Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 7.4

Replaces:  2RL6

Summary for 3CY4

Related2RL7 2RL8 2RL9 2RLB
DescriptorCation-dependent mannose-6-phosphate receptor, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ... (5 entities in total)
Functional Keywordsp-type lectin, receptor, mannose 6-phosphate, lectin, glycoprotein, lysosome, membrane, transmembrane, transport, protein transport, sugar binding protein
Biological sourceBos taurus (cattle)
Cellular locationLysosome membrane ; Single-pass type I membrane protein  P11456
Total number of polymer chains2
Total molecular weight36945.02
Olson, L.J.,Hindsgaul, O.,Dahms, N.M.,Kim, J.-J.P. (deposition date: 2008-04-25, release date: 2008-05-13, Last modification date: 2017-10-25)
Primary citation
Olson, L.J.,Hindsgaul, O.,Dahms, N.M.,Kim, J.J.
Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor.
J.Biol.Chem., 283:10124-10134, 2008
PubMed: 18272523 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M708994200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.246701.5%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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