6HOK

Structure of Beclin1 LIR (S96E) motif bound to GABARAP

Summary for 6HOK

• Entry DOI: 10.2210/pdb6hok/pdb
• Descriptor: Beclin-1,Gamma-aminobutyric acid receptor-associated protein, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: autophagy, atg8, lir, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 15026.10

Authors

Mouilleron, S.,Birgisdottir, A.B.,Bhujbal, Z.,Wirth, M.,Sjottem, E.,Evjen, G.,Zhang, W.,Lee, R.,O'Reilly, N.,Tooze, S.,Lamark, T.,Johansen, T. (deposition date: 2018-09-17, release date: 2019-02-27, Last modification date: 2024-01-24)

• Primary citation: Birgisdottir, A.B.,Mouilleron, S.,Bhujabal, Z.,Wirth, M.,Sjottem, E.,Evjen, G.,Zhang, W.,Lee, R.,O'Reilly, N.,Tooze, S.A.,Lamark, T.,Johansen, T.; Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.; Autophagy, 15:1333-1355, 2019; PubMed: 30767700; DOI: 10.1080/15548627.2019.1581009

Experimental method

X-RAY DIFFRACTION (1.61 Å)