7SHF
 
 | | Cryo-EM structure of GPR158 coupled to the RGS7-Gbeta5 complex | | 分子名称: | (2S)-1-{[(S)-hydroxy{[(1s,2R,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHOLESTEROL, ... | | 著者 | Patil, D.N, Singh, S, Singh, A.K, Martemyanov, K.A. | | 登録日 | 2021-10-08 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of human GPR158 receptor coupled to the RGS7-G beta 5 signaling complex.
Science, 375, 2022
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7SHE
 | | Cryo-EM structure of human GPR158 | | 分子名称: | (2S)-1-{[(S)-hydroxy{[(1s,2R,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHOLESTEROL, ... | | 著者 | Patil, D.N, Singh, S, Singh, A.K, Martemyanov, K.A. | | 登録日 | 2021-10-08 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of human GPR158 receptor coupled to the RGS7-G beta 5 signaling complex.
Science, 375, 2022
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8D1B
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6N9G
 | | Crystal Structure of RGS7-Gbeta5 dimer | | 分子名称: | Guanine nucleotide-binding protein subunit beta-5, Regulator of G-protein signaling 7 | | 著者 | Patil, D.N, Rangarajan, E, Izard, T, Martemyanov, K.A. | | 登録日 | 2018-12-03 | | 公開日 | 2019-01-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.129 Å) | | 主引用文献 | Structural organization of a major neuronal G protein regulator, the RGS7-G beta 5-R7BP complex.
Elife, 7, 2018
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1FNM
 | | STRUCTURE OF THERMUS THERMOPHILUS EF-G H573A | | 分子名称: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Laurberg, M, Kristensen, O, Martemyanov, K, Gudkov, A.T, Nagaev, I, Hughes, D, Liljas, A. | | 登録日 | 2000-08-22 | | 公開日 | 2000-11-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site.
J.Mol.Biol., 303, 2000
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7ZC9
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7ZCB
 | | Human Pikachurin/EGFLAM N-terminal Fibronectin-III (1-2) domains | | 分子名称: | CHLORIDE ION, Pikachurin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Pantalone, S, Savino, S, Viti, L.V, Forneris, F. | | 登録日 | 2022-03-26 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.
Sci.Signal., 16, 2023
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2BV3
 | | Crystal structure of a mutant elongation factor G trapped with a GTP analogue | | 分子名称: | ELONGATION FACTOR G, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T. | | 登録日 | 2005-06-22 | | 公開日 | 2005-08-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of a Mutant Elongation Factor G Trapped with a GTP Analogue.
FEBS Lett., 579, 2005
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2BM0
 | | Ribosomal elongation factor G (EF-G) Fusidic acid resistant mutant T84A | | 分子名称: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T. | | 登録日 | 2005-03-09 | | 公開日 | 2005-05-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Insights Into Fusidic Acid Resistance and Sensitivity in EF-G
J.Mol.Biol., 348, 2005
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2BM1
 | | Ribosomal elongation factor G (EF-G) Fusidic acid resistant mutant G16V | | 分子名称: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T. | | 登録日 | 2005-03-09 | | 公開日 | 2005-05-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Insights Into Fusidic Acid Resistance and Sensitivity in EF-G
J.Mol.Biol., 348, 2005
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8U02
 | | CryoEM structure of D2 dopamine receptor in complex with GoA KE mutant and dopamine | | 分子名称: | D(2) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Krumm, B.E, Kapolka, N.J, Fay, J.F, Roth, B.L. | | 登録日 | 2023-08-28 | | 公開日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state.
Nat Commun, 15, 2024
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8TZQ
 | | CryoEM structure of D2 dopamine receptor in complex with GoA KE Mutant, scFv16, and dopamine | | 分子名称: | D(2) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Krumm, B.E, Kapolka, N.J, Fay, J.F, Roth, B.L. | | 登録日 | 2023-08-27 | | 公開日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state.
Nat Commun, 15, 2024
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6B20
 | | Crystal structure of a complex between G protein beta gamma dimer and an inhibitory Nanobody regulator | | 分子名称: | CHLORIDE ION, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... | | 著者 | Gulati, S, Kiser, P.D, Palczewski, K. | | 登録日 | 2017-09-19 | | 公開日 | 2018-05-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor.
Nat Commun, 9, 2018
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