7AA9
 
 | | Structure of SCOC pT13/pT15 LIR motif bound to GABARAPL1 | | 分子名称: | Gamma-aminobutyric acid receptor-associated protein-like 1, pT13/PT15 SCOC LIR | | 著者 | Lee, R, Mouilleron, S, Wirth, M, Zhang, W, O Reilly, N, Dhira, J, Tooze, S. | | 登録日 | 2020-09-03 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
J.Mol.Biol., 433, 2021
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7AA8
 | | Structure of SCOC LIR bound to GABARAP | | 分子名称: | Chimera made of SCOC (6-23) + linker (GS) + GABARAP,Gamma-aminobutyric acid receptor-associated protein | | 著者 | Lee, R, Mouilleron, S, Wirth, M, Zhang, W, O Reilly, N, Dhira, J, Tooze, S. | | 登録日 | 2020-09-03 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
J.Mol.Biol., 433, 2021
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7AA7
 | | Structure of SCOC pS12/pS18 LIR motif bound to GABARAPL1 | | 分子名称: | Gamma-aminobutyric acid receptor-associated protein-like 1, pS12/pS18 SCOC LIR, sulfoacetic acid | | 著者 | Lee, R, Mouilleron, S, Wirth, M, Zhang, W, O Reilly, N, Dhira, J, Tooze, S. | | 登録日 | 2020-09-03 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.
J.Mol.Biol., 433, 2021
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6ZEJ
 | | Structure of PP1-Phactr1 chimera [PP1(7-304) + linker (SGSGS) + Phactr1(526-580)] | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M. | | 登録日 | 2020-06-16 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Elife, 9, 2020
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6ZEH
 | | Structure of PP1-spectrin alpha II chimera [PP1(7-304) + linker (G/S)x9 + spectrin alpha II (1025-1039)] bound to Phactr1 (516-580) | | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, Phosphatase and actin regulator, ... | | 著者 | Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M. | | 登録日 | 2020-06-16 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Elife, 9, 2020
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6ZEI
 | | Structure of PP1-IRSp53 S455E chimera [PP1(7-304) + linker (G/S)x9 + IRSp53(449-465)] bound to Phactr1 (516-580) | | 分子名称: | GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ... | | 著者 | Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M. | | 登録日 | 2020-06-16 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Elife, 9, 2020
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6ZEG
 | | Structure of PP1-IRSp53 chimera [PP1(7-304) + linker (G/S)x9 + IRSp53(449-465)] bound to Phactr1 (516-580) | | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE, MANGANESE (II) ION, ... | | 著者 | Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M. | | 登録日 | 2020-06-16 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Elife, 9, 2020
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6ZEE
 | | Structure of PP1(7-300) bound to Phactr1 (507-580) at pH8.4 | | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE, GLYCEROL, ... | | 著者 | Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M. | | 登録日 | 2020-06-16 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Elife, 9, 2020
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6ZEF
 | | Structure of PP1(7-300) bound to Phactr1 (516-580) at pH 5.25 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MANGANESE (II) ION, ... | | 著者 | Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M. | | 登録日 | 2020-06-16 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Elife, 9, 2020
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5LXH
 | | GABARAP-L1 ATG4B LIR Complex | | 分子名称: | Cysteine protease ATG4B, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein-like 1, ... | | 著者 | Mouilleron, S, Skytte Rasmussen, M, Kumar Shrestha, B, Wirth, M, Bowitz Larsen, K, Abudu Princely, Y, Sjottem, E, Tooze, S, Lamark, T, Johansen, T, Lee, R. | | 登録日 | 2016-09-21 | | 公開日 | 2017-02-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Autophagy, 13, 2017
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5LXI
 | | GABARAP-L1 ATG4B LIR Complex | | 分子名称: | 1,2-ETHANEDIOL, Cysteine protease ATG4B, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Mouilleron, S, Skytte Rasmussen, M, Kumar Shrestha, B, Wirth, M, Bowitz Larsen, K, Abudu Princely, Y, Sjottem, E, Tooze, S, Lamark, T, Johansen, T, Lee, R. | | 登録日 | 2016-09-21 | | 公開日 | 2017-02-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Autophagy, 13, 2017
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8TXA
 | | Apo Structure of (N1G37) tRNA Methyltransferase from Mycobacterium marinum | | 分子名称: | tRNA (guanine-N(1)-)-methyltransferase | | 著者 | Balsamo, A, Bruno, C, Edele, C, Fabian, T, Jannotta, R, Lee, R, Schryver, D, Warsaw, J, Warsaw, L, Stojanoff, V, Battaile, K, Perez, A, Bolen, R. | | 登録日 | 2023-08-23 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.591 Å) | | 主引用文献 | Apo Structure of (N1G37) tRNA Methyltransferase from Mycobacterium marinum
To Be Published
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6HOL
 | | Structure of ATG14 LIR motif bound to GABARAPL1 | | 分子名称: | Beclin 1-associated autophagy-related key regulator, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein-like 1, ... | | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
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6HOJ
 | | Structure of Beclin1 LIR motif bound to GABARAP | | 分子名称: | 1,2-ETHANEDIOL, Beclin-1,Gamma-aminobutyric acid receptor-associated protein, SULFATE ION | | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
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6HOH
 | | Structure of VPS34 LIR motif (S249E) bound to GABARAP | | 分子名称: | Phosphatidylinositol 3-kinase catalytic subunit type 3,Gamma-aminobutyric acid receptor-associated protein, TRIETHYLENE GLYCOL | | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
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6HOI
 | | Structure of Beclin1 LIR motif bound to GABARAPL1 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Beclin-1, ... | | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
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6HOK
 | | Structure of Beclin1 LIR (S96E) motif bound to GABARAP | | 分子名称: | 1,2-ETHANEDIOL, Beclin-1,Gamma-aminobutyric acid receptor-associated protein | | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
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6HOG
 | | Structure of VPS34 LIR motif bound to GABARAP | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3,Gamma-aminobutyric acid receptor-associated protein, ... | | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
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2LH8
 | | Syrian hamster prion protein with thiamine | | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Major prion protein | | 著者 | Perez-Pineiro, R, Bjorndahl, T.C, Berjanskii, M, Hau, D, Li, L, Huang, A, Lee, R, Gibbs, E, Ladner, C, Wei Dong, Y, Abera, A, Cashman, N.R, Wishart, D. | | 登録日 | 2011-08-05 | | 公開日 | 2011-09-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The prion protein binds thiamine.
Febs J., 278, 2011
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7K6Q
 | | Active state Dot1 bound to the H4K16ac nucleosome | | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J. | | 登録日 | 2020-09-21 | | 公開日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
Science, 371, 2021
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7K6P
 | | Active state Dot1 bound to the unacetylated H4 nucleosome | | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J. | | 登録日 | 2020-09-21 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
Science, 371, 2021
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6L3A
 | | Cytochrome P450 107G1 (RapN) with everolimus | | 分子名称: | Cytochrome P450, Everolimus, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Km, V.C, Kim, D.H, Lim, Y.R, Lee, I.H, Lee, J.H, Kang, L.W. | | 登録日 | 2019-10-10 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus.
Arch.Biochem.Biophys., 692, 2020
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6L39
 | | Cytochrome P450 107G1 (RapN) | | 分子名称: | Cytochrome P450, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | | 著者 | Kim, V.C, Kim, D.H, Lim, Y.R, Lee, I.H, Lee, J.H, Kang, L.W. | | 登録日 | 2019-10-10 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Structural insights into CYP107G1 from rapamycin-producing Streptomyces rapamycinicus.
Arch.Biochem.Biophys., 692, 2020
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6GQF
 | | The structure of mouse AsterA (GramD1a) with 25-hydroxy cholesterol | | 分子名称: | 25-HYDROXYCHOLESTEROL, GLYCEROL, GRAM domain-containing protein 1A | | 著者 | Fairall, L, Gurnett, J.E, Vashi, D, Sandhu, J, Tontonoz, P, Schwabe, J.W.R. | | 登録日 | 2018-06-07 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells.
Cell, 175, 2018
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6GHM
 | | Structure of PP1 alpha phosphatase bound to ASPP2 | | 分子名称: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Apoptosis-stimulating of p53 protein 2, ... | | 著者 | Mouilleron, S, Bertran, T.M, Tapon, N, Zhou, Y. | | 登録日 | 2018-05-08 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail.
Nat Commun, 10, 2019
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