2OAZ
 
 | | Human Methionine Aminopeptidase-2 Complexed with SB-587094 | | 分子名称: | COBALT (II) ION, N-(2-ISOPROPYLPHENYL)-3-[(2-THIENYLMETHYL)THIO]-1H-1,2,4-TRIAZOL-5-AMINE, human Methionine Amino Peptidase 2 | | 著者 | Marino Jr, J.P, Fisher, P.W, Hofmann, G.A, Kirkpatrick, R, Janson, C.A, Johnson, R.K, Ma, C, Mattern, M, Meek, T.D, Ryan, D, Schulz, C, Smith, W.W, Tew, D.G, Tomazek Jr, T.A, Veber, D.F, Xiong, W.C, Yamamoto, Y, Yamashita, K, Yang, G, Thompson, S.K. | | 登録日 | 2006-12-18 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore.
J.Med.Chem., 50, 2007
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5DA7
 | | monomeric PCNA bound to a small protein inhibitor | | 分子名称: | DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ... | | 著者 | Ladner, J.E, Altieri, A.S, Kelman, Z. | | 登録日 | 2015-08-19 | | 公開日 | 2016-05-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
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5K8A
 | | NIST FAB | | 分子名称: | Heavy chain, humanized Fab Lite chain | | 著者 | Gallagher, D.T, Galvin, C.V, Karageorgos, I, Marino, J.P. | | 登録日 | 2016-05-27 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Data on crystal organization in the structure of the Fab fragment from the NIST reference antibody, RM 8671.
Data Brief, 16, 2018
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5VGP
 | | Fc fragment of human IgG1 antibody, from NIST mAb | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Human Fc fragment with G1F/G0F glycan, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Gallagher, D.T, Galvin, C.V, Karageorgos, I, Marino, J.P. | | 登録日 | 2017-04-11 | | 公開日 | 2018-04-18 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.116 Å) | | 主引用文献 | Structure of the Fc fragment of the NIST reference antibody RM8671.
Acta Crystallogr F Struct Biol Commun, 74, 2018
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6P6D
 | | HUMAN IGG1 FC FRAGMENT, C239 INSERTION MUTANT | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, IgG1 Fc fragment | | 著者 | Gallagher, D.T, Dimasi, N, McCullough, C. | | 登録日 | 2019-06-03 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structure and Dynamics of a Site-Specific Labeled Fc Fragment with Altered Effector Functions.
Pharmaceutics, 11, 2019
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4JNC
 | | Soluble Epoxide Hydrolase complexed with a carboxamide inhibitor | | 分子名称: | 1-[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]-N-[2-(trifluoromethyl)benzyl]piperidine-4-carboxamide, Bifunctional epoxide hydrolase 2 | | 著者 | Shewchuk, L.M. | | 登録日 | 2013-03-15 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase.
Bioorg.Med.Chem.Lett., 23, 2013
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5DAI
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2ACL
 | | Liver X-Receptor alpha Ligand Binding Domain with SB313987 | | 分子名称: | 1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE, Oxysterols receptor LXR-alpha, RETINOIC ACID, ... | | 著者 | Jaye, M.C, Krawiec, J.A, Campobasso, N, Smallwood, A, Qiu, C, Lu, Q, Kerrigan, J.J. | | 登録日 | 2005-07-19 | | 公開日 | 2005-09-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery of substituted maleimides as liver x receptor agonists and determination of a ligand-bound crystal structure.
J.Med.Chem., 48, 2005
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2IJH
 | | Crystal structure analysis of ColE1 ROM mutant F14W | | 分子名称: | Regulatory protein rop | | 著者 | Ladner, J.E. | | 登録日 | 2006-09-29 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | New crystal structures of ColE1 Rom and variants resulting from mutation of a surface exposed residue: Implications for RNA-recognition.
Proteins, 72, 2008
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2IJJ
 | | Crystal structure analysis of ColE1 ROM mutant F14Y | | 分子名称: | Regulatory protein rop | | 著者 | Ladner, J.E. | | 登録日 | 2006-09-29 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | New crystal structures of ColE1 Rom and variants resulting from mutation of a surface exposed residue: Implications for RNA-recognition.
Proteins, 72, 2008
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2IJI
 | | Structure of F14H mutant of ColE1 Rom protein | | 分子名称: | Regulatory protein rop | | 著者 | Struble, E.B. | | 登録日 | 2006-09-29 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | New crystal structures of ColE1 Rom and variants resulting from mutation of a surface exposed residue: Implications for RNA-recognition.
Proteins, 72, 2008
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2IJK
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