7SQ1
 
 | | BG505.MD39TS Env trimer in complex with Fab from antibody C05 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C05 Fab Light chain, ... | | 著者 | Moore, A, Du, J, Xu, Z, Walker, S, Kulp, D.W, Pallesen, J. | | 登録日 | 2021-11-04 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.
Nat Commun, 13, 2022
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2KZ2
 | | Calmodulin, C-terminal domain, F92E mutant | | 分子名称: | CALCIUM ION, Calmodulin | | 著者 | Korendovych, I, Kulp, D, Wu, Y, Cheng, H, Roder, H, DeGrado, W. | | 登録日 | 2010-06-10 | | 公開日 | 2011-04-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design of a switchable eliminase.
Proc.Natl.Acad.Sci.USA, 108, 2011
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5T3S
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6NFC
 | | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP42 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP42 fragment antigen binding heavy chain, ... | | 著者 | Ozorowski, G, Torres, J.L, Ward, A.B. | | 登録日 | 2018-12-19 | | 公開日 | 2019-11-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | | 主引用文献 | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
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6D2P
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6DFH
 | | BG505 MD64 N332-GT2 SOSIP trimer in complex with germline-reverted BG18 fragment antigen binding | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | 著者 | Ozorowski, G, Steichen, J.M, Schief, W.R, Ward, A.B. | | 登録日 | 2018-05-14 | | 公開日 | 2019-11-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
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6NF5
 | | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP1 fragment antigen binding heavy chain, ... | | 著者 | Ozorowski, G, Torres, J.L, Steichen, J.M, Schief, W.R, Ward, A.B. | | 登録日 | 2018-12-18 | | 公開日 | 2019-11-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
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6DFG
 | | BG505 MD39 SOSIP trimer in complex with mature BG18 fragment antigen binding | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | 著者 | Ozorowski, G, Steichen, J.M, Schief, W.R, Ward, A.B. | | 登録日 | 2018-05-14 | | 公開日 | 2019-11-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.42 Å) | | 主引用文献 | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
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6OC7
 | | HMP42 Fab in complex with Protein G | | 分子名称: | Heavy chain of HMP42 Fab, Immunoglobulin G-binding protein G, Light chain for HMP42 Fab | | 著者 | Bernard, S.M, Wilson, I.A. | | 登録日 | 2019-03-22 | | 公開日 | 2020-02-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.296 Å) | | 主引用文献 | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
Science, 366, 2019
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8U08
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8U03
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8TZN
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8TZW
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8V2E
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5IF0
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5IDL
 | | Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT8 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT8 | | 著者 | Julien, J.P, Ereno-Orbea, J, Jardine, J.G, Schief, W.R, Wilson, I.A. | | 登録日 | 2016-02-24 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
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5IES
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5IFA
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7RA7
 | | Crystal structure of rabbit anti-HIV Fab 11A | | 分子名称: | 11A Fab heavy chain, 11A Fab light chain, PENTAETHYLENE GLYCOL, ... | | 著者 | Oyen, D, Wilson, I.A. | | 登録日 | 2021-06-30 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions
To Be Published
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8SX3
 | | 10E8-GT10.2 immunogen in complex with human Fab 10E8 and mouse Fab W6-10 | | 分子名称: | 10E8 Fab heavy chain, 10E8 light chain, 10E8-GT10.2 immunogen, ... | | 著者 | Huang, J, Ozorowski, G, Ward, A.B. | | 登録日 | 2023-05-19 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
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8D8R
 | | SARS-CoV-2 Spike RBD in complex with DMAb 2196 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2196 heavy chain, 2196 light chain, ... | | 著者 | Du, J, Cui, J, Pallesen, J. | | 登録日 | 2022-06-08 | | 公開日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Nat Commun, 13, 2022
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8D8Q
 | | SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2130 heavy chain, 2130 light chain, ... | | 著者 | Du, J, Cui, J, Pallesen, J. | | 登録日 | 2022-06-08 | | 公開日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Nat Commun, 13, 2022
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