6U5L
| Structure of human ULK4 in complex with an inhibitor | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, N~2~-(1H-benzimidazol-6-yl)-N~4~-(5-cyclobutyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine, ... | 著者 | Khamrui, S, Lazarus, M.B. | 登録日 | 2019-08-28 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | High-Resolution Structure and Inhibition of the Schizophrenia-Linked Pseudokinase ULK4. J.Am.Chem.Soc., 142, 2020
|
|
4GGN
| Malaria invasion machinery protein complex | 分子名称: | Myosin A tail domain interacting protein MTIP, Myosin-A | 著者 | Khamrui, S, Turley, S, Bergman, L.W, Hol, W.G.J. | 登録日 | 2012-08-06 | 公開日 | 2013-07-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody. Mol.Biochem.Parasitol., 190, 2013
|
|
4GFT
| Malaria invasion machinery protein-Nanobody complex | 分子名称: | 1,2-ETHANEDIOL, Myosin A tail domain interacting protein, Nanobody | 著者 | Khamrui, S, Turley, S, Pardon, E, Steyaert, J, Verlinde, C, Fan, E, Bergman, L.W, Hol, W.G.J. | 登録日 | 2012-08-03 | 公開日 | 2013-07-03 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody. Mol.Biochem.Parasitol., 190, 2013
|
|
1XG6
| |
3I2X
| Crystal structure of a chimeric trypsin inhibitor having reactive site loop of ETI on the scaffold of WCI | 分子名称: | Chymotrypsin inhibitor 3 | 著者 | Sen, U, Khamrui, S, Dasgupta, J, Dattagupta, J.K, Majumder, S. | 登録日 | 2009-06-30 | 公開日 | 2010-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Identification of a novel set of scaffolding residues that are instrumental for the inhibitory property of Kunitz (STI) inhibitors. Protein Sci., 19, 2010
|
|
3I29
| Crystal structure of a binary complex between an mutant trypsin inhibitor with bovine trypsin | 分子名称: | CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3 | 著者 | Khamrui, S, Majumder, S, Dasgupta, J, Dattagupta, J.K, Sen, U. | 登録日 | 2009-06-29 | 公開日 | 2010-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors Biochim.Biophys.Acta, 1824, 2012
|
|
3I2A
| |
2QYI
| Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin | 分子名称: | CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3, ... | 著者 | Khamrui, S, Dasgupta, J, Dattagupta, J.K, Sen, U. | 登録日 | 2007-08-15 | 公開日 | 2008-08-19 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of a binary complex between an engineered trypsin inhibitor and Bovine trypsin To be Published
|
|
6U3J
| |
8E8U
| Structure of the LOR domain of human AASS | 分子名称: | Alpha-aminoadipic semialdehyde synthase, mitochondrial, MAGNESIUM ION | 著者 | Khamrui, S, Lazarus, M.B. | 登録日 | 2022-08-25 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1. Open Biology, 12, 2022
|
|
8E8V
| |
8E8T
| Structure of the short LOR domain of human AASS | 分子名称: | Alpha-aminoadipic semialdehyde synthase, mitochondrial | 著者 | Khamrui, S, Lazarus, M.B. | 登録日 | 2022-08-25 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1. Open Biology, 12, 2022
|
|
6UWY
| DYRK1A bound to a harmine derivative | 分子名称: | 4-(7-methoxy-1-methyl-9H-beta-carbolin-9-yl)butanamide, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, TETRAETHYLENE GLYCOL | 著者 | Khamrui, S, Lazarus, M.B. | 登録日 | 2019-11-05 | 公開日 | 2020-02-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Synthesis and Biological Validation of a Harmine-Based, Central Nervous System (CNS)-Avoidant, Selective, Human beta-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor. J.Med.Chem., 63, 2020
|
|
2BEB
| X-ray structure of Asn to Thr mutant of Winged Bean Chymotrypsin inhibitor | 分子名称: | Chymotrypsin inhibitor 3 | 著者 | Dattagupta, J.K, Sen, U, Dasgupta, J, Khamrui, S. | 登録日 | 2005-10-24 | 公開日 | 2006-06-13 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Spacer Asn Determines the Fate of Kunitz (STI) Inhibitors, as Revealed by Structural and Biochemical Studies on WCI Mutants. Biochemistry, 45, 2006
|
|
2BEA
| Crystal structure of Asn14 to Gly mutant of WCI | 分子名称: | Chymotrypsin inhibitor 3 | 著者 | Dattagupta, J.K, Sen, U, Dasgupta, J, Khamrui, S. | 登録日 | 2005-10-24 | 公開日 | 2006-06-13 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Spacer Asn Determines the Fate of Kunitz (STI) Inhibitors, as Revealed by Structural and Biochemical Studies on WCI Mutants. Biochemistry, 45, 2006
|
|
2ET2
| Crystal structure of an Asn to Ala mutant of Winged Bean Chymotrypsin Inhibitor protein | 分子名称: | Chymotrypsin inhibitor 3, NICKEL (II) ION, SULFATE ION | 著者 | Dattagupta, J.K, Sen, U, Dasgupta, J, Khamrui, S. | 登録日 | 2005-10-27 | 公開日 | 2006-06-13 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Spacer Asn Determines the Fate of Kunitz (STI) Inhibitors, as Revealed by Structural and Biochemical Studies on WCI Mutants. Biochemistry, 45, 2006
|
|
2ESU
| Crystal structure of Asn to Gln mutant of Winged Bean Chymotrypsin Inhibitor protein | 分子名称: | Chymotrypsin inhibitor 3, NICKEL (II) ION, SULFATE ION | 著者 | Dattagupta, J.K, Sen, U, Dasgupta, J, Khamrui, S. | 登録日 | 2005-10-27 | 公開日 | 2006-06-13 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Spacer Asn Determines the Fate of Kunitz (STI) Inhibitors, as Revealed by Structural and Biochemical Studies on WCI Mutants. Biochemistry, 45, 2006
|
|
3QYD
| Crystal structure of a recombinant chimeric trypsin inhibitor | 分子名称: | Chymotrypsin inhibitor 3 | 著者 | Sen, U, Majumder, S, Khamrui, S, Dasgupta, J. | 登録日 | 2011-03-03 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors Biochim.Biophys.Acta, 1824, 2012
|
|
3RX6
| Crystal structure of Polarity Suppression protein from Enterobacteria phage P4 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IODIDE ION, MERCURY (II) ION, ... | 著者 | Banerjee, R, Nath, S, Khamrui, S, Sen, R, Sen, U. | 登録日 | 2011-05-10 | 公開日 | 2012-07-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.039 Å) | 主引用文献 | The first structure of polarity suppression protein, Psu from enterobacteria phage P4, reveals a novel fold and a knotted dimer J.Biol.Chem., 287, 2012
|
|
3VEQ
| A binary complex betwwen bovine pancreatic trypsin and a engineered mutant trypsin inhibitor | 分子名称: | CALCIUM ION, Cationic trypsin, Chymotrypsin inhibitor 3 | 著者 | Sen, U, Majumder, S, Khamrui, S, Dasgupta, J. | 登録日 | 2012-01-09 | 公開日 | 2012-10-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Role of remote scaffolding residues in the inhibitory loop pre-organization, flexibility, rigidification and enzyme inhibition of serine protease inhibitors Biochim.Biophys.Acta, 1824, 2012
|
|
4TLP
| Crystal structure of a alanine91 mutant of WCI | 分子名称: | Chymotrypsin inhibitor 3 | 著者 | Sen, U, Majumder, S. | 登録日 | 2014-05-30 | 公開日 | 2014-07-02 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A conserved tryptophan (W91) at the barrel-lid junction modulates the packing and stability of Kunitz (STI) family of inhibitors. Biochim.Biophys.Acta, 1854, 2015
|
|
4LX8
| |
4JP1
| |
4H60
| |
3TO5
| |