8K4M
 
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1NY5
 | | Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Lee, S.Y, de la Torre, A, Kustu, S, Nixon, B.T, Wemmer, D.E. | | 登録日 | 2003-02-11 | | 公開日 | 2003-11-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Regulation of the transcriptional activator NtrC1: structural studies of the regulatory and AAA+ ATPase domains
Genes Dev., 17, 2003
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1NY6
 | | Crystal structure of sigm54 activator (AAA+ ATPase) in the active state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, transcriptional regulator (NtrC family) | | 著者 | Lee, S.Y, de la Torre, A, Kustu, S, Nixon, B.T, Wemmer, D.E. | | 登録日 | 2003-02-11 | | 公開日 | 2003-11-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Regulation of the transcriptional activator NtrC1: structural studies of the regulatory and AAA+ ATPase domains
Genes Dev., 17, 2003
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2A0L
 | | Crystal structure of KvAP-33H1 Fv complex | | 分子名称: | 33H1 Fv fragment, POTASSIUM ION, Voltage-gated potassium channel | | 著者 | Lee, S.Y, Lee, A, Chen, J, Mackinnon, R. | | 登録日 | 2005-06-16 | | 公開日 | 2005-11-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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1F4V
 | | CRYSTAL STRUCTURE OF ACTIVATED CHEY BOUND TO THE N-TERMINUS OF FLIM | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, CHEMOTAXIS CHEY PROTEIN, FLAGELLAR MOTOR SWITCH PROTEIN, ... | | 著者 | Lee, S.Y, Cho, H.S, Pelton, J.G, Yan, D, Henderson, R.K, King, D, Huang, L.S, Kustu, S, Berry, E.A, Wemmer, D.E. | | 登録日 | 2000-06-10 | | 公開日 | 2001-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Crystal structure of an activated response regulator bound to its target.
Nat.Struct.Biol., 8, 2001
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1FQW
 | | CRYSTAL STRUCTURE OF ACTIVATED CHEY | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, CHEMOTAXIS CHEY PROTEIN, MANGANESE (II) ION | | 著者 | Lee, S.Y, Cho, H.S, Pelton, J.G, Yan, D, Berry, E.A, Wemmer, D.E. | | 登録日 | 2000-09-07 | | 公開日 | 2001-07-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Crystal structure of activated CheY. Comparison with other activated receiver domains.
J.Biol.Chem., 276, 2001
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7V6E
 | | DREP3 | | 分子名称: | DNAation factor-related protein 3, isoform A | | 著者 | Lee, S.Y, Park, H.H. | | 登録日 | 2021-08-20 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Helical filament structure of the DREP3 CIDE domain reveals a unified mechanism of CIDE-domain assembly.
Acta Crystallogr D Struct Biol, 77, 2021
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7VI8
 | | Crystal structure of ChbG | | 分子名称: | ACETATE ION, Chitooligosaccharide deacetylase, ZINC ION | | 著者 | Lee, S.Y, Park, H.H. | | 登録日 | 2021-09-26 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystal structure of ChbG from Klebsiella pneumoniae reveals the molecular basis of diacetylchitobiose deacetylation.
Commun Biol, 5, 2022
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7XI5
 | | Anti-CRISPR-associated Aca10 | | 分子名称: | Transcriptional regulator | | 著者 | Lee, S.Y, Park, H.H. | | 登録日 | 2022-04-12 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Molecular basis of anti-CRISPR operon repression by Aca10.
Nucleic Acids Res., 50, 2022
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7CHQ
 | | AcrIE2 | | 分子名称: | anti-CRISPR AcrIE2 | | 著者 | Lee, S.Y, Park, H.H. | | 登録日 | 2020-07-06 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | A 1.3 angstrom high-resolution crystal structure of an anti-CRISPR protein, AcrI E2.
Biochem.Biophys.Res.Commun., 533, 2020
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7EZY
 | | anti-CRISPR-associated Aca2 | | 分子名称: | anti-CRISPR-associated Aca2 | | 著者 | Lee, S.Y, Park, H.H. | | 登録日 | 2021-06-02 | | 公開日 | 2022-01-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Molecular basis of transcriptional repression ofanti-CRISPR by anti-CRISPR-associated 2
Acta Crystallogr.,Sect.D, 78, 2022
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5GPG
 | | Co-crystal structure of the FK506 binding domain of human FKBP25, Rapamycin and the FRB domain of human mTOR | | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP3, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, Serine/threonine-protein kinase mTOR | | 著者 | Lee, H.B, Lee, S.Y, Rhee, H.W, Lee, C.W. | | 登録日 | 2016-08-02 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Proximity-Directed Labeling Reveals a New Rapamycin-Induced Heterodimer of FKBP25 and FRB in Live Cells
Acs Cent.Sci., 2, 2016
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5CKR
 | | Crystal Structure of MraY in complex with Muraymycin D2 | | 分子名称: | Muraymycin D2, Phospho-N-acetylmuramoyl-pentapeptide-transferase | | 著者 | Lee, S.Y, Chung, B.C, Mashalidis, E.H, Tanino, T, Kim, M, Hong, J, Ichikawa, S. | | 登録日 | 2015-07-15 | | 公開日 | 2016-03-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural insights into inhibition of lipid I production in bacterial cell wall synthesis.
Nature, 533, 2016
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4J72
 | | Crystal Structure of polyprenyl-phosphate N-acetyl hexosamine 1-phosphate transferase | | 分子名称: | MAGNESIUM ION, NICKEL (II) ION, Phospho-N-acetylmuramoyl-pentapeptide-transferase | | 著者 | Lee, S.Y, Chung, B.C, Gillespie, R.A, Kwon, D.Y, Guan, Z, Zhou, P, Hong, J. | | 登録日 | 2013-02-12 | | 公開日 | 2013-09-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis.
Science, 341, 2013
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1DJM
 | | SOLUTION STRUCTURE OF BEF3-ACTIVATED CHEY FROM ESCHERICHIA COLI | | 分子名称: | CHEMOTAXIS PROTEIN Y | | 著者 | Cho, H.S, Lee, S.Y, Yan, D, Pan, X, Parkinson, J.S, Kustu, S, Wemmer, D.E, Pelton, J.G. | | 登録日 | 1999-12-03 | | 公開日 | 2000-04-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of activated CheY.
J.Mol.Biol., 297, 2000
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4DCK
 | | Crystal structure of the C-terminus of voltage-gated sodium channel in complex with FGF13 and CaM | | 分子名称: | Calmodulin, Fibroblast growth factor 13, MAGNESIUM ION, ... | | 著者 | Chung, B.C, Wang, C, Yan, H, Pitt, G.S, Lee, S.Y. | | 登録日 | 2012-01-17 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of the Ternary Complex of a NaV C-Terminal Domain, a Fibroblast Growth Factor Homologous Factor, and Calmodulin.
Structure, 20, 2012
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6OYZ
 | | Crystal structure of MraY bound to capuramycin | | 分子名称: | (2~{S},3~{S},4~{S})-2-[(1~{R})-2-azanyl-1-[(2~{S},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-methoxy-4-oxidanyl-oxolan-2-yl]-2-oxidanylidene-ethoxy]-3,4-bis(oxidanyl)-~{N}-[(3~{S})-2-oxidanylideneazepan-3-yl]-3,4-dihydro-2~{H}-pyran-6-carboxamide, MraYAA nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase | | 著者 | Mashalidis, E.H, Lee, S.Y. | | 登録日 | 2019-05-15 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.62 Å) | | 主引用文献 | Chemical logic of MraY inhibition by antibacterial nucleoside natural products.
Nat Commun, 10, 2019
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6OYH
 | | Crystal structure of MraY bound to carbacaprazamycin | | 分子名称: | (5S)-5'-O-(5-amino-5-deoxy-beta-D-ribofuranosyl)-5'-C-[(2S,5S,6S)-5-carboxy-6-heptadecyl-1,4-dimethyl-3-oxo-1,4-diazepan-2-yl]uridine, MraYAA nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase | | 著者 | Mashalidis, E.H, Lee, S.Y. | | 登録日 | 2019-05-14 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Chemical logic of MraY inhibition by antibacterial nucleoside natural products.
Nat Commun, 10, 2019
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6OZ6
 | | Crystal structure of MraY bound to 3'-hydroxymureidomycin A | | 分子名称: | (2~{S})-2-[[(2~{S})-1-[[(2~{S},3~{S})-3-[[(2~{S})-2-azanyl-3-(3-hydroxyphenyl)propanoyl]-methyl-amino]-1-[[(~{Z})-[(3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-ylidene]methyl]amino]-1-oxidanylidene-butan-2-yl]amino]-4-methylsulfanyl-1-oxidanylidene-butan-2-yl]carbamoylamino]-3-(3-hydroxyphenyl)propanoic acid, MraYAA nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase | | 著者 | Mashalidis, E.H, Lee, S.Y. | | 登録日 | 2019-05-15 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Chemical logic of MraY inhibition by antibacterial nucleoside natural products.
Nat Commun, 10, 2019
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1ZDR
 | | DHFR from Bacillus Stearothermophilus | | 分子名称: | GLYCEROL, SULFATE ION, dihydrofolate reductase | | 著者 | Kim, H.S, Damo, S.M, Lee, S.Y, Wemmer, D, Klinman, J.P. | | 登録日 | 2005-04-14 | | 公開日 | 2005-08-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and hydride transfer mechanism of a moderate thermophilic dihydrofolate reductase from Bacillus stearothermophilus and comparison to its mesophilic and hyperthermophilic homologues.
Biochemistry, 44, 2005
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4HNZ
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4HO7
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1PUX
 | | NMR Solution Structure of BeF3-Activated Spo0F, 20 conformers | | 分子名称: | Sporulation initiation phosphotransferase F | | 著者 | Gardino, A.K, Volkman, B.F, Cho, H.S, Lee, S.Y, Wemmer, D.E, Kern, D. | | 登録日 | 2003-06-25 | | 公開日 | 2003-08-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system.
J.Mol.Biol., 331, 2003
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1RLO
 | | Phospho-aspartyl Intermediate Analogue of ybiV from E. coli K12 | | 分子名称: | GLYCEROL, MAGNESIUM ION, Phosphatase | | 著者 | Roberts, A, Lee, S.Y, McCullagh, E, Silversmith, R.E, Wemmer, D.E. | | 登録日 | 2003-11-26 | | 公開日 | 2004-12-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Ybiv from Escherichia coli K12 is a HAD phosphatase.
Proteins, 58, 2005
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1PXH
 | | Crystal structure of protein tyrosine phosphatase 1B with potent and selective bidentate inhibitor compound 2 | | 分子名称: | ACETIC ACID, MAGNESIUM ION, N-{1-[5-(1-CARBAMOYL-2-MERCAPTO-ETHYLCARBAMOYL)-PENTYLCARBAMOYL]-2-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-ETHYL}-3-{2-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-ACETYLAMINO}-SUCCINAMIC ACID, ... | | 著者 | Sun, J.P, Fedorov, A, Lee, S.Y, Guo, X.L, Shen, K, Lawrence, D.S, Almo, S.C, Zhang, Z.Y. | | 登録日 | 2003-07-04 | | 公開日 | 2003-08-12 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor.
J.Biol.Chem., 278, 2003
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