8WVB
| Crystal structure of Lsd18 mutant S195M | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Putative epoxidase LasC | 著者 | Liu, N, Xiao, H.L, Chen, X. | 登録日 | 2023-10-23 | 公開日 | 2023-12-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Simultaneous Improvement in the Thermostability and Catalytic Activity of Epoxidase Lsd18 for the Synthesis of Lasalocid A. Int J Mol Sci, 24, 2023
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8WVF
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8IPG
| Structure of HP101/N44 | 分子名称: | Env polyprotein (Fragment), HP101 | 著者 | Liu, N, Qin, B. | 登録日 | 2023-03-14 | 公開日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Structure of HP101/N44 To Be Published
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7DL3
| The structure of 3,5-DAHDHcca complex with NADPH | 分子名称: | 3,5-diaminohexanoate dehydrogenase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | 登録日 | 2020-11-25 | 公開日 | 2021-09-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.84606934 Å) | 主引用文献 | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DL0
| The mutant E310G/A314Y of 3,5-DAHDHcca complex with NADPH | 分子名称: | 1,2-ETHANEDIOL, 3,5-diaminohexanoate dehydrogenase, CHLORIDE ION, ... | 著者 | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | 登録日 | 2020-11-25 | 公開日 | 2021-09-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DL7
| The wild-type structure of 3,5-DAHDHcca | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,5-diaminohexanoate dehydrogenase, ... | 著者 | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | 登録日 | 2020-11-26 | 公開日 | 2021-09-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.30065823 Å) | 主引用文献 | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7DL1
| The mutant E310G/G323S structure of 3,5-DAHDHcca complex with NADPH | 分子名称: | 3,5-diaminohexanoate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Liu, N, Wu, L, Zhu, D.M, Zhou, J.H. | 登録日 | 2020-11-25 | 公開日 | 2021-09-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of beta-Amino Acids. Angew.Chem.Int.Ed.Engl., 60, 2021
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7D0F
| cryo-EM structure of a pre-catalytic group II intron RNP | 分子名称: | Group II intron-encoded protein LtrA, RNA (738-MER) | 著者 | Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M. | 登録日 | 2020-09-10 | 公開日 | 2020-09-30 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing. Nucleic Acids Res., 48, 2020
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7D0G
| Cryo-EM structure of a pre-catalytic group II intron | 分子名称: | Group II intron-encoded protein LtrA, RNA (714-MER) | 著者 | Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M. | 登録日 | 2020-09-10 | 公開日 | 2020-09-30 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing. Nucleic Acids Res., 48, 2020
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7D1A
| cryo-EM structure of a group II intron RNP complexed with its reverse transcriptase | 分子名称: | Group II intron-encoded protein LtrA, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3'), RNA (692-MER) | 著者 | Liu, N, Dong, X.L, Hu, C.X, Zeng, J.W, Wang, J.W, Wang, J, Wang, H.W, Belfort, M. | 登録日 | 2020-09-14 | 公開日 | 2020-10-21 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing. Nucleic Acids Res., 48, 2020
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8GVK
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8H2H
| Cryo-EM structure of a Group II Intron Complexed with its Reverse Transcriptase | 分子名称: | Group II intron-encoded protein LtrA, LtrB, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3') | 著者 | Liu, N, Dong, X.L, Qu, G.S, Wang, J, Wang, H.W, Belfort, M. | 登録日 | 2022-10-06 | 公開日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Functionalized graphene grids with various charges for single-particle cryo-EM. Nat Commun, 13, 2022
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7EG0
| Cryo-EM structure of anagrelide-induced PDE3A-SLFN12 complex | 分子名称: | 6,7-bis(chloranyl)-3,5-dihydro-1H-imidazo[2,1-b]quinazolin-2-one, MAGNESIUM ION, Schlafen family member 12, ... | 著者 | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | 登録日 | 2021-03-23 | 公開日 | 2021-09-29 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nat Commun, 12, 2021
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7EG4
| Cryo-EM structure of nauclefine-induced PDE3A-SLFN12 complex | 分子名称: | MAGNESIUM ION, Parvine, Schlafen family member 12, ... | 著者 | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | 登録日 | 2021-03-24 | 公開日 | 2021-09-29 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nat Commun, 12, 2021
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7EG1
| Cryo-EM structure of DNMDP-induced PDE3A-SLFN12 complex | 分子名称: | (4~{R})-3-[4-(diethylamino)-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]-4-methyl-4,5-dihydro-1~{H}-pyridazin-6-one, MAGNESIUM ION, Schlafen family member 12, ... | 著者 | Liu, N, Chen, J, Wang, X.D, Wang, H.W. | 登録日 | 2021-03-23 | 公開日 | 2021-11-03 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nat Commun, 12, 2021
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7YIM
| Cryo-EM structure of human Alpha-fetoprotein | 分子名称: | Alpha-fetoprotein | 著者 | Liu, N, Liu, K, Wu, C, Liu, Z, Li, M, Wang, J, Wang, H.W. | 登録日 | 2022-07-17 | 公開日 | 2023-01-18 | 最終更新日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM. Nat.Methods, 20, 2023
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7XGY
| cryo-EM structure of hemoglobin | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Liu, N, Wang, H.W. | 登録日 | 2022-04-07 | 公開日 | 2022-11-09 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM. Nat.Methods, 20, 2023
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8HRJ
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8HRL
| SARS-CoV-2 Delta S-RBD-ACE2 | 分子名称: | Processed angiotensin-converting enzyme 2, Spike protein S1 | 著者 | Xu, J, Meng, F, Liu, N, Wang, H.W. | 登録日 | 2022-12-15 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Self-assembled monolayers guided free-standing atomic-crystal/molecule superstructure To Be Published
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8HRK
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8HRN
| Cryo-EM structure of ACE2 | 分子名称: | Angiotensin-converting enzyme 2 | 著者 | Xu, J, Liu, N, Wang, H.W. | 登録日 | 2022-12-15 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Self-assembled monolayers guided free-standing atomic-crystal/molecule superstructure To Be Published
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8HRU
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8HRI
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8HRM
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1C94
| REVERSING THE SEQUENCE OF THE GCN4 LEUCINE ZIPPER DOES NOT AFFECT ITS FOLD. | 分子名称: | RETRO-GCN4 LEUCINE ZIPPER | 著者 | Mittl, P.R.E, Deillon, C.A, Sargent, D, Liu, N, Klauser, S, Thomas, R.M, Gutte, B, Gruetter, M.G. | 登録日 | 1999-07-30 | 公開日 | 2000-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | The retro-GCN4 leucine zipper sequence forms a stable three-dimensional structure. Proc.Natl.Acad.Sci.USA, 97, 2000
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