4UX5
| Structure of DNA complex of PCG2 | 分子名称: | 5'-D(*CP*AP*AP*TP*GP*AP*CP*GP*CP*GP*TP*AP*AP*GP)-3', 5'-D(*CP*TP*TP*AP*CP*GP*CP*GP*TP*CP*AP*TP*TP*GP)-3', TRANSCRIPTION FACTOR MBP1 | 著者 | Liu, J, Huang, J, Zhao, Y, Liu, H, Wang, D, Yang, J, Zhao, W, Taylor, I.A, Peng, Y. | 登録日 | 2014-08-19 | 公開日 | 2015-01-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Basis of DNA Recognition by Pcg2 Reveals a Novel DNA Binding Mode for Winged Helix-Turn-Helix Domains. Nucleic Acids Res., 43, 2015
|
|
6ZVS
| C12 symmetry: Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily. | 分子名称: | Vipp1 | 著者 | Liu, J, Tassinari, M, Souza, D.P, Naskar, S, Noel, J.K, Bohuszewicz, O, Buck, M, Williams, T.A, Baum, B, Low, H.H. | 登録日 | 2020-07-27 | 公開日 | 2021-08-04 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily. Cell, 184, 2021
|
|
6ZW6
| C16 symmetry: Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily. | 分子名称: | vipp1 | 著者 | Liu, J, Tassinari, M, Souza, D.P, Naskar, S, Noel, J.K, Bohuszewicz, O, Buck, M, Williams, T.A, Baum, B, Low, H.H. | 登録日 | 2020-07-27 | 公開日 | 2021-08-04 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | 主引用文献 | Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily. Cell, 184, 2021
|
|
6ZW7
| C17 symmetry: Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily. | 分子名称: | vipp1 | 著者 | Liu, J, Tassinari, M, Souza, D.P, Naskar, S, Noel, J.K, Bohuszewicz, O, Buck, M, Williams, T.A, Baum, B, Low, H.H. | 登録日 | 2020-07-27 | 公開日 | 2021-08-04 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | 主引用文献 | Bacterial Vipp1 and PspA are members of the ancient ESCRT-III membrane-remodeling superfamily. Cell, 184, 2021
|
|
8HOG
| Crystal structure of Bcl-2 in complex with sonrotoclax | 分子名称: | Apoptosis regulator Bcl-2, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide | 著者 | Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y. | 登録日 | 2022-12-10 | 公開日 | 2024-01-17 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy. Blood, 143, 2024
|
|
8HOH
| Crystal structure of Bcl-2 G101V in complex with sonrotoclax | 分子名称: | Apoptosis regulator Bcl-2, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide | 著者 | Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y. | 登録日 | 2022-12-10 | 公開日 | 2024-01-17 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy. Blood, 143, 2024
|
|
8HOI
| Crystal structure of Bcl-2 D103Y in complex with sonrotoclax | 分子名称: | Apoptosis regulator Bcl-2, FORMIC ACID, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide | 著者 | Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y. | 登録日 | 2022-12-10 | 公開日 | 2024-01-17 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy. Blood, 143, 2024
|
|
6U3F
| Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | Panton-Valentine Leucocidin F, SULFATE ION, fos-choline-14 | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-21 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|
6U2S
| Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | Bi-component leukocidin LukED subunit D, fos-choline-14 | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-20 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|
6U33
| Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | Bi-component leukocidin LukED subunit D, NICKEL (II) ION | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-21 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|
6U3T
| Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | Alpha-hemolysin, SULFATE ION, fos-choline-14 | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-22 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|
6U4P
| Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | Alpha-hemolysin, SULFATE ION, fos-choline-14 | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-26 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|
1F23
| CONTRIBUTION OF A BURIED HYDROGEN BOND TO HIV-1 ENVELOPE GLYCOPROTEIN STRUCTURE AND FUNCTION | 分子名称: | TRANSMEMBRANE GLYCOPROTEIN | 著者 | Liu, J, Shu, W, Fagan, M, Nunberg, J.H, Lu, M. | 登録日 | 2000-05-23 | 公開日 | 2001-06-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and functional analysis of the HIV gp41 core containing an Ile573 to Thr substitution: implications for membrane fusion. Biochemistry, 40, 2001
|
|
1FNN
| CRYSTAL STRUCTURE OF CDC6P FROM PYROBACULUM AEROPHILUM | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CELL DIVISION CONTROL PROTEIN 6, MAGNESIUM ION | 著者 | Liu, J, Smith, C.L, DeRyckere, D, DeAngelis, K, Martin, G.S, Berger, J.M. | 登録日 | 2000-08-22 | 公開日 | 2000-10-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control. Mol.Cell, 6, 2000
|
|
5YJ8
| |
2FRW
| |
2FRY
| |
2WR0
| Structures of influenza H2 Hemagglutinins | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, ... | 著者 | Liu, J, Stevens, D, Haire, L, Coombs, P, Russell, R, Gamblin, S, Skehel, J. | 登録日 | 2009-08-28 | 公開日 | 2009-09-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3C2G
| Crystal complex of SYS-1/POP-1 at 2.5A resolution | 分子名称: | Pop-1 8-residue peptide, Sys-1 protein | 著者 | Liu, J, Phillips, B.T, Amaya, M.F, Kimble, J, Xu, W. | 登録日 | 2008-01-24 | 公開日 | 2008-05-20 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The C. elegans SYS-1 protein is a bona fide beta-catenin. Dev.Cell, 14, 2008
|
|
3C2H
| Crystal Structure of SYS-1 at 2.6A resolution | 分子名称: | CITRATE ANION, GLYCEROL, Sys-1 protein | 著者 | Liu, J, Phillips, B.T, Amaya, M.F, Kimble, J, Xu, W. | 登録日 | 2008-01-25 | 公開日 | 2008-05-20 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The C. elegans SYS-1 protein is a bona fide beta-catenin. Dev.Cell, 14, 2008
|
|
1JCC
| Crystal Structure of a Novel Alanine-Zipper Trimer at 1.7 A Resolution, V13A,L16A,V20A,L23A,V27A,M30A,V34A mutations | 分子名称: | MAJOR OUTER MEMBRANE LIPOPROTEIN, ZINC ION | 著者 | Liu, J, Dai, J, Lu, M. | 登録日 | 2001-06-08 | 公開日 | 2003-06-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Zinc-Mediated Helix Capping in A Triple-Helical Protein Biochemistry, 42, 2003
|
|
8E7X
| RsTSPO A138F with one Heme bound | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, Tryptophan-rich sensory protein | 著者 | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | 登録日 | 2022-08-25 | 公開日 | 2023-03-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
|
|
8E7Z
| RsTSPO mutant -A138F | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Tryptophan-rich sensory protein | 著者 | Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S. | 登録日 | 2022-08-25 | 公開日 | 2023-03-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity. Biochemistry, 62, 2023
|
|
6U49
| Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | Alpha-hemolysin, SULFATE ION, fos-choline-14 | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-23 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|
6U3Y
| Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | ACETATE ION, Gamma-hemolysin subunit A, Panton-Valentine Leucocidin F, ... | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-22 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|