2RLB
Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 6.5 bound to M6P in absence of Mn
Summary for 2RLB
Entry DOI | 10.2210/pdb2rlb/pdb |
Related | 2RL6 2RL7 2RL8 2RL9 |
Descriptor | Cation-dependent mannose-6-phosphate receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-beta-D-mannopyranose, ... (4 entities in total) |
Functional Keywords | p-type lectin, receptor, mannose 6-phosphate, lectin, glycoprotein, lysosome, membrane, transmembrane, transport, protein transport, sugar binding protein |
Biological source | Bos taurus (cattle) |
Cellular location | Lysosome membrane ; Single-pass type I membrane protein : P11456 |
Total number of polymer chains | 2 |
Total formula weight | 35849.85 |
Authors | Olson, L.J.,Hindsgaul, O.,Dahms, N.M.,Kim, J.-J.P. (deposition date: 2007-10-18, release date: 2008-02-12, Last modification date: 2021-10-20) |
Primary citation | Olson, L.J.,Hindsgaul, O.,Dahms, N.M.,Kim, J.J. Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor. J.Biol.Chem., 283:10124-10134, 2008 Cited by PubMed: 18272523DOI: 10.1074/jbc.M708994200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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