3MDD
 
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3MDE
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2CW6
 | | Crystal Structure of Human HMG-CoA Lyase: Insights into Catalysis and the Molecular Basis for Hydroxymethylglutaric Aciduria | | 分子名称: | 3-HYDROXYPENTANEDIOIC ACID, Hydroxymethylglutaryl-CoA lyase, mitochondrial, ... | | 著者 | Fu, Z, Runquist, J.A, Hunt, J.F, Miziorko, H.M, Kim, J.-J.P. | | 登録日 | 2005-06-17 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of human 3-hydroxy-3-methylglutaryl-CoA Lyase: insights into catalysis and the molecular basis for hydroxymethylglutaric aciduria
J.Biol.Chem., 281, 2006
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1Q25
 | | Crystal structure of N-terminal 3 domains of CI-MPR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Olson, L.J, Dahms, N.M, Kim, J.-J.P. | | 登録日 | 2003-07-23 | | 公開日 | 2004-06-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of uPAR, plasminogen, and sugar-binding sites of the 300 kDa mannose 6-phosphate receptor
Embo J., 23, 2004
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1SZ0
 | | N-terminal 3 domains of CI-MPR bound to mannose 6-phosphate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Olson, L.J, Dahms, N.M, Kim, J.-J.P. | | 登録日 | 2004-04-01 | | 公開日 | 2004-06-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The N-terminal carbohydrate recognition site of the cation-independent mannose 6-phosphate receptor
J.Biol.Chem., 279, 2004
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1SYO
 | | N-terminal 3 domains of CI-MPR bound to mannose 6-phosphate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-alpha-D-mannopyranose, GLYCEROL, ... | | 著者 | Olson, L.J, Dahms, N.M, Kim, J.-J.P. | | 登録日 | 2004-04-01 | | 公開日 | 2004-06-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The N-terminal carbohydrate recognition site of the cation-independent mannose 6-phosphate receptor
J.Biol.Chem., 279, 2004
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2G7N
 | | Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to small Molecule Inhibitors | | 分子名称: | Botulinum neurotoxin type A, SILVER ION, ZINC ION | | 著者 | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | | 登録日 | 2006-02-28 | | 公開日 | 2007-03-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the Light Chain of Botulinum Neurotoxin Serotype A bound to Small Molecule Inhibitors
To be Published
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2IQ6
 | | Crystal Structure of the Aminopeptidase from Vibrio proteolyticus in Complexation with Leucyl-leucyl-leucine. | | 分子名称: | Bacterial leucyl aminopeptidase, Peptide, (Leucyl-leucyl-leucine), ... | | 著者 | Kumar, A, Narayanan, B, Kim, J.-J.P, Bennett, B. | | 登録日 | 2006-10-13 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Experimental evidence for a metallohydrolase mechanism in which the nucleophile is not delivered by a metal ion: EPR spectrokinetic and structural studies of aminopeptidase from Vibrio proteolyticus
Biochem.J., 403, 2007
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3N7K
 | | Crystal structure of botulinum neurotoxin serotype C1 binding domain | | 分子名称: | Botulinum neurotoxin type C1 | | 著者 | Fu, Z, Kroken, A, Karalewitz, A, Baldwin, M.R, Barbieri, J.T, Kim, J.-J.P. | | 登録日 | 2010-05-27 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .
Biochemistry, 49, 2010
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3N7J
 | | Crystal structure of botulinum neurotoxin serotype D binding domain | | 分子名称: | Botulinum neurotoxin type D | | 著者 | Fu, Z, Baldwin, M.R, Karalewitz, A, Kroken, A, Barbieri, J.T, Kim, J.-J.P. | | 登録日 | 2010-05-27 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .
Biochemistry, 49, 2010
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3N7L
 | | Crystal structure of botulinum neurotoxin serotype D/C VPI 5993 binding domain | | 分子名称: | GLYCEROL, Neurotoxin, SULFATE ION | | 著者 | Fu, Z, Karalewitz, A, Kroken, A, Baldwin, M.R, Barbieri, J.T, Kim, J.-J.P. | | 登録日 | 2010-05-27 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .
Biochemistry, 49, 2010
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1KEO
 | | TWISTS AND TURNS OF THE CD-MPR: LIGAND-BOUND VERSUS LIGAND-FREE RECEPTOR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, cation-dependent mannose-6-phosphate receptor | | 著者 | Olson, L.J, Zhang, J, Dahms, N.M, Kim, J.J. | | 登録日 | 2001-11-16 | | 公開日 | 2002-01-23 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor
J.Biol.Chem., 277, 2002
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6P8I
 | | N-terminal 5 domains of IGFIIR | | 分子名称: | Cation-independent mannose-6-phosphate receptor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Olson, L.J, Dahms, N.M, Kim, J.-J.P. | | 登録日 | 2019-06-07 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor.
Commun Biol, 3, 2020
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4XQM
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4FVV
 | | Crystal structure of HCR/D-Sa-GBL1/C | | 分子名称: | GLYCEROL, N-acetyl-alpha-neuraminic acid, Neurotoxin, ... | | 著者 | Fu, Z, Karalewitz, A, Baldwin, M.R, Kim, J.-J.P, Barbieri, J.T. | | 登録日 | 2012-06-29 | | 公開日 | 2012-10-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.
J.Biol.Chem., 287, 2012
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6V02
 | | N-terminal 5 domains of CI-MPR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cation-independent mannose-6-phosphate receptor | | 著者 | Olson, L.J, Dahms, N.M, Kim, J.-J.P. | | 登録日 | 2019-11-18 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Allosteric regulation of lysosomal enzyme recognition by the cation-independent mannose 6-phosphate receptor.
Commun Biol, 3, 2020
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1JQI
 | | Crystal Structure of Rat Short Chain Acyl-CoA Dehydrogenase Complexed With Acetoacetyl-CoA | | 分子名称: | ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, short chain acyl-CoA dehydrogenase | | 著者 | Battaile, K.P, Molin-Case, J, Paschke, R, Wang, M, Bennett, D, Vockley, J, Kim, J.-J.P. | | 登録日 | 2001-08-07 | | 公開日 | 2002-02-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure of rat short chain acyl-CoA dehydrogenase complexed with acetoacetyl-CoA: comparison with other acyl-CoA dehydrogenases.
J.Biol.Chem., 277, 2002
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4IQP
 | | Crystal Structure of HCRA-W1266A | | 分子名称: | Botulinum neurotoxin type A, GLYCEROL | | 著者 | Fu, Z, Kroken, A.R, Barbieri, J.T, Kim, J.-J.P. | | 登録日 | 2013-01-12 | | 公開日 | 2013-05-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Enhancing the Protective Immune Response against Botulism.
Infect.Immun., 81, 2013
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3CY4
 | | Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 7.4 | | 分子名称: | Cation-dependent mannose-6-phosphate receptor, GLYCEROL, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Olson, L.J, Hindsgaul, O, Dahms, N.M, Kim, J.-J.P. | | 登録日 | 2008-04-25 | | 公開日 | 2008-05-13 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.
J.Biol.Chem., 283, 2008
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3D4J
 | | Crystal structure of Human mevalonate diphosphate decarboxylase | | 分子名称: | Diphosphomevalonate decarboxylase, SULFATE ION | | 著者 | Voynova, N.E, Fu, Z, Battaile, K, Herdendorf, T.J, Kim, J.-J.P, Miziorko, H.M. | | 登録日 | 2008-05-14 | | 公開日 | 2008-12-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure.
Arch.Biochem.Biophys., 480, 2008
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2RL9
 | | Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 6.5 bound to trimannoside | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, Cation-dependent mannose-6-phosphate receptor, ... | | 著者 | Olson, L.J, Hindsgaul, O, Dahms, N.M, Kim, J.-J.P. | | 登録日 | 2007-10-18 | | 公開日 | 2008-02-12 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into the mechanism of pH-dependent ligand binding and release by the cation-dependent mannose 6-phosphate receptor.
J.Biol.Chem., 283, 2008
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2RL7
 | | Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 4.8 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CACODYLATE ION, ... | | 著者 | Olson, L.J, Hindsgaul, O, Kim, J.-J.P, Dahms, N.M. | | 登録日 | 2007-10-18 | | 公開日 | 2008-02-12 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.
J.Biol.Chem., 283, 2008
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2RL8
 | | Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 6.5 bound to M6P | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-beta-D-mannopyranose, Cation-dependent mannose-6-phosphate receptor, ... | | 著者 | Olson, L.J, Hindsgaul, O, Kim, J.-J.P, Dahms, N.M. | | 登録日 | 2007-10-18 | | 公開日 | 2008-02-12 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.
J.Biol.Chem., 283, 2008
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2RLB
 | | Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 6.5 bound to M6P in absence of Mn | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-beta-D-mannopyranose, Cation-dependent mannose-6-phosphate receptor | | 著者 | Olson, L.J, Hindsgaul, O, Dahms, N.M, Kim, J.-J.P. | | 登録日 | 2007-10-18 | | 公開日 | 2008-02-12 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.
J.Biol.Chem., 283, 2008
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3MP3
 | | Crystal Structure of Human Lyase in complex with inhibitor HG-CoA | | 分子名称: | (3R,5S,9R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8-dimethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide, 3-HYDROXYPENTANEDIOIC ACID, Hydroxymethylglutaryl-CoA lyase, ... | | 著者 | Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P. | | 登録日 | 2010-04-24 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
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