Crystal structure of a alanine91 mutant of WCI

Summary for 4TLP

DescriptorChymotrypsin inhibitor 3 (2 entities in total)
Functional Keywordshydrolase, inhibitor, chymotrypsin inhibitor, tryptophan
Biological sourcePsophocarpus tetragonolobus (Winged bean)
Total number of polymer chains1
Total molecular weight19340.97
Sen, U.,Majumder, S. (deposition date: 2014-05-30, release date: 2014-07-02, Last modification date: 2019-02-13)
Primary citation
Majumder, S.,Khamrui, S.,Banerjee, R.,Bhowmik, P.,Sen, U.
A conserved tryptophan (W91) at the barrel-lid junction modulates the packing and stability of Kunitz (STI) family of inhibitors.
Biochim.Biophys.Acta, 1854:55-64, 2015
PubMed: 25448016 (PDB entries with the same primary citation)
DOI: 10.1016/j.bbapap.2014.10.021
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2072 1.2% 5.3% 4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-08-12