2RLB

Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 6.5 bound to M6P in absence of Mn

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Cation-dependent mannose-6-phosphate receptor	polymer	154	17443.6	2	UniProt (P11456) Pfam (PF02157) In PDB	Bos taurus (cattle)	CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46
2	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
3	A, B	6-O-phosphono-beta-D-mannopyranose	non-polymer		260.1	2	Chemie (M6D)
4		water	water		18.0	286	Chemie (HOH)

Sequence modifications

A, B: 1 - 154 (UniProt: P11456)

PDB	External Database	Details
Gln 31	Asn 59	engineered mutation
Gln 57	Asn 85	engineered mutation
Gln 68	Asn 96	engineered mutation
Gln 87	Asn 115	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34887.2
Non-Polymers*	Number of molecules	4
	Total formula weight	962.7
All*	Total formula weight	35849.8

*Water molecules are not included.