2WBY
 
 | | Crystal structure of human insulin-degrading enzyme in complex with insulin | | 分子名称: | INSULIN A CHAIN, INSULIN B CHAIN, INSULIN-DEGRADING ENZYME, ... | | 著者 | Manolopoulou, M, Guo, Q, Malito, E, Schilling, A.B, Tang, W.J. | | 登録日 | 2009-03-06 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme.
J.Biol.Chem., 284, 2009
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2WC0
 | | crystal structure of human insulin degrading enzyme in complex with iodinated insulin | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, INSULIN A CHAIN, INSULIN B CHAIN, ... | | 著者 | Manolopoulou, M, Guo, Q, Malito, E, Schilling, A.B, Tang, W.J. | | 登録日 | 2009-03-06 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular Basis of Catalytic Chamber-Assisted Unfolding and Cleavage of Human Insulin by Human Insulin Degrading Enzyme.
J.Biol.Chem., 284, 2009
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3E4Z
 | | Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II | | 分子名称: | Insulin-degrading enzyme, Insulin-like growth factor II, ZINC ION | | 著者 | Guo, Q, Manolopoulou, M, Tang, W.-J. | | 登録日 | 2008-08-12 | | 公開日 | 2009-08-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol., 395, 2010
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3E50
 | | Crystal structure of human insulin degrading enzyme in complex with transforming growth factor-alpha | | 分子名称: | Insulin-degrading enzyme, Protransforming growth factor alpha, ZINC ION | | 著者 | Guo, Q, Manolopoulou, M, Tang, W.-J. | | 登録日 | 2008-08-12 | | 公開日 | 2009-08-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol., 395, 2010
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3HGZ
 | | Crystal structure of human insulin-degrading enzyme in complex with amylin | | 分子名称: | Insulin-degrading enzyme, Islet amyloid polypeptide, ZINC ION | | 著者 | Guo, Q, Bian, Y, Tang, W.J. | | 登録日 | 2009-05-14 | | 公開日 | 2009-12-08 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol., 395, 2010
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2JG4
 | | Substrate-free IDE structure in its closed conformation | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, INSULIN DEGRADING ENZYME, ZINC ION | | 著者 | Malito, E, Tang, W.J. | | 登録日 | 2007-02-07 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of Substrate-Free Human Insulin Degrading Enzyme (Ide) and Biophysical Analysis of ATP-Induced Conformational Switch of Ide
J.Biol.Chem., 282, 2007
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2JBU
 | | Crystal structure of human insulin degrading enzyme complexed with co- purified peptides. | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, CO-PURIFIED PEPTIDE, INSULIN-DEGRADING ENZYME | | 著者 | Im, H, Shen, Y, Tang, W.J. | | 登録日 | 2006-12-11 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of Substrate-Free Human Insulin Degrading Enzyme (Ide) and Biophysical Analysis of ATP-Induced Conformational Switch of Ide
J.Biol.Chem., 282, 2007
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3E4A
 | | Human IDE-inhibitor complex at 2.6 angstrom resolution | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, ACETIC ACID, HYDROXAMATE PEPTIDE II1, ... | | 著者 | Malito, E, Leissring, M.A, Choi, S, Cuny, G.D, Tang, W.J. | | 登録日 | 2008-08-11 | | 公開日 | 2009-05-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.
Plos One, 5, 2010
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3CWW
 | | Crystal Structure of IDE-bradykinin complex | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, ACETATE ION, Insulin-degrading enzyme, ... | | 著者 | Malito, E, Tang, W.J. | | 登録日 | 2008-04-23 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme
Biochemistry, 47, 2008
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2WK3
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