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1VET
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BU of 1vet by Molmil
Crystal Structure of p14/MP1 at 1.9 A resolution
分子名称: Late endosomal/lysosomal Mp1 interacting protein, Mitogen-activated protein kinase kinase 1 interacting protein 1
著者Kurzbauer, R, Teis, D, Maurer-Stroh, S, Eisenhaber, F, Hekman, M, Bourenkov, G.P, Bartunik, H.D, Huber, L.A, Clausen, T.
登録日2004-04-05
公開日2004-08-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the p14/MP1 scaffolding complex: How a twin couple attaches mitogen- activated protein kinase signaling to late endosomes
Proc.Natl.Acad.Sci.USA, 101, 2004
1VEU
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BU of 1veu by Molmil
Crystal structure of the p14/MP1 complex at 2.15 A resolution
分子名称: Late endosomal/lysosomal Mp1 interacting protein, Mitogen-activated protein kinase kinase 1 interacting protein 1
著者Kurzbauer, R, Teis, D, Maurer-Stroh, S, Eisenhaber, F, Hekman, M, Bourenkov, G.P, Bartunik, H.D, Huber, L.A, Clausen, T.
登録日2004-04-05
公開日2004-08-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the p14/MP1 scaffolding complex: How a twin couple attaches mitogen- activated protein kinase signaling to late endosomes
Proc.Natl.Acad.Sci.USA, 101, 2004
1SOT
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BU of 1sot by Molmil
Crystal Structure of the DegS stress sensor
分子名称: Protease degS
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-15
公開日2004-06-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
1SOZ
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BU of 1soz by Molmil
Crystal Structure of DegS protease in complex with an activating peptide
分子名称: Protease degS, activating peptide
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-16
公開日2004-06-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
2R3U
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BU of 2r3u by Molmil
Crystal structure of the PDZ deletion mutant of DegS
分子名称: Protease degS
著者Clausen, T, Kurzbauer, R.
登録日2007-08-30
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
1VCW
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BU of 1vcw by Molmil
Crystal structure of DegS after backsoaking the activating peptide
分子名称: Protease degS
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-16
公開日2004-06-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.
Cell(Cambridge,Mass.), 117, 2004
4C2D
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BU of 4c2d by Molmil
Crystal structure of the protease CtpB in an active state
分子名称: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
著者Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
登録日2013-08-17
公開日2013-12-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2E
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BU of 4c2e by Molmil
Crystal structure of the protease CtpB(S309A) present in a resting state
分子名称: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB
著者Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
登録日2013-08-17
公開日2013-12-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2C
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BU of 4c2c by Molmil
Crystal structure of the protease CtpB in an active state
分子名称: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
著者Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
登録日2013-08-17
公開日2013-12-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2G
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BU of 4c2g by Molmil
Crystal structure of CtpB(S309A) in complex with a peptide having a Val-Pro-Ala C-terminus
分子名称: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1
著者Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
登録日2013-08-17
公開日2013-12-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2H
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BU of 4c2h by Molmil
Crystal structure of the CtpB(V118Y) mutant
分子名称: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB
著者Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
登録日2013-08-17
公開日2013-12-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
4C2F
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BU of 4c2f by Molmil
Crystal structure of the CtpB R168A mutant present in an active conformation
分子名称: CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2
著者Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T.
登録日2013-08-17
公開日2013-12-04
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
6QDJ
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BU of 6qdj by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ...
著者Meinhart, A, Clausen, T, Arnese, R.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.884 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
5HBN
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BU of 5hbn by Molmil
ClpC N-terminal domain with bound phospho-arginine
分子名称: ACETATE ION, Negative regulator of genetic competence ClpC/MecB, SULFATE ION, ...
著者Suskiewicz, M.J, Clausen, T.
登録日2016-01-01
公開日2016-10-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Arginine phosphorylation marks proteins for degradation by a Clp protease.
Nature, 539, 2016
7BII
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BU of 7bii by Molmil
Crystal structure of Nematocida HUWE1
分子名称: E3 ubiquitin-protein ligase HUWE1
著者Grabarczyk, D.B, Petrova, O.A, Meinhart, A, Kessler, D, Clausen, T.
登録日2021-01-12
公開日2021-07-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.037 Å)
主引用文献HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Nat.Chem.Biol., 17, 2021
6TV6
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BU of 6tv6 by Molmil
Octameric McsB from Bacillus subtilis.
分子名称: MAGNESIUM ION, Protein-arginine kinase
著者Suskiewicz, M.J, Hajdusits, B, Meinhart, A, Clausen, T.
登録日2020-01-09
公開日2021-07-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation.
Elife, 10, 2021
5D4W
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BU of 5d4w by Molmil
Crystal structure of Hsp104
分子名称: ADENOSINE-5'-DIPHOSPHATE, Putative heat shock protein
著者Heuck, A, Schitter-Sollner, S, Clausen, T.
登録日2015-08-09
公開日2016-12-07
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural basis for the disaggregase activity and regulation of Hsp104.
Elife, 5, 2016
2R3Y
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BU of 2r3y by Molmil
Crystal structure of the DegS protease in complex with the YWF activating peptide
分子名称: Protease degS, Synthetic peptide YWF
著者Clausen, T, Hasselblatt, H.
登録日2007-08-30
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
6QDL
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BU of 6qdl by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: UNC-45
著者Meinhart, A, Clausen, T, Hellerschmied, D.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.929 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDM
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BU of 6qdm by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: UNC-45,UNC-45
著者Meinhart, A, Clausen, T, Hellerschmied, D.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDK
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BU of 6qdk by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: UNC-45,UNC-45
著者Meinhart, A, Clausen, T, Hellerschmied, D.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
7AA4
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BU of 7aa4 by Molmil
Structure of ClpC1-NTD bound to a CymA analogue
分子名称: Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue
著者Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T.
登録日2020-09-03
公開日2021-08-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
7ABR
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BU of 7abr by Molmil
Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Negative regulator of genetic competence ClpC/MecB, ...
著者Morreale, F.E, Meinhart, A, Haselbach, D, Clausen, T.
登録日2020-09-08
公開日2021-10-06
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
8ATX
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BU of 8atx by Molmil
Cryo-EM structure of human BIRC6 - no substrate
分子名称: Baculoviral IAP repeat-containing protein 6, ZINC ION
著者Ehrmann, J.F, Grabarczyk, D.B, Clausen, T.
登録日2022-08-24
公開日2023-02-15
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science, 379, 2023
8AUW
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BU of 8auw by Molmil
Cryo-EM structure of human BIRC6 in complex with SMAC.
分子名称: Baculoviral IAP repeat-containing protein 6, Diablo IAP-binding mitochondrial protein, ZINC ION
著者Ehrmann, J.F, Grabarczyk, D.B, Clausen, T.
登録日2022-08-25
公開日2023-02-15
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science, 379, 2023

 

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