6GQF
The structure of mouse AsterA (GramD1a) with 25-hydroxy cholesterol
Summary for 6GQF
Entry DOI | 10.2210/pdb6gqf/pdb |
Descriptor | GRAM domain-containing protein 1A, 25-HYDROXYCHOLESTEROL, GLYCEROL (3 entities in total) |
Functional Keywords | cholesterol, plasma membrane, endoplasmic reticulum, lipid transport |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 4 |
Total formula weight | 105960.82 |
Authors | Fairall, L.,Gurnett, J.E.,Vashi, D.,Sandhu, J.,Tontonoz, P.,Schwabe, J.W.R. (deposition date: 2018-06-07, release date: 2018-09-26, Last modification date: 2024-01-17) |
Primary citation | Sandhu, J.,Li, S.,Fairall, L.,Pfisterer, S.G.,Gurnett, J.E.,Xiao, X.,Weston, T.A.,Vashi, D.,Ferrari, A.,Orozco, J.L.,Hartman, C.L.,Strugatsky, D.,Lee, S.D.,He, C.,Hong, C.,Jiang, H.,Bentolila, L.A.,Gatta, A.T.,Levine, T.P.,Ferng, A.,Lee, R.,Ford, D.A.,Young, S.G.,Ikonen, E.,Schwabe, J.W.R.,Tontonoz, P. Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells. Cell, 175:514-529.e20, 2018 Cited by PubMed: 30220461DOI: 10.1016/j.cell.2018.08.033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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