8E8T
Structure of the short LOR domain of human AASS
Summary for 8E8T
| Entry DOI | 10.2210/pdb8e8t/pdb |
| Descriptor | Alpha-aminoadipic semialdehyde synthase, mitochondrial (2 entities in total) |
| Functional Keywords | lysine metabolism, ketoglutarate, mitochondrial, reductase, oxidoreductase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 96694.27 |
| Authors | Khamrui, S.,Lazarus, M.B. (deposition date: 2022-08-25, release date: 2022-10-05, Last modification date: 2023-10-18) |
| Primary citation | Leandro, J.,Khamrui, S.,Suebsuwong, C.,Chen, P.J.,Secor, C.,Dodatko, T.,Yu, C.,Sanchez, R.,DeVita, R.J.,Houten, S.M.,Lazarus, M.B. Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1. Open Biology, 12:220179-220179, 2022 Cited by PubMed: 36128717DOI: 10.1098/rsob.220179 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.18 Å) |
Structure validation
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