 登録日 | 2011-06-10 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.5001 Å) | | 主引用文献 | Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
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3S8W
 | | D2 domain of human IFNAR2 | | 分子名称: | CHLORIDE ION, Interferon alpha/beta receptor 2 | | 著者 | Thomas, C, Garcia, K.C. | | 登録日 | 2011-05-31 | | 公開日 | 2011-08-31 | | 最終更新日 | 2012-03-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
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3S98
 | | human IFNAR1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon alpha/beta receptor 1 | | 著者 | Thomas, C, Garcia, K.C. | | 登録日 | 2011-06-01 | | 公開日 | 2011-08-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
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3S9D
 | | binary complex between IFNa2 and IFNAR2 | | 分子名称: | CHLORIDE ION, Interferon alpha-2, Interferon alpha/beta receptor 2 | | 著者 | Thomas, C, Garcia, K.C. | | 登録日 | 2011-06-01 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9999 Å) | | 主引用文献 | Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
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3SE3
 | | human IFNa2-IFNAR ternary complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon alpha 2b, Interferon alpha/beta receptor 1, ... | | 著者 | Thomas, C, Garcia, K.C. | | 登録日 | 2011-06-10 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (4.0001 Å) | | 主引用文献 | Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
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4PV6
 | | Crystal Structure Analysis of Ard1 from Thermoplasma volcanium | | 分子名称: | ACETYL COENZYME *A, COENZYME A, N-terminal acetyltransferase complex subunit [ARD1] | | 著者 | Ma, C, Lee, S.J, Lee, B.J. | | 登録日 | 2014-03-15 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | | 主引用文献 | Structure of Thermoplasma volcanium Ard1 belongs to N-acetyltransferase family member suggesting multiple ligand binding modes with acetyl coenzyme A and coenzyme A.
Biochim.Biophys.Acta, 1844, 2014
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2NTX
 | | Prone8 | | 分子名称: | Emb|CAB41934.1 | | 著者 | Thomas, C, Fricke, I, Scrima, A, Berken, A, Wittinghofer, A. | | 登録日 | 2006-11-08 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Evidence for a Common Intermediate in Small G Protein-GEF Reactions
Mol.Cell, 25, 2007
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4DEP
 | | Structure of the IL-1b signaling complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 beta, Interleukin-1 receptor accessory protein, ... | | 著者 | Thomas, C, Garcia, K.C. | | 登録日 | 2012-01-21 | | 公開日 | 2012-03-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the activating IL-1 receptor signaling complex.
Nat.Struct.Mol.Biol., 19, 2012
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5OPI
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6WTT
 | | Crystals Structure of the SARS-CoV-2 (COVID-19) main protease with inhibitor GC-376 | | 分子名称: | (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ... | | 著者 | Sacco, M, Ma, C, Chen, Y, Wang, J. | | 登録日 | 2020-05-03 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
Cell Res., 30, 2020
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6RAI
 | | Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing occluded conformation | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ... | | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | | 登録日 | 2019-04-06 | | 公開日 | 2019-07-31 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
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6RAL
 | | Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | | 登録日 | 2019-04-06 | | 公開日 | 2019-07-31 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
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