2YDV
| Thermostabilised HUMAN A2a Receptor with NECA bound | 分子名称: | ADENOSINE RECEPTOR A2A, N-ETHYL-5'-CARBOXAMIDO ADENOSINE, octyl 1-thio-beta-D-glucopyranoside | 著者 | Lebon, G, Warne, T, Edwards, P.C, Bennett, K, Langmead, C.J, Leslie, A.G.W, Tate, C.G. | 登録日 | 2011-03-24 | 公開日 | 2011-05-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Agonist-Bound Adenosine A(2A) Receptor Structures Reveal Common Features of Gpcr Activation. Nature, 474, 2011
|
|
2YDO
| Thermostabilised HUMAN A2a Receptor with adenosine bound | 分子名称: | ADENOSINE, ADENOSINE RECEPTOR A2A, octyl 1-thio-beta-D-glucopyranoside | 著者 | Lebon, G, Warne, T, Edwards, P.C, Bennett, K, Langmead, C.J, Leslie, A.G.W, Tate, C.G. | 登録日 | 2011-03-23 | 公開日 | 2011-05-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Agonist-Bound Adenosine A(2A) Receptor Structures Reveal Common Features of Gpcr Activation. Nature, 474, 2011
|
|
4UHR
| Thermostabilised HUMAN A2a Receptor with CGS21680 bound | 分子名称: | 2-[P-(2-CARBOXYETHYL)PHENYLETHYL-AMINO]-5'-N-ETHYLCARBOXAMIDO ADENOSINE, THERMOSTABILISED HUMAN A2A RECEPTOR | 著者 | Lebon, G, Edwards, P.C, Leslie, A.G.W, Tate, C.G. | 登録日 | 2015-03-25 | 公開日 | 2015-04-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular Determinants of Cgs21680 Binding to the Human Adenosine A2A Receptor. Mol.Pharmacol., 87, 2015
|
|
4UG2
| Thermostabilised HUMAN A2a Receptor with CGS21680 bound | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[P-(2-CARBOXYETHYL)PHENYLETHYL-AMINO]-5'-N-ETHYLCARBOXAMIDO ADENOSINE, THERMOSTABILISED HUMAN A2A RECEPTOR | 著者 | Lebon, G, Edwards, P.C, Leslie, A.G.W, Tate, C.G. | 登録日 | 2015-03-21 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular Determinants of Cgs21680 Binding to the Human Adenosine A2A Receptor. Mol.Pharmacol., 87, 2015
|
|
7P2L
| thermostabilised 7TM domain of human mGlu5 receptor bound to photoswitchable ligand alloswitch-1 | 分子名称: | 2-chloranyl-~{N}-[2-methoxy-4-[(~{E})-pyridin-2-yldiazenyl]phenyl]benzamide, Metabotropic glutamate receptor 5,Endolysin,Metabotropic glutamate receptor 5 | 著者 | Huang, C.Y, Vinothkumar, K.R, Lebon, G. | 登録日 | 2021-07-06 | 公開日 | 2021-09-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations. Cell Rep, 36, 2021
|
|
7FD9
| Thermostabilised full length human mGluR5-5M with orthosteric antagonist, LY341495 | 分子名称: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5 | 著者 | Vinothkumar, K.R, Cannone, G, Lebon, G. | 登録日 | 2021-07-16 | 公開日 | 2021-09-08 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations. Cell Rep, 36, 2021
|
|
7FD8
| Thermostabilised full length human mGluR5-5M bound with L-quisqualic acid | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Vinothkumar, K.R, Cannone, G, Lebon, G. | 登録日 | 2021-07-16 | 公開日 | 2021-09-08 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations. Cell Rep, 36, 2021
|
|
7JNI
| Crystal structure of the angiotensin II type 2 receptoror (AT2R) in complex with EMA401 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, HEXANE-1,6-DIOL, ... | 著者 | Cherezov, V, Shaye, H, Han, G.W. | 登録日 | 2020-08-04 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Inhibition of the angiotensin II type 2 receptor AT 2 R is a novel therapeutic strategy for glioblastoma. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
5G53
| Structure of the adenosine A2A receptor bound to an engineered G protein | 分子名称: | ADENOSINE RECEPTOR A2A, ENGINEERED DOMAIN OF HUMAN G ALPHA S LONG ISOFORM, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Carpenter, B, Nehme, R, Warne, T, Leslie, A.G.W, Tate, C.G. | 登録日 | 2016-05-19 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure of the Adenosine A2A Receptor Bound to an Engineered G Protein Nature, 536, 2016
|
|