4OUN
 
 | | Crystal Structure of Mini-ribonuclease 3 from Bacillus subtilis | | 分子名称: | Mini-ribonuclease 3 | | 著者 | Chojnowski, G, Czarnecka, J, Nowak, E, Pianka, D, Glow, D, Sabala, I, Skowronek, K, Nowotny, M, Bujnicki, J.M. | | 登録日 | 2014-02-18 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Sequence-specific cleavage of dsRNA by Mini-III RNase
Nucleic Acids Res., 43, 2015
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5V9U
 | | Crystal Structure of small molecule ARS-1620 covalently bound to K-Ras G12C | | 分子名称: | (S)-1-{4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl] piperazin-1-yl}propan-1-one, CALCIUM ION, GLYCEROL, ... | | 著者 | Janes, M.R, Zhang, J, Li, L.-S, Hansen, R, Peters, U, Guo, X, Chen, Y, Babbar, A, Firdaus, S.J, Feng, J, Chen, J.H, Li, S, Brehmer, D, Darjania, L, Li, S, Long, Y.O, Thach, C, Liu, Y, Zarieh, A, Ely, T, Kucharski, J.M, Kessler, L.V, Wu, T, Wang, Y, Yao, Y, Deng, X, Zarrinkar, P, Dashyant, D, Lorenzi, M.V, Hu-Lowe, D, Patricelli, M.P, Ren, P, Liu, Y. | | 登録日 | 2017-03-23 | | 公開日 | 2018-02-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor.
Cell, 172, 2018
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4A7J
 | | Symmetric Dimethylation of H3 Arginine 2 is a Novel Histone Mark that Supports Euchromatin Maintenance | | 分子名称: | HISTONE H3.1T, WD REPEAT-CONTAINING PROTEIN 5 | | 著者 | Migliori, V, Muller, J, Phalke, S, Low, D, Bezzi, M, ChuenMok, W, Gunaratne, J, Capasso, P, Bassi, C, Cecatiello, V, DeMarco, A, Blackstock, W, Kuznetsov, V, Amati, B, Mapelli, M, Guccione, E. | | 登録日 | 2011-11-14 | | 公開日 | 2012-01-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Symmetric Dimethylation of H3R2 is a Newly Identified Histone Mark that Supports Euchromatin Maintenance
Nat.Struct.Mol.Biol., 19, 2012
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5A4C
 | | FGFR1 ligand complex | | 分子名称: | 1,2-ETHANEDIOL, 1-tert-butyl-3-[2-[3-(diethylamino)propylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... | | 著者 | Klein, T, Vajpai, N, Phillips, J.J, Davies, G, Holdgate, G.A, Phillips, C, Tucker, J.A, Norman, R.A, Scott, A.S, Higazi, D.R, Lowe, D, Thompson, G.S, Breeze, A.L. | | 登録日 | 2015-06-05 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase.
Nat.Commun., 6, 2015
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5A46
 | | FGFR1 in complex with dovitinib | | 分子名称: | 1,2-ETHANEDIOL, 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... | | 著者 | Klein, T, Vajpai, N, Phillips, J.J, Davies, G, Holdgate, G.A, Phillips, C, Tucker, J.A, Norman, R.A, Scott, A.S, Higazi, D.R, Lowe, D, Thompson, G.S, Breeze, A.L. | | 登録日 | 2015-06-05 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase.
Nat.Commun., 6, 2015
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1A0E
 | | XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA | | 分子名称: | COBALT (II) ION, XYLOSE ISOMERASE | | 著者 | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | 登録日 | 1997-11-28 | | 公開日 | 1998-06-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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1A0D
 | | XYLOSE ISOMERASE FROM BACILLUS STEAROTHERMOPHILUS | | 分子名称: | MANGANESE (II) ION, XYLOSE ISOMERASE | | 著者 | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | 登録日 | 1997-11-28 | | 公開日 | 1998-06-03 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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1A0C
 | | XYLOSE ISOMERASE FROM THERMOANAEROBACTERIUM THERMOSULFURIGENES | | 分子名称: | COBALT (II) ION, XYLOSE ISOMERASE | | 著者 | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | 登録日 | 1997-11-28 | | 公開日 | 1998-06-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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7LMX
 | | A HIGHLY SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 WITH A DISULFIDE | | 分子名称: | Integrin inhibitor | | 著者 | Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D. | | 登録日 | 2021-02-06 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
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7LMV
 | | SPECIFIC INHIBITOR OF INTEGRIN ALPHA-V BETA-6 | | 分子名称: | Integrin inhibitor | | 著者 | Dong, X, Bera, A.K, Roy, A, Shi, L, Springer, T.A, Baker, D. | | 登録日 | 2021-02-05 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
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4ZPE
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4ZPF
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4ZPG
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8TCF
 | | Integrin alpha-v beta-8 in complex with minibinder B8_BP_dsulf | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. | | 登録日 | 2023-06-30 | | 公開日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
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8TCG
 | | Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V heavy chain, ... | | 著者 | Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. | | 登録日 | 2023-06-30 | | 公開日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
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5J4Y
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5J4V
 | | The crystal structure of Inhibitor Bound to JCV Helicase | | 分子名称: | 2-(2-phenoxypyridin-3-yl)[1,3]thiazolo[5,4-c]pyridine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Large T antigen, ... | | 著者 | Ter Haar, E. | | 登録日 | 2016-04-01 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Fragment-Based Discovery of Dual JC Virus and BK Virus Helicase Inhibitors.
J.Med.Chem., 59, 2016
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5J47
 | | The X-ray structure of Inhibitor Bound to JCV Helicase | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-phenoxyphenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole, Large T antigen, ... | | 著者 | Ter Haar, E. | | 登録日 | 2016-03-31 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Fragment-Based Discovery of Dual JC Virus and BK Virus Helicase Inhibitors.
J.Med.Chem., 59, 2016
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5J40
 | | The X-ray structure of JCV Helicase | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Large T antigen, SULFATE ION, ... | | 著者 | Ter Haar, E. | | 登録日 | 2016-03-31 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Fragment-Based Discovery of Dual JC Virus and BK Virus Helicase Inhibitors.
J.Med.Chem., 59, 2016
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5JZ7
 | | NGF IN COMPLEX WITH MEDI578 scFv | | 分子名称: | Beta-nerve growth factor, MEDI578 scFv, heavy chain, ... | | 著者 | Olsson, L.-L, Aagaard, A. | | 登録日 | 2016-05-16 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.
Sci Rep, 6, 2016
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6BFT
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6BGT
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194L
 | | THE 1.40 A STRUCTURE OF SPACEHAB-01 HEN EGG WHITE LYSOZYME | | 分子名称: | CHLORIDE ION, LYSOZYME, SODIUM ION | | 著者 | Vaney, M.C, Maignan, S, Ries-Kautt, M, Ducruix, A. | | 登録日 | 1995-09-01 | | 公開日 | 1995-12-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | High-resolution structure (1.33 A) of a HEW lysozyme tetragonal crystal grown in the APCF apparatus. Data and structural comparison with a crystal grown under microgravity from SpaceHab-01 mission.
Acta Crystallogr.,Sect.D, 52, 1996
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193L
 | | THE 1.33 A STRUCTURE OF TETRAGONAL HEN EGG WHITE LYSOZYME | | 分子名称: | CHLORIDE ION, LYSOZYME, SODIUM ION | | 著者 | Vaney, M.C, Maignan, S, Ries-Kautt, M, Ducruix, A. | | 登録日 | 1995-09-01 | | 公開日 | 1995-12-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | High-resolution structure (1.33 A) of a HEW lysozyme tetragonal crystal grown in the APCF apparatus. Data and structural comparison with a crystal grown under microgravity from SpaceHab-01 mission.
Acta Crystallogr.,Sect.D, 52, 1996
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8QFY
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