7SHF
Cryo-EM structure of GPR158 coupled to the RGS7-Gbeta5 complex
Summary for 7SHF
Entry DOI | 10.2210/pdb7shf/pdb |
EMDB information | 25125 25126 |
Descriptor | Isoform 2 of Regulator of G-protein signaling 7, Guanine nucleotide-binding protein subunit beta-5, G-protein coupled receptor 158, ... (6 entities in total) |
Functional Keywords | receptor, complex, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 280181.28 |
Authors | Patil, D.N.,Singh, S.,Singh, A.K.,Martemyanov, K.A. (deposition date: 2021-10-08, release date: 2021-12-01, Last modification date: 2022-01-19) |
Primary citation | Patil, D.N.,Singh, S.,Laboute, T.,Strutzenberg, T.S.,Qiu, X.,Wu, D.,Novick, S.J.,Robinson, C.V.,Griffin, P.R.,Hunt, J.F.,Izard, T.,Singh, A.K.,Martemyanov, K.A. Cryo-EM structure of human GPR158 receptor coupled to the RGS7-G beta 5 signaling complex. Science, 375:86-91, 2022 Cited by PubMed: 34793198DOI: 10.1126/science.abl4732 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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