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2HLQ
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BU of 2hlq by Molmil
Crystal Structure of the Extracellular Domain of the Type II BMP Receptor
分子名称: Bone morphogenetic protein receptor type-2
著者Mace, P.D, Cutfield, J.F, Cutfield, S.M.
登録日2006-07-09
公開日2006-11-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献High resolution structures of the bone morphogenetic protein type II receptor in two crystal forms: Implications for ligand binding
Biochem.Biophys.Res.Commun., 351, 2006
2HLR
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BU of 2hlr by Molmil
Crystal Structure of the Extracellular Domain of the Type II BMP Receptor
分子名称: Bone morphogenetic protein receptor type-2
著者Mace, P.D, Cutfield, J.F, Cutfield, S.M.
登録日2006-07-10
公開日2006-11-28
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献High resolution structures of the bone morphogenetic protein type II receptor in two crystal forms: Implications for ligand binding
Biochem.Biophys.Res.Commun., 351, 2006
3M1D
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BU of 3m1d by Molmil
Structure of BIR1 from cIAP1
分子名称: Baculoviral IAP repeat-containing protein 2, ZINC ION
著者Mace, P.D, Day, C.L.
登録日2010-03-04
公開日2010-05-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Asymmetric recruitment of cIAPs by TRAF2
J.Mol.Biol., 400, 2010
3T6G
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BU of 3t6g by Molmil
Structure of the complex between NSP3 (SHEP1) and p130Cas
分子名称: ACETATE ION, Breast cancer anti-estrogen resistance protein 1, SH2 domain-containing protein 3C
著者Mace, P.D, Robinson, H, Riedl, S.J.
登録日2011-07-28
公開日2011-11-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.
Nat.Struct.Mol.Biol., 18, 2011
3T6A
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BU of 3t6a by Molmil
Structure of the C-terminal domain of BCAR3
分子名称: (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL, Breast cancer anti-estrogen resistance protein 3, UNKNOWN ATOM OR ION
著者Mace, P.D, Robinson, H, Riedl, S.J.
登録日2011-07-28
公開日2011-11-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling.
Nat.Struct.Mol.Biol., 18, 2011
4IZA
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BU of 4iza by Molmil
Structure of Dually Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain
分子名称: Astrocytic phosphoprotein PEA-15, Mitogen-activated protein kinase 1
著者Mace, P.D, Robinson, H, Riedl, S.J.
登録日2013-01-29
公開日2013-04-10
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK.
Nat Commun, 4, 2013
4IZ5
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BU of 4iz5 by Molmil
Structure of the complex between ERK2 phosphomimetic mutant and PEA-15
分子名称: ADENOSINE-5'-DIPHOSPHATE, Astrocytic phosphoprotein PEA-15, Mitogen-activated protein kinase 1, ...
著者Mace, P.D, Robinson, H, Riedl, S.J.
登録日2013-01-29
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK.
Nat Commun, 4, 2013
4IZ7
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BU of 4iz7 by Molmil
Structure of Non-Phosphorylated ERK2 bound to the PEA-15 Death Effector Domain
分子名称: Astrocytic phosphoprotein PEA-15, Mitogen-activated protein kinase 1, SODIUM ION
著者Mace, P.D, Robinson, H, Riedl, S.J.
登録日2013-01-29
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK.
Nat Commun, 4, 2013
3EB6
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BU of 3eb6 by Molmil
Structure of the cIAP2 RING domain bound to UbcH5b
分子名称: Baculoviral IAP repeat-containing protein 3, Ubiquitin-conjugating enzyme E2 D2, ZINC ION
著者Mace, P.D, Linke, K, Schumacher, F.-R, Smith, C.A, Day, C.L.
登録日2008-08-27
公開日2008-09-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment.
J.Biol.Chem., 283, 2008
3EB5
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BU of 3eb5 by Molmil
Structure of the cIAP2 RING domain
分子名称: Baculoviral IAP repeat-containing protein 3, SODIUM ION, ZINC ION
著者Mace, P.D, Linke, K, Smith, C.A, Day, C.L.
登録日2008-08-27
公開日2008-09-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment.
J.Biol.Chem., 283, 2008
2VJF
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BU of 2vjf by Molmil
Crystal Structure of the MDM2-MDMX RING Domain Heterodimer
分子名称: CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ...
著者Mace, P.D, Linke, K, Smith, C.A, Day, C.L.
登録日2007-12-10
公開日2008-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans.
Cell Death Differ., 15, 2008
2VJE
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BU of 2vje by Molmil
Crystal Structure of the MDM2-MDMX RING Domain Heterodimer
分子名称: CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ...
著者Mace, P.D, Linke, K, Smith, C.A, Day, C.L.
登録日2007-12-10
公開日2008-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans.
Cell Death Differ., 15, 2008
5CEK
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BU of 5cek by Molmil
Pseudokinase domain of Human Tribbles Homolog 1
分子名称: Tribbles homolog 1
著者Mace, P.D, Nakatani, Y.
登録日2015-07-07
公開日2015-11-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Mechanism of CCAAT-Enhancer Binding Protein Recruitment by the TRIB1 Pseudokinase.
Structure, 23, 2015
5CEM
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BU of 5cem by Molmil
Pseudokinase and C-terminal extension of Human Tribbles Homolog 1
分子名称: SULFATE ION, Tribbles homolog 1
著者Mace, P.D, Nakatani, Y.
登録日2015-07-07
公開日2015-11-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular Mechanism of CCAAT-Enhancer Binding Protein Recruitment by the TRIB1 Pseudokinase.
Structure, 23, 2015
5ULM
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BU of 5ulm by Molmil
Structure of the ASK1 central regulatory region
分子名称: GLYCEROL, Mitogen-activated protein kinase kinase kinase 5
著者Mace, P.D, Kumar, A, Caradoc-Davies, T.T.
登録日2017-01-24
公開日2017-03-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4W50
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BU of 4w50 by Molmil
Structure of the EphA4 LBD in complex with peptide
分子名称: 1,3-BUTANEDIOL, APY peptide, Ephrin type-A receptor 4, ...
著者Lechtenberg, B.C, Mace, P.D, Riedl, S.J.
登録日2014-08-16
公開日2014-10-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor.
Acs Chem.Biol., 9, 2014
4W4Z
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BU of 4w4z by Molmil
Structure of the EphA4 LBD in complex with peptide
分子名称: APY-bAla8.am peptide, Ephrin type-A receptor 4, GLYCEROL, ...
著者Lechtenberg, B.C, Mace, P.D, Riedl, S.J.
登録日2014-08-15
公開日2014-10-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor.
Acs Chem.Biol., 9, 2014
7UPM
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BU of 7upm by Molmil
Tribbles (TRIB2) pseudokinase bound to nanobody Nb4.103
分子名称: Nb4.103 Nanobody, Tribbles homolog 2
著者Jamieson, S.A, Mace, P.D.
登録日2022-04-15
公開日2022-09-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Nanobodies identify an activated state of the TRIB2 pseudokinase.
Structure, 30, 2022
6CGA
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BU of 6cga by Molmil
Structure of the PR-DUB complex
分子名称: Polycomb protein Asx, Ubiquitin carboxyl-terminal hydrolase calypso
著者Foglizzo, M, Middleton, A.J, Day, C.L, Mace, P.D.
登録日2018-02-19
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes.
Nat Commun, 9, 2018
6DC0
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BU of 6dc0 by Molmil
Tribbles (TRIB1) pseudokinase fused to CCAAT-enhancer binding protein (C/EBPalpha) degron
分子名称: Tribbles homolog 1,CCAAT/enhancer-binding protein alpha
著者Jamieson, S.A, Brewster, J.L, Mace, P.D.
登録日2018-05-03
公開日2018-10-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1.
Sci Signal, 11, 2018
5D0K
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BU of 5d0k by Molmil
Structure of UbE2D2:RNF165:Ub complex
分子名称: Polyubiquitin-B, RING finger protein 165, Ubiquitin-conjugating enzyme E2 D2, ...
著者Wright, J.D, Day, C.L, Mace, P.D.
登録日2015-08-03
公開日2015-12-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity.
Nat.Struct.Mol.Biol., 23, 2016
5D0I
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BU of 5d0i by Molmil
Structure of RING finger protein 165
分子名称: RING finger protein 165, SULFATE ION, ZINC ION
著者Wright, J.D, Day, C.L, Mace, P.D.
登録日2015-08-03
公開日2015-12-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity.
Nat.Struct.Mol.Biol., 23, 2016
5D0M
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BU of 5d0m by Molmil
Structure of UbE2D2:RNF165:Ub complex
分子名称: PHOSPHATE ION, Polyubiquitin-B, RING finger protein 165, ...
著者Wright, J.D, Day, C.L, Mace, P.D.
登録日2015-08-03
公開日2015-12-09
最終更新日2016-01-20
実験手法X-RAY DIFFRACTION (1.913 Å)
主引用文献Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity.
Nat.Struct.Mol.Biol., 23, 2016
5EDV
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BU of 5edv by Molmil
Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex
分子名称: E3 ubiquitin-protein ligase RNF31, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ...
著者Lechtenberg, B.C, Mace, P.D, Sanishvili, R, Riedl, S.J.
登録日2015-10-22
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.
Nature, 529, 2016
7R70
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BU of 7r70 by Molmil
Crystal Structure of the UbArk2C fusion protein
分子名称: GLYCEROL, Ubiquitin,E3 ubiquitin-protein ligase RNF165, ZINC ION
著者Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L.
登録日2021-06-24
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C.
Nat Commun, 13, 2022

 

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